Senior Agentic Systems Engineer

Job Description Senior Agentic Systems Engineer Natera San Carlos, CA On-site, Remote $124,800—$156,000 USD Annual Position Summary Join Natera's Therapeutics & Innovations group as a Senior Agentic Systems Engineer to build Artificial Intelligence (AI) orchestration platforms. You will design, scale, and deploy generative AI (GenAI) and Large Language Model (LLM) agentic systems that leverage our multimodal data to advance therapeutic development. As the platform matures, you will own cross-product agent integration and the development of new specialist tools. Primary Responsibilities Architect, implement, and maintain AI agent orchestration platforms, spanning multi-agent delegation, session management, and streaming interfaces. Design and build Model Context Protocol (MCP) servers that expose domain-specific capabilities as composable tools. Implement rigorous security and isolation boundaries, including sandboxed code execution, scoped permissions, Human-in-the-Loop (HITL) workflows, and tenant-aware data access. Deploy and operate containerized services on AWS using Terraform, optimizing for cost, reliability, and observability based on data. Partner directly with ML engineers, data engineers, and product teams to integrate specialist agents without needing translation layers. Own and advance technical solutions from concept to deployment, pressure-testing assumptions and closing gaps without waiting for a finished playbook. Use data to root-cause and resolve complex issues across agent orchestration, infrastructure, and LLM providers in a distributed environment. Write precise, tested Python code, treating quality and reliability as foundational standards rather than an afterthought. Qualifications BS/MS in Computer Science or a related field. 5+ years of production software engineering experience, with a significant focus on backend systems, platform engineering, or infrastructure. Knowledge, Skills, And Abilities Python: Advanced proficiency in writing maintainable, production-quality code. AI Systems: Direct experience building AI agentic systems in production (tool calling, multi-agent orchestration, autonomous task execution). GenAI Ecosystem: Deep familiarity with LLMs, orchestration frameworks, MCP, memory strategies, and execution sandboxing. Cloud & Infrastructure: Hands-on experience with AWS, containerized services, and Infrastructure as Code (Terraform). Security: Clear understanding of security and isolation in environments where AI agents execute code or access sensitive data. Communication: Ability to articulate technical tradeoffs clearly to cross-functional stakeholders. Strategic Mindset: Operate with a 'build vs. buy' mindset to scale capabilities rapidly. Industry Background: Background in biotech, healthcare, or regulated multi-tenant data environments is preferred. Benefits Comprehensive medical, dental, vision, life, and disability plans. Free testing and fertility care benefits for employees and immediate families. Pregnancy and baby bonding leave. 401k benefits and commuter benefits. Generous employee referral program. #J-18808-Ljbffr ChatGPT Jobs