HR Business Partner

Quetzal Therapeutics is a biopharmaceutical company focused on the development of treatment for rare diseases including hematologic malignancies. The company’s lead product is QTX-2101, a novel paradigm for treating patients with Acute Promyelocytic Leukemia (APL). The company initiated a Phase III clinical trial in Dec 2025 , with enabling activities ongoing. Quetzal is also developing a pre-clinical asset QTX-2102, an advanced, next-generation antifungal and antiparasitic therapy designed to enhance efficacy while minimizing toxicity. Our mission is to push the boundaries of treatment possibilities, delivering hope and life-changing solutions to those who need them most. About the Role We are seeking a knowledgeable, proactive HR Business Partner to support key people initiatives across the employee lifecycle. Reporting to the Chief Human Resources Officer, this full-time role partners closely with leaders and employees to drive recruiting, onboarding, benefits administration, training, employee relations, performance management, and compliance. The ideal candidate is detail-oriented, collaborative, and committed to building a positive, compliant, and high-performing workplace. This role is based in Lincolnshire, Illinois, with remote flexibility for the right candidate. Why Join Us This is an opportunity to play a visible, hands‑on role in shaping the employee experience and strengthening HR operations across the organization. You will partner with leadership, influence key people processes, and help build a workplace culture grounded in compliance, collaboration, and continuous improvement. What You’ll Do Lead full‑cycle recruitment, including sourcing, interviewing, reference checks, and offer coordination Partner with hiring managers to identify talent needs and build pipelines of qualified candidates Ensure recruiting practices comply with applicable laws and internal policies Coordinate and lead onboarding to create a smooth, engaging transition for new hires Manage offboarding processes and conduct exit interviews to capture insights and support smooth transitions Ensure timely, accurate completion of onboarding and offboarding documentation Offer assistance to our external HR partner in administering employee benefits programs, including enrollments, changes, and employee education Assist our external HR partner in serving as a liaison with benefits providers and respond to employee questions Assist as needed with open enrollment process and maintain compliance with applicable benefits regulations Coordinate employee training initiatives, including compliance and role‑specific learning where applicable Assist external HR partner in tracking participation in and completion of required training programs where applicable Support leaders in identifying and implementing employee development opportunities Coordinate and track annual and interim performance review processes Partner with managers to support timely evaluations and meaningful development plans Help align performance outcomes with organizational goals and compensation planning Provide guidance to employees and managers on HR policies, practices, and procedures Address employee concerns, support investigations, and help resolve workplace issues appropriately Promote a respectful, compliant, and collaborative workplace culture Partner with external HR partner to maintain and update the employee handbook and HR policies Ensure compliance with federal, state, and local employment laws, including FLSA, FMLA, EEO, and ADA requirements, as applicable Assist with internal audits and maintain documentation to support compliance efforts Maintain accurate, confidential HR records, including personnel files, I‑9s, training logs, and benefits documentation Ensure data integrity within HR‑related systems Generate reports and support audits, compliance reviews, and other HR inquiries as needed Required Qualifications Bachelor’s degree in Human Resources, Business Administration, or a related field, or equivalent practical experience 3–5 years of progressive HR experience Strong working knowledge of HR best practices and employment law Exceptional organizational, communication, and interpersonal skills Experience with HR systems, applicant tracking systems, and proficiency in Microsoft Office Preferred Qualifications HR certification such as PHR or SHRM‑CP Previous experience with Rippling HRIS Experience supporting a family‑owned business #J-18808-Ljbffr Quetzaltx