Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Product Engineer

$180k - $285k

HorizonAI Talent

AI Product Engineer - Series B Healthcare AI (SoMa, San Francisco)

San Francisco (SoMa) · 4 days onsite · $180K–$285K base + competitive equity · Visa sponsorship considered (H-1B transfers, TN, OPT) · Relocation support available · 2–4 hires

The short version

I'm running an exclusive search for a Series B healthcare AI company in San Francisco. Series B just closed with two of the best-known Sand Hill Road names on the round - general partners themselves, not associates. Revenue went from $200K to $10M last year . Product is live inside two of the highest-bar academic medical centres in the US. Named World's Most Innovative in 2026 and Best in AI Implementation in 2025.

They are 24 people, 7 in engineering, deliberately keeping the team small. The seat is an AI Product Engineer working directly with the VP of Engineering on the platform that lets health systems build, share and deploy AI agents for clinical and operational work.

Around fifty patients so far have had treatment they otherwise wouldn't - and the reason each time is a workflow one of these engineers shipped. That's the tone of the work.

What they're building

A platform for health systems to build, share and deploy AI agents across clinical and operational tasks. The mental model is the three-step loop that runs most clinical work: pull the knowledge, reason over it, take the action. Same product shape as the agent platforms hitting sales and support right now, in a much harder industry - the users aren't developers, the stakes are life-ending and the buyers are among the most conservative in the world.

They bet early on agentic capability. That means every frontier-model release makes the product materially better out of the box and the engineering team gets to focus on the layer above - orchestration, evals, primitives, the last-mile UI a clinician actually clicks.

What you'd actually do
  • Own product features end-to-end - ideation, design, build, ship, deploy. There are no PMs.
  • Build and scale agentic workflows and agent primitives for reliable long-running clinical reasoning.
  • Roughly 65% backend, 35% frontend on the first hire. Python for backend, React/TypeScript for frontend. Rust and Kubernetes are learnable on the job - don't rule yourself out on those.
  • Split your time roughly half on code and half on planning, reviewing, and thinking about user impact and architecture.
  • Interface directly with clinicians, end-users and customer call recordings. You are the one hearing the pain and shipping against it.
  • Contribute ~60–70% on top of existing infrastructure, ~30–40% net-new.

The team is flat, async and product-driven. No standups. No PMs. Everyone reports to the VP of Engineering. If you like sprints, tickets and layered management, this is not for you!

Who they're looking for

2-8 years of full-time software engineering - sweet spot 4-6. The seat is squarely IC-builder; engineers who've moved into management or want to, this isn't the one.

CS degree is stated. Strong Python for backend is non-negotiable. React/TypeScript on the frontend. Familiarity with Rust, Kubernetes, Helm and AWS is welcome but the team have said clearly these are learnable on the job.

The load-bearing gate (and the one worth being honest with yourself about) is what the HM calls "one clear peak." At least one of the following on your CV:

  • Strong CS degree (think top-10-adjacent - Stanford/MIT/Berkeley/CMU tier, but the team has interviewed strong Berkeley and UCLA profiles, so read this as "top-tier practical bar" rather than a strict ranking).
  • Fast promotion at a recognisable engineering-culture company.
  • Founding engineer at a VC-backed startup during a real growth phase.
  • Standout team at a hard-to-enter organisation (Stripe/Palantir/Scale/Databricks/Anthropic-tier).

Zero peaks is an auto-reject. One clear peak is the floor. Two is comfortable.

Beyond the peak gate, what actually clears interviews:

  • Real end-to-end product feature ownership without a PM holding the pen.
  • Genuine production experience with agentic workflows or LLM-based systems - shipped, not "familiar with."
  • Product thinking. Because there are no PMs, the interview loop specifically tests whether you can reason about end-user impact, not just implementation.
  • High ownership. The team will not chase you.
  • Bonus, not required: healthcare or healthtech background.
What "great" looks like (in the HM's own vocabulary)

There's a distinction worth knowing up front, because it's the lever on the pay band:

  • Solid - clears the peak gate, executes independently, owns a vertical, learns the domain on the job. Lands mid-band.
  • Great - multiple peaks on the CV (top school + name-brand company + founding shape at a fast-growth startup), directly relevant agentic/production AI experience, product intuition already there. This is the profile that unlocks the top of the band and full flexibility on relocation.

The ideal-profile calibration the HM shared makes this concrete. The top of the list is a top-10 CS graduate who ran forward-deployed at a name-brand data-platform company and then went early at a healthtech scale-up. The would-interview cutoff sits at "school not top-10 but founding AI engineer at a real Series B" - one strong marker, clean shape.

What won't work

Straight from the client, so you don't waste your time or theirs:

  • Zero peaks on the CV - no strong school, no name-brand company, no founding-shape at a growth startup, no standout-team at a hard-to-enter org. This is the wall.
  • Legacy enterprise or IT-services backgrounds - Oracle, SAP, IBM, Infosys, Wipro, Cognizant, Accenture, Capgemini-shape. Multiple candidates from these backgrounds have struggled in the interview loop and the HM has told me directly it's a heuristic reject.
  • Long careers in Java-on-Spring, big teams, long planning cycles. This environment burns that shape and they know it.
  • Serial job-hopping - multiple founding roles under one year each without a real story is a stated trait-to-avoid.
  • Frontend-primary CVs. Role is 65% backend, so a UI-only career is a fit-shape reject even if the peak is there.
  • Senior engineers who've moved into management and want to stay there. The seat is IC.
  • Currently on your final H-1B lottery attempt with no overseas fallback. Small US-only team, nowhere to move you to if the lottery doesn't come through.
The details
  • Location. San Francisco, SoMa. 4 days a week onsite. Relocation support is genuinely on the table for the right candidate.
  • Comp. $180K–$285K base plus competitive equity. Strong Series B numbers, not frontier-lab numbers.
  • Visa. Open to new H-1B, H-1B transfers, TN, OPT. Preference caveat above on final-lottery-attempt profiles.
  • Team. 24 people total, 7 in engineering. Flat, async, no standups, no PMs. Reports into the VP of Engineering.
  • Timeline. First hire in 3-4 weeks. Subsequent hires roughly monthly.
Why this one is genuinely worth a conversation
  • The investors and the traction are real. $200K to $10M in a year, live inside two of the highest-bar academic medical centres in the country, Series B closed with GPs personally on the round. Different pressure profile from most Series Bs - they're not raising in a hurry.
  • The engineering shape is the actual selling point. Flat 7-person team, no PMs, no standups, everyone owns product end-to-end. If you've been the engineer quietly holding the product together without the org chart to match, this is a seat where that's the job description, not the workaround.
  • The AI work is the product. Agent primitives, orchestration, evals on live clinical workflows - not a bolt-on. Every frontier-model release makes the product better; the team gets to focus on the layer above.
  • Foundational hire. Going from 7 to 9–11 engineers over the next six months, then holding lean for a long time. The patterns and tooling you set will be what everyone builds on afterwards.
  • The domain is unglamorous and important. Fifty patients so far have had treatment they otherwise wouldn't have. That number will grow and the reason each time will be a workflow an engineer on this team shipped.

Thanks,

#J-18808-Ljbffr
Vacancy posted 22 hours ago
Similar jobs that could be interesting for youBased on the Product Engineer in San Francisco, CA vacancy
  • $107.4k - $155.7k

     ...technologies that redefine how the world works, creates, and collaborates. We’re assembling a diverse, world-class team—engineers, designers, researchers, and product minds—focused on creating an intelligent ecosystem across HP’s portfolio. Together, we’re developing intuitive,... 
    Suggested
    Full time
    Temporary work
    Internship
    Local area
    Flexible hours

    HP

    San Francisco, CA
    2 days ago
  •  ...exclusive features. Direct message the job poster from Novel Technology Services Our client is looking for theirfirst dedicated product engineer. They are an AI driven startup to produce the data and evals necessary for comprehensively automating work enabling agents to... 
    Suggested
    Full time
    Remote work

    Novel Technology Services

    San Francisco, CA
    4 days ago
  •  ...the hard out of hardware, by developing the first AI Hardware Engineer. Our goal is to democratize the ability to create bleeding edge...  ...electronics together in the browser. As a Senior Product Engineer, Front, you will focus on the web application experience... 
    Suggested
    Internship
    Work at office
    Relocation
    Shift work

    Flux Enterprise

    San Francisco, CA
    4 days ago
  • $200k - $275k

     ...- $275,000.00/yr Direct message the job poster from Confero Hiring Staff/Principal Software and Security Engineers for IAM, AppSec and AI Security vendors Product Engineer | AI Agents for Enterprise Compliance | $280K DOE + Equity | Palo Alto Confero is partnered with... 
    Suggested
    Full time

    Confero Inc

    San Francisco, CA
    4 days ago
  • $150k - $250k

     ...Artie Artie is a real-time streaming platform that moves production data across systems in real time, with zero maintenance. We make...  ...-volume data replication simple, reliable, and scalable for engineering teams. Artie is a real-time streaming platform that moves... 
    Suggested
    Visa sponsorship

    Artie

    San Francisco, CA
    3 days ago
  •  ...move from experimenting with agents to using them reliably in production. That means solving challenging problems in cloud...  ...initiative, close relationships with customers, and exceptional engineering craft. We take ownership, learn quickly, and communicate directly... 

    AI Chopping Block

    San Francisco, CA
    4 days ago
  •  ...questions or complete a single turn. Our work brings together product, agent, and infrastructure capabilities across OpenAI. Together...  ...About the Role We're looking for a full stack product engineer to shape how people discover, direct, and collaborate with AI coworkers... 

    Triwill Group

    San Francisco, CA
    4 days ago
  • $200k - $250k

     ...About The Role This is a founding engineering role at an early-stage B2B SaaS startup building an AI-driven pricing and monetization platform. You'll own entire product modules end-to-end — from architecture through shipped UI — working directly with customers and... 
    Contract work
    Remote work

    Clera

    San Francisco, CA
    2 days ago
  • $140k - $200k

     ...Base pay range $139,999.00/yr - $200,000.00/yr Mission We’re looking for full stack Product Engineers to join our team building AthenaHQ, the leading platform powering global brands on AI Search. We’re looking for an engineer who enjoys owning products You’ll work with... 
    Full time

    AthenaHQ

    San Francisco, CA
    4 days ago
  •  ...Metaview is an applied AI lab building AI coworkers for recruiting teams. You will own end-to-end software from problem discovery to production adoption, with zero-to-one work and no fixed roadmap. This hands-on IC role requires shipping at least one bounded customer... 

    Metaview

    San Francisco, CA
    4 days ago
  • $230k - $300k

     ...companies in AI (Hugging Face, Groq, Perplexity and a bunch of stealth product teams pushing what’s possible with AI agents) They’re building the hyperscaler for AI agents , and looking for an engineer who wants to show the world what’s possible. What you’ll do: Build... 
    Full time

    AMIGOS

    San Francisco, CA
    4 days ago
  •  ...documents the way a human would, and make it possible to build products, train models, and automate processes at scale. We’ve grown...  ...z, Benchmark, and First Round Capital, and are hiring a Design Engineer. The Role As a Product Engineer, you'll own the development... 
    Work at office
    Local area

    Reducto

    San Francisco, CA
    4 days ago
  •  ...A leading AI systems company in San Francisco seeks a Sr. Product Engineer to shape product direction and build across the entire stack. The ideal candidate combines product intuition with technical skills, notably in React, Typescript, and Python. Responsibilities include... 

    Imbue, Inc.

    San Francisco, CA
    3 days ago
  •  ...Product Engineer LiteLLM is the world's most popular AI Gateway, trusted by companies like Adobe, Netflix, and NASA. We're building the next generation of infrastructure for AI applications-and now we're building our second product. We're looking for a Product... 
    Immediate start

    LiteLLM AI Gateway

    San Francisco, CA
    1 day ago
  •  ...Ando Engineering Opportunity Ando is a messaging platform where AI agents can take on work alongside human. We're rebuilding Slack from...  ...engineers who are excited by that challenge: building a product from first principles, shaping the future of how humans and AI... 
    Full time
    Work from home

    ASARI S.A de CV

    San Francisco, CA
    4 days ago
  •  ...Most engineering jobs start with a ticket. This one starts with a customer problem. At Metaview, you will talk directly to the people...  ...what happens next. There is no chain of handoffs between product, design, engineering, support, and the customer. The person closest... 
    Work at office
    Visa sponsorship
    Work visa

    Metaview

    San Francisco, CA
    2 days ago
  •  ...schools. Featured on Business Insider. You'll Own features end-to-end - interview customers every week and watch them use the product, and ship the feature they need by the next week Actually use the algorithms, data structures, and system design that you... 
    Full time
    Work at office
    Relocation

    Bild AI

    San Francisco, CA
    1 day ago
  •  ...Founding Product Engineer Weave (YC W25) is building the definitive platform for understanding and improving how engineering teams work. We believe the way engineering output is measured today is fundamentally broken and that modern AI can give teams a far more accurate... 
    Immediate start

    Weave, Inc.

    San Francisco, CA
    2 days ago
  • $195k - $350k

     ...Product Engineer San Francisco (Hybrid); San Mateo, CA (Hybrid) Eve is redefining legal technology for plaintiff law firms, and we're building the team that will take us there. We help firms handle more cases, recover more for clients, and grow with AI that works... 
    Temporary work
    Work at office
    Local area
    Flexible hours

    Eve

    San Francisco, CA
    2 days ago
  •  ...Product Engineer Our client makes safeguarding sensitive data for every application simple and seamless. Organizations, from startups to global brands, trust Nightfall's software platform and APIs to classify and protect sensitive data. As a Product Engineer you'll... 

    MDA Edge

    San Francisco, CA
    3 days ago
  •  ...and HOF Capital. The team is based in San Francisco and includes engineers, designers, and operators from Airbnb, Palantir, Pinterest, IMC...  ...my thoughts on the perfect candidate we're looking to join our product team: Product focused: There are a lot of features that... 

    Conversion Services

    San Francisco, CA
    2 days ago
  •  ...assess and monitor the novel risks introduced by AI in their products and across their assets and ecosystem. Our research has uncovered...  ...traditional tooling wasn't built to solve. We're hiring engineers across the stack to help us build the platform, detections, integrations... 

    PromptArmor

    San Francisco, CA
    1 day ago
  •  ...We're Hiring The First Engineer For Our New Product We're hiring the first engineer for our new product. You will own this from start to initial launch. Building the best APIs for realtime people and company data took us from 0 to $4M ARR in first 9 months while... 

    Crustdata (YC F24)

    San Francisco, CA
    4 days ago
  •  ...AirOps Product Engineer AirOps is the full-service platform for brand growth in the age of AI search. As consumers shift from traditional search engines to platforms like ChatGPT, Claude, and Gemini, the entire ruleset of growth is being rewritten. Buyers now rely... 
    Flexible hours
    Shift work

    Airops

    San Francisco, CA
    4 days ago
  • $160k - $200k

     ...About the job Founding Product Engineer About the Company Our client is a venture-backed startup building the next generation of revenue infrastructure for B2B AI companies, starting with intelligent deal pricing and quoting. They are replacing legacy tooling... 
    Full time
    H1b
    Visa sponsorship

    David Joseph and Company

    San Francisco, CA
    22 hours ago
  • $150k - $250k

     ...Product Engineer We're a small, dynamic team based in San Francisco, and we're looking for a product engineer to join us. In this in-person role, you'll have the opportunity to wear multiple hats, interact directly with our customers, and play a vital part in shaping... 
    Visa sponsorship

    Artie

    San Francisco, CA
    2 days ago
  •  ...About the job Product Engineer Job Description: Our client is seeking - a highly skilled and motivated Product Engineer to join our team in San Francisco or New York. As a Product Engineer, you will be responsible for designing, developing, and testing our... 

    UpCore Solutions

    San Francisco, CA
    22 hours ago
  •  ...Product Engineer We are looking for a Product Engineer with 2+ years of experience to join a fast-moving LegalTech startup transforming the U.S. immigration experience through AI. This is a backend-leaning, full-stack role where you will own meaningful product features... 
    Immediate start

    NxT Level

    San Francisco, CA
    4 days ago
  • $140k - $180k

     ...About the Role This is a founding product engineering role at an early-stage legal AI startup, where you will build core product features from the ground up alongside attorneys and AI engineers. You will set the engineering culture and standards for the team while owning... 
    Full time
    Contract work

    Clera

    San Francisco, CA
    1 day ago
  • $150k - $200k

     ...new class of intelligent, software-defined power infrastructure products leveraging a decade of advanced medium voltage Solid State...  ...our geographies. Role Summary: As a Senior Compliance Engineer , you will be a critical part of the product development process... 
    Full time
    Temporary work
    Local area
    Worldwide
    Shift work

    Amperesand

    San Francisco, CA
    1 day ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Product Engineer. Be the first to apply!