Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior Data Engineer

Xenon7

Location: Indianapolis, IN Metro (Hybrid / 3-Day Onsite) (Open to Regional/EST Candidates with Onsite Travel)

Contract Type: Contractor Full-Time / Enterprise Project Engagement (Outsourced via Xenon7)

About Xenon7

Where elite tech talent meets world-class opportunities! At Xenon7, we work with leading enterprise clients and innovative startups on high-impact projects across Data, AI, Cloud, and Software Engineering. Our expertise in AI solution architecture and specialized technical talent allows us to partner with enterprise leaders on transformative initiatives, driving innovation and business growth.

Job Summary

We are seeking a Senior Data Engineer with extensive experience in data architecture and platform engineering to drive data initiatives for a top-tier life sciences client. This role sits at the critical intersection of scientific research informatics, clinical data systems, and manufacturing process engineering.

In this position, you will own the architectural vision and hands-on execution of scalable data platforms and pipelines. You will bridge complex data domains—from small and large molecule research, genomics, and clinical trial datasets to active pharmaceutical ingredient (API) manufacturing processes, batch data, and industrial control systems. Operating in a 3-day onsite hybrid capacity in Indianapolis, you will collaborate directly with process engineers, clinical scientists, and platform teams to build high-performance data infrastructure that accelerates drug discovery and manufacturing operations.

Key Responsibilities
Scientific & Clinical Data Platform Architecture
  • Design, build, and maintain production-grade data pipelines and architecture tailored for scientific, clinical trial, and research informatics data (small/large molecule, genomics, proteomics, LIMS).
  • Structure complex, multi-modal clinical and scientific datasets to enable advanced analytics, enterprise reporting, and downstream machine learning models.
Process Engineering & Manufacturing Integration
  • Ingest, harmonize, and model operational technology (OT) and manufacturing process datasets, including API manufacturing pipelines, batch processing data, MES, SCADA, and OSIsoft PI systems.
  • Unify disparate laboratory and facility data pipelines into centralized, highly available enterprise data platforms.
Enterprise Data Engineering & Compliance
  • Build robust ETL/ELT pipelines using modern cloud platforms (Databricks, Snowflake, AWS/Azure), PySpark, and SQL.
  • Ensure all data pipelines and platform integrations strictly adhere to enterprise governance, data residency, and GxP regulatory standards within a heavily monitored environment.
Technical Leadership & Domain Alignment
  • Partner directly with process engineers, chemical engineering leads, and research informatics directors to translate operational friction into robust technical specifications.
  • Establish engineering best practices, data modeling standards, and pipeline monitoring frameworks across the enterprise data stack.

Requirements

Experience & Mindset
  • Experience: Senior-level proficiency (10–20+ years) in software development, data platform architecture, and complex ETL/ELT engineering.
  • Domain Adaptability: Demonstrated ability to engineer data pipelines across non-standard, highly specialized domains (e.g., transition between process/chemical engineering data and clinical/scientific research informatics).
  • Location & Work Auth: Must hold unrestricted US Work Authorization (no sponsorship available) and be able to work 3 days per week onsite in the Indianapolis, IN area.
  • Culture & Communication: Exceptional problem-solving mindset, strong adaptability, and the ability to articulate complex technical architecture to cross-functional engineering teams.
Must-Have Technical Stack
  • Languages & Frameworks: Advanced Python, PySpark, and expert-level SQL.
  • Data Platforms: Hands-on expertise with Databricks, Snowflake, or AWS/Azure enterprise data ecosystems.
  • Orchestration & ETL: Extensive experience with Airflow, dbt, Spark, and enterprise data orchestration engines.
  • Data Pipelines: Proven track record building streaming and batch data architectures via REST APIs, message brokers, and database integrations.
Domain Competency (Scientific & Process Focus)
  • Deep exposure to either scientific/clinical informatics (CDISC/SDTM, LIMS, clinical trials, multi-omics) OR chemical/process engineering data (API manufacturing, batch data, SCADA, MES, OSIsoft PI).
Nice-to-Haves & Certifications
  • Academic background in Chemical Engineering, Bio-process Engineering, Computer Science, or a related STEM discipline.
  • Direct experience working inside regulated GxP environments in the Life Sciences or Specialty Chemicals sectors.
  • Certifications: Databricks Certified Data Engineer Senior/Professional, Snowflake SnowPro Core/Advanced, or AWS Data Engineer Associate/Professional.
What This Role Is NOT
  • Not a pure Data Scientist or ML Researcher: You will not be building or training machine learning models; you are designing and scaling the underlying data architecture, pipelines, and platform infrastructure.
  • Not a non-coding Architect: This is a 100% hands-on engineering lead role requiring direct pipeline construction and technical execution.
  • Not a Fully Remote Position: This role requires a steady hybrid commitment of 3 days onsite per week at the client site in Indianapolis.
Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the Senior Data Engineer in West Lafayette, IN vacancy
  •  ...Senior Data Engineer Location: Indianapolis, IN Metro (Hybrid / 3-Day Onsite) (Open to Regional/EST Candidates with Onsite Travel) Contract Type: Contractor Full-Time / Enterprise Project Engagement (Outsourced via Xenon7) About Xenon7 Where elite tech talent... 
    Senior
    Full time
    Contract work
    For contractors

    Xenon Seven

    West Lafayette, IN
    3 days ago
  • Overview Job Title: Data Acquisition Hardware Engineer Full time (Test Lab Environment) Responsibilities Support and maintain data acquisition hardware systems used in product testing and validation activities. Build, modify, and troubleshoot electrical wiring harnesses... 
    Suggested
    Full time
    Internship

    ARi

    Lafayette, IN
    3 days ago
  •  ...and innovative startups on high-impact projects across Data, AI, Cloud, and Software Engineering. Our expertise in AI solution architecture and specialized...  ...business growth. Job Summary We are seeking a Senior Machine Learning Engineer with extensive experience in... 
    Senior
    Full time
    Contract work
    For contractors
    3 days per week

    Xenon7

    West Lafayette, IN
    2 days ago
  • Purdue For Life Foundation is seeking a seasoned development professional to lead major gift initiatives, build donor relationships, and drive fundraising campaigns. This role requires regular travel, evening/weekend commitments, and collaboration across university partners...
    Senior
    Weekend work
    Afternoon shift

    Purdue for Life Foundation

    West Lafayette, IN
    1 day ago
  •  ...OverviewA fast-growing, innovation-driven food company is seeking a Senior Product Developer to join its Research & Development team. This...  ...formulations, specifications, and test protocolsPerform data analysis, root cause investigations, and implement corrective actions... 
    Senior
    Work at office

    DSJ Global

    Lafayette, IN
    4 days ago
  •  ...Job Title Job Description: Identify valuable data sources and automate collection processes Undertake preprocessing of structured...  ...Education Requirement: Bachelors in Computer Science, Engineering or relevant field; graduate degree in Data Science or another... 
    Full time
    H1b
    Immediate start

    SynergisticIT

    West Lafayette, IN
    4 days ago
  •  ...Senior Project ManagerWest Lafayette, Indiana, United StatesMaintains a dual focus on practice-related services (senior-level guidance...  ...elevated billing issues when they arise. - Integrates financial data for multiple projects. - Accurately forecasts revenue, profitability... 
    Senior

    DHD Consulting

    West Lafayette, IN
    5 days ago
  • Comfort Systems USA is seeking an experienced Project Manager to lead large electrical construction projects in Lafayette, Indiana. This is a pivotal role to manage complex projects valued between $30M and $50M+, ensuring financial success and exceptional client satisfaction...
    Senior

    Comfort Systems USA

    Lafayette, IN
    2 days ago
  •  ...The Senior Tax Accountant is responsible for accounting tasks associated with the maintenance and preparation of tax records and tax returns. Outline of duties: Prepares federal, state, and/or local income and property tax returns and related statements. Maintains records... 
    Senior
    Local area

    Subaru of Indiana Automotive

    Lafayette, IN
    5 days ago
  • $16.75 - $17 per hour

    Hourly rate ranges from $16.75 - $17.00 per hour and is dependent upon qualifications and experience. Benefits Company Paid Sick Time Paid Vacation Time Paid Holidays Bereavement Pay Jury Duty Pay Contest Prize Awards 401K Plan with Company Match Medical/Dental/Vision ...
    Senior
    Hourly pay
    Local area

    Spencer Gifts

    Lafayette, IN
    5 days ago
  • A leading electrical contractor is seeking a Foreman Electrician to oversee installations and lead a team of electricians at various sites across the southeastern United States. The ideal candidate will have 7-10 years of experience in electrical construction, strong leadership...
    Senior
    For contractors

    Comfort Systems USA

    Lafayette, IN
    1 day ago
  •  ...on the link below to learn what our employees have to say about Evonik:://careers.evonik.com/en/about/meet-the-team/The Senior Automation Engineer - SIS provides support to Tippecanoe production and support areas through applied control theory and process automation design... 
    Senior
    Full time
    Local area
    Flexible hours

    Evonik Services

    Lafayette, IN
    2 days ago
  •  ...Senior Formulation Scientist (Full-time) Are you ready to be at the forefront of agricultural innovation? AgXelerators Inc. is a bold...  ...Qualifications: PhD or Master’s degree in chemistry, chemical engineering, material science or related field. 5+ years of experience in... 
    Senior
    Full time
    Flexible hours

    AgXelerators, Inc.

    West Lafayette, IN
    5 days ago
  • Job SummaryThe Senior Director, Research Support and Financial Management will lead and develop agile and responsive research support for...  ...management reports utilizing central databases to gather data.What We're Looking For:Required:Education and Experience:Bachelor... 
    Senior
    Immediate start
    Visa sponsorship
    Work visa

    Purdue University

    West Lafayette, IN
    3 days ago
  •  ...Senior Manufacturing Engineer – Indiana Our growing manufacturing client, located in north-central Indiana, is seeking a Senior Manufacturing Engineer to play a key role in the design, planning, and startup of a brand-new manufacturing facility. This role will lead... 
    Senior
    For contractors

    Management Recruiters

    Lafayette, IN
    2 days ago
  •  ...technology tasksRESPONSIBILITIESProcess Optimization & Continuous Improvement: Provide hands-on process engineering support for established operations by analyzing performance data, identifying inefficiencies, and driving continuous improvement initiatives to enhance... 
    Senior
    Full time
    Temporary work
    Local area

    Evonik Services

    Lafayette, IN
    14 hours ago
  • $19.57 - $34.15 per hour

     ...Senior TechnicianThe Senior Technician position requires your talent and technical expertise to diagnose drivability and electrical systems, while using your leadership and mentoring skills in driving a team toward increased customer care and satisfaction.Pay Range: $... 
    Senior
    Daily paid
    Minimum wage
    Price work
    Temporary work
    Local area

    Bridgestone Americas

    Lafayette, IN
    1 day ago
  •  ...The Senior Brand Designer leads the strategy and execution of high-quality visual storytelling that elevates Purdue Federal Credit Union’s brand. This role is grounded in advanced graphic design expertise to support marketing campaigns, member education, social media,... 
    Senior

    Purdue Federal Credit Unio

    West Lafayette, IN
    2 days ago
  • $40.34 - $41.34 per hour

     ...determining final compensation, we take into consideration: skillset, job scope, knowledge, prior experience, cost of living, market data, budget availability, and other factors as permitted by law.Pay range for this position is: $40.34 - $41.34/hour.In addition to... 
    Senior
    Local area
    Rotating shift

    Tate & Lyle

    Lafayette, IN
    15 hours ago
  •  ...is seeking an experienced and strategic Senior Production Scheduler to lead production planning...  ...management, manufacturing, supply chain, engineering, purchasing, and customer service teams....  ...proficiency in Microsoft Excel and data analysis. Strong communication and cross... 
    Senior

    Aux Partners

    Lafayette, IN
    2 days ago
  • $82.56k - $87.72k

     ...Senior Network Engineer City: West Lafayette Job Description: Job Summary This senior level network engineer is...  ...campus network infrastructure (e.g. Routing, Optical networks, Data Centers, Access Networking, Wireless, Firewalls, VPN... 
    Senior
    Local area
    Weekend work
    Afternoon shift

    Purdue University

    West Lafayette, IN
    2 days ago
  • $73k

     ...Job Summary As a Senior Content Writer with Purdue University’s award-winning in-house marketing agency, Purdue Brand Studio, you will serve as a creative leader, shaping the voice of one of the nation’s most respected universities. Through emotive storytelling and strategic... 
    Senior

    Purdue University

    West Lafayette, IN
    5 days ago
  • Description Who We Are Join White Lodging - a hospitality company operating premium hotels, rooftop bars, and restaurants in top U.S. cities. We're hiring an experienced line cook who is ready to lead in a fast-paced kitchen environment and mentor...
    Senior
    Full time
    Apprenticeship
    Flexible hours
    Shift work

    White Lodging

    West Lafayette, IN
    2 days ago
  • $23.47 - $32.65 per hour

     ...Senior Plumber City: West Lafayette Job Description: What You'll be Doing: Provide plumbing construction and maintenance services for the Birck Nanotechnology Center, a highly specialized facility that supports advanced research. The building includes complex... 
    Senior
    Hourly pay
    Monday to Friday

    Purdue University

    West Lafayette, IN
    3 days ago
  • $112.71k - $169.06k

     ...can all enjoy living in it.Role Summary:As a Cylinder Pack Design Engineer, you will serve as the technical owner for critical engine...  ...development skills - conceptual design, development of products process, data analysis & extraction, failure investigation, and requirements... 
    Senior
    Full time
    Part time
    Relocation
    Relocation package
    Flexible hours

    Caterpillar

    Lafayette, IN
    2 days ago
  • $19.57 - $34.15 per hour

     ...Senior Technician Bridgestone Retail Operations (BSRO) is part of Bridgestone Americas and employs over 22,000 teammates in North America. BSRO operates more than 2,200 company-owned stores, including Firestone Complete Auto Care, Tires Plus and Wheel Works locations... 
    Senior
    Daily paid
    Minimum wage
    Price work
    Full time
    Temporary work
    Part time
    Local area
    Flexible hours

    Bridgestone

    Lafayette, IN
    5 days ago
  • $19.57 - $34.15 per hour

     ...Senior TechnicianBridgestone Retail Operations (BSRO) is part of Bridgestone Americas and employs over 22,000 teammates in North America. BSRO operates more than 2,200 company-owned stores, including Firestone Complete Auto Care, Tires Plus and Wheel Works locations.... 
    Senior
    Daily paid
    Minimum wage
    Price work
    Full time
    Temporary work
    Part time
    Local area
    Flexible hours

    Bridgestone

    Lafayette, IN
    1 day ago
  • $147.76k - $221.64k

     ...providing back-up power to hospitals, providing emergency power when natural disasters strike, and supporting critical infrastructure for data centers, municipalities, and more. With a rich history of more than 95 years in the electric power business, our team has world-... 
    Senior
    Full time
    Part time
    Currently hiring
    Work at office
    Relocation
    Relocation package
    Flexible hours

    Caterpillar

    Lafayette, IN
    1 day ago
  • $21 per hour

    Senior Administrative Assistant City: West Lafayette Job Description: Job Summary At Purdue University, you'll find a collaborative community where people are welcomed, supported, and empowered to make a meaningful impact. The College of Liberal Arts is seeking a Senior... 
    Senior

    Purdue University

    West Lafayette, IN
    3 days ago
  • Scope of Work: The Senior General Superintendent is responsible for overseeing multiple projects and managing various levels of personnel...  ...: Interact with owners, owner representatives, architects, engineers, trade contractors, vendors, and others associated with project... 
    Senior
    For contractors
    Apprenticeship

    Gaylor Electric, Inc.

    Lafayette, IN
    5 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior Data Engineer. Be the first to apply!