Senior Lead Scientist, Antibody Discovery & Innovation
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Merck & Co., Inc. in South San Francisco seeks a Principal Scientist to lead in vivo antibody discovery efforts, guiding strategies from hit identification to candidate selection. You will expand technology platforms, collaborate with therapeutic-area scientists, and mentor high-performance teams while advancing pipeline goals. This role emphasizes inclusive leadership, external scientific contributions, and timely delivery in a fast-paced, cross-functional environment. #J-18808-Ljbffr CamWebDir
- Merck & Co., Inc. in South San Francisco seeks a Principal Scientist to lead immunization-based antibody discovery strategies, driving platform innovations and cross-functional collaboration within Discovery Biologics. The candidate will oversee in vivo antibody discovery...Senior
$176.2k - $277.3k
...company. Our teams combine leading drug discovery capabilities and world-class... ...and experienced scientist in the role of Principal Scientist... ...expertise in immunization-based antibody discovery, including but... ...strategies encompassing operations, innovation, and externalization...SuggestedFull timeFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work- Merck & Co., Inc. in South San Francisco seeks a Senior Scientist to advance antibody discovery and automation in the Molecular Discovery group. You will lead automated liquid handling and HTS workflows, collaborate with cross‑functional teams, and drive high‑throughput...Senior
$168.1k - $312.3k
...It’s what drives us to innovate. To continuously... ...are transforming drug discovery and development. Roche... ...Intelligence (AI) to assist our scientists in both pRED and gRED... ...that accelerate antibody discovery. Our focus is... ...looking for a talented Senior Scientist who combines...SeniorLocal areaWorldwideRelocation package- Twist Bioscience seeks an exceptional R&D scientist in South San Francisco to lead protein sciences with antibody focus. You will be hands-on while shaping the technical roadmap, and later manage a team as the group grows. Expect to balance bench work with strategic design...Senior
- ...end-to-end within the Display Technologies group, designing selection strategies and turning campaigns into high-quality data for antibody design models. This high-ownership role emphasizes rigorous bench execution, experimental design, mentoring, and collaboration with...Senior
- Genentech, part of Roche, is seeking a Senior Scientist to advance AI-driven antibody design and developability assessment within gRED/pRED collaborations... ..., publication-quality research, and impact on real discovery challenges in a fast-evolving Biotech setting in California...Senior
$161.9k - $173.9k
Senior Scientist - Degrader Antibody Conjugate Cellular Nurix Therapeutics is a clinical... ...company focused on the discovery, development, and commercialization... ..., the next frontier in innovative drug design aimed at... .../no-go recommendations. Lead and influence a matrixed,...Senior$174.9k - $185.2k
Senior Scientist, Antibody Conjugation About the Role We are growing the team with a hands-on antibody conjugation scientist who will build this... ...capability inside an established, highly collaborative discovery organization and partner closely with medicinal chemistry,...Senior- ...manufacture, and deliver innovative medicines to help... ...transforming your career. Senior Scientist Experimental Protein Design for Target Discovery What You Will Do Lets... ...you will build and lead high-throughput platforms... ...minibinders and antibodies across diverse pre-discovery...SeniorFlexible hours
- ...is to discover and deliver innovative medicines and solutions that... ...and novel modalities, from discovery through human clinical... ...Innovation Group is seeking a Senior Scientist I to join a talented and collaborative... ...production of recombinant antibodies and complex biologics. This...SeniorTemporary work
$131.4k - $206.8k
...Description We are recruiting a Senior Scientist to support antibody generation and automation in our Molecular Discovery group located in South San... ..., group meetings, project leads, and cross‑functional... ...development, or implementation of innovative technologies that enable de...SeniorFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$134.84k - $240.78k
Senior Scientist Antibody Engineering August 2026 Position Summary: Join our innovative team at TCG Labs-Soleil as an antibody engineering expert... ...and motivated scientist to lead and advance our display-... ...mammalian display) to enhance discovery and screening capabilities....SeniorTemporary workFlexible hours- Collabera Inc. in South San Francisco, CA, seeks a Scientist II to support biologics drug discovery and engineering in a dynamic enterprise environment... ...vitro display technologies to identify and optimize lead antibodies, and contribute to data packages for proof-of-...
$124k - $155k
About the Role At Xaira, we're building antibody discovery engines that feed AI-driven design at scale. We're looking for an accomplished protein... ..., you'll help raise the group's level — mentoring associate scientists, setting technical standards, and partnering with...Flexible hours- ...strategies, tackling difficult targets, and turning campaigns into high-quality data for antibody design models. This high-ownership role runs campaigns, sets technical direction, mentors scientists, and collaborates with computational and engineering colleagues to scale data...
- TCG Labs-Soleil seeks a Senior Scientist, Bioanalytical Sciences to lead PK/ADA and biomarker assays across discovery to clinical development. The role demands strategic vision, hands-on expertise, and strong collaboration with cross-functional teams in a dynamic biotech...Senior
- ...drive strategy and oversee non-clinical ADME/PK studies across discovery and development. You will serve on multidisciplinary project teams... ...project leadership, and strong communication skills to inform senior stakeholders and regulatory discussions. #J-18808-Ljbffr RocheSenior
- TCG Labs-Soleil is seeking a Senior Scientist in Antibody Engineering to lead display-based antibody engineering and integrate AI-driven design with experimental... ...protein sciences, and in vitro teams to accelerate discovery and maturation of therapeutic antibodies. You will...
- Nurix is seeking an antibody conjugation scientist to build and validate bioconjugation chemistry for bench-scale experiments and scalable workflows. The role partners with medicinal, analytical, computational chemistry, and automation teams to move candidates toward study...
- Star Therapeutics in South San Francisco, CA, seeks a Senior Scientist II, Discovery Biology to lead discovery workstreams, design and execute hypothesis-driven studies, and mentor junior scientists. You will frame scientific questions, assess risks, and collaborate with...
- Nurix is seeking a Senior Scientist, Antibody Conjugation to build and own a new bioconjugation capability. You will develop robust chemistries,... ...move candidates from bench to study-ready material. You will lead method development, protocol transfer to liquid-handling...Senior
- AbbVie in South San Francisco is seeking a Senior Scientist I to join the Cell Line Development Innovation Group. You will develop next-generation CHO cell platforms for recombinant antibodies, driving expression optimization from vector design through cell line selection...Senior
- BioTalent is seeking a Scientist or Scientist II to lead preformulation activities across novel small molecule discovery programs. This is a highly hands-on role, with approximately seventy percent laboratory work and the opportunity to influence programs from early discovery...Senior
- Merck is seeking a Senior Scientist to join the Respiratory Biology Discovery group. The role focuses on target identification, validation, translational biology, and mechanism-of-action studies for chronic lung diseases, using primary airway/alveolar epithelial biology...Senior
- Twist Bioscience Corporation is seeking an R&D scientist/manager with deep cell biology and protein expression expertise to lead antibody-focused protein sciences. Initially hands-on while building a team and roadmap, the role blends bench work with strategic leadership...
- Addition Therapeutics, a South San Francisco biotechnology company, seeks a contract SRA/Scientist for Lipid Nanoparticle (LNP) discovery to design, produce, and optimize LNP formulations for preclinical experiments. The role involves hands-on formulation, characterization...SeniorContract work
- ...in South San Francisco seeks a Scientist/Senior Scientist in Structural Biology... ...across therapeutic areas. You will lead cryo-EM workflows, collaborate with discovery and engineering teams, and... ...to method development and tech innovation. The role combines hands-on structural...SeniorFlexible hours
- Genentech, a member of the Roche group, seeks a Senior Scientist to advance developability modeling and biophysical approaches for antibody design within the AIDD group of the Computational Sciences Center of Excellence. You will collaborate across gRED and pRED, translating...Senior
- Star Therapeutics in South San Francisco, CA seeks a Senior Scientist II, Discovery Biology. You will lead key experimental workstreams, develop integrated hypotheses, and mentor junior scientists to advance therapeutic opportunities. You will collaborate with senior leaders...Senior
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