Associate Scientist - Upstream Cell Culture

Job Description Summary Associate Scientist - Upstream Cell Culture #LI-Onsite Location: Durham, USA This role is based in Durham, USA. Novartis is unable to offer relocation support for this role. Please only apply if this location is accessible for you. The Technical Research & Development (TRD) Department drives the advancement of the Adeno-associated virus (AAV) and Lentiviral vector (LVV) production platform across multiple development sites and manages the development, scale-up, scale-down, transfer, optimization, and characterization of processes for the clinical manufacturing of Novartis cell gene therapy products. Job Description Major accountabilities: Designs and executes gene therapy upstream process development studies. Supports early development study projects and late-stage process characterization and scaling up studies. Analyses and interprets experimental data from process studies with strong statistical mindset. Conducts laboratory studies to enhance AAV and LVV manufacturing technologies, capabilities, and processes (such as media development, bioreactor fed-batch and perfusion process development, optimization and scale-up). Preforms experiments at different scales to support pre-clinical, clinical and commercial programs. Assists the evaluation and introduction of new technologies. Authors technical reports and presents results of development studies both internally and externally. Collaborate with cross-functional groups to coordinate studies. Other related duties as assigned. Essential Requirements: Experience with bioreactor operation including ambr® (15 & 250), bench-top bioreactor, pilot scale bioreactor. Proficient in statistical analysis principles and software. Working knowledge and experience with Design of Experiment (DoE). Ability to analyze data to make date-driven decisions and further progress development strategies. Knowledge of viral gene therapy and previous experience with AAV process development is preferred. Excellent team player with good communication skills. Novartis Compensation Summary: The salary for this position is expected to range between $73,500.00 - $136,500.00 USD Annual per year. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves. To learn more about the culture, rewards and benefits we offer our people click here. EEO Statement: The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. Accessibility and reasonable accommodations The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to View email address on click.appcast.io or call View phone number on click.appcast.io and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Salary Range $73,500.00 - $136,500.00 Skills Desired Materials Science, Process Simulation Improving the lives of people living with disease takes more than innovative science. It takes a focus on the needs of people and a community committed to meeting them. It takes a team of people like you. Working together. Learning together. Thriving together. Discover how you can join us in changing people’s lives. Novartis is aware of employment scams which make false use of our company name or leader’s names or recruiter’s names to defraud job seekers. 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