Associate Director, Clinical Pharmacology

Associate Director, Clinical Pharmacology United States - Massachusetts - Cambridge United States - Connecticut - Groton United States - Pennsylvania - Collegeville United States - New York - New York City Exciting opportunity in Clinical Pharmacology! Our Clinical Pharmacology Team is looking for an Associate Director to support the portfolio in Internal Medicine. The role focuses on the innovative use of MIDD for efficient drug development and robust decision making. ROLE RESPONSIBILITIES Act as Clinical Pharmacology representative on Clinical Sub Team, Development Team and other multifunctional teams as appropriate. Provide expertise, leadership, and deliverables of clinical pharmacology for the assigned projects within sphere of influence. Design and execute clinical pharmacology plans and implement best practices on project teams. Work closely with other disciplines to ensure sufficient preclinical PK/PD knowledge underwrites safe human administration and establishes the structure of a predictive model prior to FIH. Plan and oversee clinical pharmacology aspects at the project level (clinical development plan, implementation and interpretation of PK/PD analyses, PK/immunogenicity/biomarker measurement strategies, etc.). Plan and oversee study level activities including protocol authoring, clinical phase oversight, and reporting. Ensure appropriate dose‑range finding strategies with clinicians and statisticians to identify optimal doses and dosage regimens in patients. Ensure appropriate design and implementation of End‑to‑End MIDD plan that conforms with best practices. Use innovative analytical methods to integrate knowledge of PK, PD, patient characteristics and disease states to optimize doses, dosage regimens and study designs. Provide End‑to‑End clinical pharmacology contributions to regulatory documents (briefing documents, regulatory queries, investigator’s brochures, IND, NDA/MAA, etc.). Develop new methodologies through internal and/or external collaborations with leading experts. Coach less experienced colleagues and team members. Stay abreast of literature, regulatory guidelines, and internal guidances and SOPs. Influence external environment through publications, presentations, and representation at scientific societies and industrial consortiums. QUALIFICATIONS Demonstrated broad leadership experience, influencing and collaborating with peers, and coaching teams. Strong quantitative skills and expertise (mechanistic PK/PD modeling, systems pharmacology, literature meta‑analyses, population modeling, clinical trial simulations using NONMEM, R, etc.). M.D./Ph.D., or equivalent training/experience in pharmacokinetics, pharmacometrics, clinical pharmacology, engineering, or related discipline. 1+ year industry experience in clinical pharmacology and/or clinical PK/PD and/or pharmacometrics/systems pharmacology. 5+ years industry experience in clinical pharmacology and/or clinical PK/PD and/or pharmacometrics/systems pharmacology. Intimate knowledge of drug development and experience applying quantitative pharmacology approaches to knowledge integration. Excellent written and verbal communication skills and demonstrated presentation skills. Ability to attend global meetings periodically across different time zones. OTHER JOB DETAILS Eligible for Relocation Package: Yes Eligible for Employee Referral Bonus: Yes Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on‑site an average of 2.5 days per week or more as needed. The annual base salary for this position ranges from $139,100.00 to $231,900.00. In addition, the position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 17.5% of the base salary, and eligibility to participate in the share‑based long‑term incentive program. Comprehensive benefits are offered, including a 401(k) plan with matching contributions, paid vacation, holidays, personal days, caregiver/parental and medical leave, and health benefits including medical, prescription drug, dental, and vision coverage. For details see Pfizer Candidate Site – U.S. Benefits. Relocation assistance may be available based on business needs and eligibility. Candidates must be authorized to be employed in the U.S. by any employer. U.S. work visa sponsorship (e.g., TN, O‑1, H‑1B) is not available for this role now or in the future. SUNSHINE ACT Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. If you are a licensed physician who incurs recruiting expenses reimbursed by Pfizer, your name, address and amount of payments will be reported. Please contact your Talent Acquisition representative for questions. EEO & EMPLOYMENT ELIGIBILITY Pfizer is committed to equal opportunity in employment without regard to race, color, religion, sex, sexual orientation, age, gender identity, gender expression, national origin, disability, or veteran status. Pfizer complies with applicable nondiscrimination laws and work authorization and employment eligibility verification requirements. Pfizer is an E‑Verify employer. This position requires permanent work authorization in the United States. #J-18808-Ljbffr