Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal Software Development Engineer

Metabolon

Overview Metabolon is seeking an experienced and driven Principal Software Development Engineer to join our team. This is a full-stack role, requiring expertise across both back-end and front-end technologies to deliver end-to-end solutions. In this role, you will lead engineering efforts across multiple teams, guiding the design, architecture, and deployment of critical systems. This role requires a strategic, hands-on technical leader with a focus on scalability, performance, and effective system architecture. You will act as a trusted advisor, helping teams and managers overcome complex challenges and align technical decisions with business objectives. Responsibilities Technical Excellence Lead the design, implementation, and evolution of enterprise-level systems that are resilient, scalable, and cost-effective. Ensure code quality through exemplary practices in code clarity, organization, error handling, and documentation. Stay current with emerging technologies, bringing in relevant knowledge to help improve company-wide engineering practices. Innovation & Simplification Drive innovation while simplifying complex systems and processes, consistently finding straightforward solutions to multifaceted challenges. Contribute to the company’s intellectual property through original ideas, tools, or technologies that elevate the organization’s technical capabilities. Strategic Influence Continuously bring a business-centric perspective to technical decisions, balancing innovation with practicality and cost-effectiveness. Act as a key contributor to your department's strategic planning, impacting both the technical roadmap and organizational growth. Influence cross-functional initiatives, contributing to the broader technology and product strategy. Technical Leadership Provide engineering leadership across multiple teams, offering guidance on complex technical challenges and system architectures. Oversee design reviews for critical projects within the department and participate in company-wide technology reviews. Establish and maintain high standards for performance, scalability, and robustness in system design. Mentorship & Development Mentor engineers on technical and professional growth, fostering a culture of continuous learning and improvement. Collaborate with managers to support career development pathways for team members, focusing on skill development and knowledge sharing. Qualifications BA/BS degree in Computer Science, Engineering, or a related STEM field. 7+ years of experience in software engineering, with a proven record in architecting and delivering large-scale systems. Strong foundation in .NET, Python, AWS, Django, and a front end JS technology such as React/Angular, or comparable technologies. Experience leveraging modern coding agents and generative AI technologies to improve products, automate workflows, and accelerate engineering productivity. Experience in providing technical leadership, with a demonstrated ability to mentor and influence at an organizational level. Exceptional communication skills, with the ability to translate complex technical concepts into clear, actionable insights for non-technical stakeholders and cross-functional teams. Strong problem-solving skills with an emphasis on systems design, scalability, and performance. Proven ability to navigate ambiguity, quickly develop expertise in unfamiliar areas, and lead the resolution of complex technical and operational challenges. Demonstrated growth mindset, intellectual curiosity, and commitment to continuous learning, with a track record of adapting to evolving technologies and business needs. About Us Metabolon, Inc., is the global leader in revealing biological insights on disease state and physiological reactions in the present time through metabolomics. Leveraging one of the world’s most diverse and rich patient data sets, Metabolon is equipped to deliver biologically relevant evidence to address some of the most difficult and pressing questions in the life sciences. Every day, our work is helping to accelerate research and product development success in the biopharma, population health, consumer products, agriculture, wellness, and academic research sectors. Metabolon was founded in 2000 and is headquartered in Research Triangle Park, North Carolina with an international headquarters in Germany. For more information, please visit is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other protected status prohibited under Federal, State, or local laws. All employment decisions are based on valid job‑related requirements. #J-18808-Ljbffr

Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the Principal Software Development Engineer in Morrisville, NC vacancy
  •  ...for a high energy, strategic, and fast-paced position as a Principal Software Engineer? Join Relias, the company changing lives throughout the...  ...growth aligned with evolving business needs Multiple development program options - leadership development, professional development... 
    Suggested
    Live in
    Work at office
    Work from home
    Flexible hours

    Bertelsmann

    Morrisville, NC
    6 days ago
  • $107.5k - $204.5k

     ...world-class operations and investments in research and development, we offer capabilities and opportunity no one else...  ...Aerospace Resilient Connectivity Products (RCP) Engineering is seeking Principal DevSecOps Software Engineer to join a dedicated DevSecOps team that is... 
    Suggested
    Temporary work
    Work experience placement
    Work at office
    Remote work
    Relocation
    Flexible hours

    RTX

    Morrisville, NC
    2 days ago
  • $206.4k - $276.7k

     ...is a global organization of engineers, product developers, designers...  ...our Research and Advanced Development teams whose focus is in the...  ...design video algorithms and software workflows for the purposes of...  ...platform. As a domain focused Principal Engineer, you are expected... 
    Suggested

    The Walt Disney Studios

    Morrisville, NC
    5 days ago
  • $100.3k - $150.5k

    Principal/Sr Principal Software Engineer (*Active TS/SCI required) Requisition ID: R10189875 Location: Morrisville, North Carolina, United States of...  ...engineer to support Application Management (AM) Software Development. What you’ll get to do : As a Software Engineer on... 
    Suggested
    Work experience placement
    Relocation package
    Monday to Thursday
    Shift work

    Northrop Grumman

    Morrisville, NC
    2 days ago
  • $170.77k - $281.77k

     ...Primary Job Responsibilities Collaborate with Staff Engineers, Engineering, Product Management, and User Experience...  ...customer needs and use cases. Create robust AI/ML software tools to enable AI Application development and contribute to a healthy open source community. Develop... 
    Suggested
    Permanent employment
    Full time
    Contract work
    Work experience placement
    Work at office
    Remote work
    Flexible hours

    Red Hat

    Raleigh, NC
    1 day ago
  •  ...Division: Ticketmaster, Payments. Line manager: VP Marketplace Engineering. Contract terms: Permanent, full time. Overview We’re seeking...  .... Required Technical Skills 7+ years of professional C++ development experience in production environments. Modern C++ fluency and... 
    Permanent employment
    Full time
    Contract work
    Local area
    Remote work
    Flexible hours

    Live Nation Worldwide

    Raleigh, NC
    1 day ago
  • $124k - $156k

     ...Role Overview As a Principal Software Engineer, you will leverage the latest AI Development tools to amplify engineering output, while also building agentic capabilities into our enterprise SaaS and desktop applications. You will be an AI evangelist on the team—ensuring... 

    insightsoftware

    Raleigh, NC
    3 days ago
  • $150k - $300k

     ...The Role As Principal Software Engineer for a new product within Veeva, you will be a founding member of a team building our next major AI-driven...  ...companies manage safety, regulatory, and clinical development. You will influence and help grow a codebase and engineering... 
    Local area
    Flexible hours

    Veeva Systems

    Raleigh, NC
    1 day ago
  •  ...Principal Software Engineer About Prometheus Group: Prometheus Group is a team of self-starters centered on being resourceful, accountable...  ...Principal Software Engineer to join our innovative development team. The ideal candidate will be a software craftsman, and... 
    Temporary work
    Casual work
    Immediate start

    Prometheus Group

    Raleigh, NC
    4 days ago
  • $165k - $185k

     ...NIC MAP is looking for a Principal Software Engineer to join our engineering team. You will design, build, and maintain the software that powers...  .... Advanced proficiency in C#, .NET, and full stack development. Strong front-end experience across Angular, React,... 
    Work at office
    Remote work
    Work from home

    NIC MAP

    Raleigh, NC
    4 days ago
  •  ...s model hosting Platform team is looking for an experienced software engineer to design, build and contribute to our AI/ML model hosting platform...  ...This role is focused on end-to-end Cloud Native Application Development with Python. Proven expertise in developing secure and... 
    Work experience placement
    Remote work
    Flexible hours

    Ally

    Raleigh, NC
    1 day ago
  • $99.6k - $223.4k

     ...operational needs. You care about building usable, reliable software that helps engineering and operations teams reason about complex physical...  ...modeling and infrastructure lifecycle management. Drive development of core platform capabilities, including topology... 
    Temporary work
    Flexible hours

    Oracle

    Raleigh, NC
    2 days ago
  • $117.1k - $187.3k

     ...successful technology leader, you will build and lead remote software engineering organizations using agile principles to architect and...  ...between technical composing and product building for software development teams that work on content workflow automation, application... 
    Work experience placement
    Live in
    Local area
    Remote work
    Worldwide

    Cengage Group

    Raleigh, NC
    2 days ago
  •  ...Principal Software Engineer This is a hybrid position that requires a minimum of 3 days per week in our Raleigh NC office. AKC is seeking...  ...Leadership and Delivery ~10+ years of software development experience, including leading projects and managing or mentoring... 
    For contractors
    Work at office
    3 days per week

    American Kennel Club

    Raleigh, NC
    2 days ago
  • Principal Software Engineer/Developer Published: Jun 10 ID: 2130513 Location: Durham, NC Job Description Develops core digital analytics capabilities and enhances the usage of digital data across the organization. Enhances the digital analytics and digital Voice of Customer... 

    Habitat For Humanity Of Durham

    Durham, NC
    1 day ago
  • Reports to Chief Engineer - Charging Hardware. This role requires a full-time onsite...  ...tomorrow. Position Summary The Principal Charging Software Engineer owns charger software end-to...  ...architecture, and the full software development lifecycle (SDLC) with our charger... 
    Permanent employment
    Full time

    Valid8 Financial, Inc.

    Raleigh, NC
    5 days ago
  •  ...of the worldâs most influential companies. As a Senior Principal Software Engineer at JPMorganChase within the Consumer & Community Bank Technology...  ...quo, innovate for business impact, lead the strategic development behind new and existing products and technology... 
    Bank staff

    慨正橡扯

    Raleigh, NC
    5 days ago
  • $110k - $180k

    ## Principal - Software Engineer .### General informationCareer areaTechnologyWork Location(s)500 Woodward Avenue, MI, 601 S. Tryon Street, NCRemote...  ...with automation engineering, workflow orchestration, API development and integration, and cloud-native solution development.*... 
    Full time
    Temporary work
    Part time
    Work experience placement
    Work at office
    Remote work
    Relocation package
    Flexible hours

    Ally Financial Inc.

    Raleigh, NC
    1 day ago
  • Principal Software Engineer Jobs in USA 2026 with Visa Sponsorship Principal Software Engineer Jobs in USA 2026 with Visa Sponsorship Step into...  ...of frontend architecture and modern web application development. Based in Raleigh, the role offers visa sponsorship for qualified... 
    Visa sponsorship

    NewsNowGh

    Raleigh, NC
    1 day ago
  • $206.4k - $276.7k

    Principal Software Engineer Job ID: 10149993 Location: San Francisco, California; Morrisville, North Carolina, United States Business: Disney...  ...5, 2026 Job Summary You will be focused on research and development for future generation image and video coding especially... 
    Local area

    The Walt Disney Company

    Raleigh, NC
    2 days ago
  • $151.51k - $249.95k

    Red Hat Engineering is looking for a Principal Software Engineer to join our OpenShift team, building the premier Kubernetes platform. Responsibilities Lead the design and development of software solutions for features that span multiple subsystems. Advocate for customer... 
    Permanent employment
    Full time
    Flexible hours

    Red Hat, LLC

    Raleigh, NC
    2 days ago
  • ## Principal Software Engineer/DeveloperApplylocations: Durham, NCtime type: Full timeposted on: Posted Todaytime left to apply: End Date: July...  ...initiatives. Analyzes and recommends changes in project development policies, procedures, standards, and strategies to development... 

    Soteria Reinsurance Ltd.

    Durham, NC
    2 days ago
  • $150k - $300k

    Veeva Systems, Inc. is seeking a Principal Software Engineer to develop and guide scalable enterprise applications. You will mentor engineers,...  ...technology. Required qualifications include 12+ years in software development, especially in Java, and a proven ability to design high-... 
    Flexible hours

    Veeva Systems, Inc.

    Raleigh, NC
    16 hours ago
  • $151.51k - $249.95k

    About the Job Red Hat Engineering is looking for a Principal Software Engineer to join us to continue making OpenShift the premier Kubernetes platform....  ...you will do Technical Impact: Leads the design and development of software solutions for features that cross multiple... 
    Permanent employment
    Full time
    Work experience placement
    Remote work
    Flexible hours

    Red Hat, Inc.

    Raleigh, NC
    2 days ago
  • $144.2k - $288.4k

    Position Summary As a Principal Software Engineer, you will define and drive the technical direction for modern, cloud‑native applications built...  ...Qualifications 10+ years of professional software development experience, including hands‑on Agile delivery of enterprise... 
    Hourly pay
    Full time
    Temporary work
    Local area

    Hispanic Alliance for Career Enhancement

    Raleigh, NC
    2 days ago
  •  ...as a member of the Card Applications & Development team, responsible for developing advanced...  ...analysts, stakeholders, and other engineering teams to guide the overall technical strategy...  ...Education: Bachelor's degree in Software Engineering, Computer Science, Information... 

    State Employees' Credit Union

    Raleigh, NC
    16 hours ago
  •  ...institutions, you’ve come to the right place. As a Senior Principal Software Engineer at JPMorgan Chase within Consumer & Community Banking...  ...status quo, innovate for business impact, lead the strategic development behind new and existing products and technology... 

    慨正橡扯

    Raleigh, NC
    5 days ago
  • ## Principal Mainframe Software Engineer (Java, COBOL, DB2/VSAM)Applylocations: Durham, NCtime type: Full timeposted on: Posted Todayjob requisition...  ...Expertise and Skills You Bring*** 8+ years of software development experience in business critical, enterprise-wide applications... 
    Shift work

    Soteria Reinsurance Ltd.

    Durham, NC
    16 hours ago
  • $124k - $156k

    Principal Software Engineer - Broker Applications Team As a Principal Software Engineer on the Broker Applications team, you will serve as the...  ...organizational minimums for your team. Model an agentic development mindset - integrating AI tooling into your own daily workflow... 
    Work experience placement

    insightsoftware, LLC

    Raleigh, NC
    5 days ago
  • $150k - $300k

    Veeva Systems, Inc. is seeking a Principal Software Engineer to work on an AI-driven platform transforming Life Sciences management. You will guide feature implementation, collaborate on designs, and mentor junior engineers. The ideal candidate has over 12 years of production... 

    Veeva Systems, Inc.

    Raleigh, NC
    16 hours ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal Software Development Engineer. Be the first to apply!