Associate Researcher II (Myeloproliferative Neoplasms Research Consortium) - Hematology & Medical Oncology

Description

An Associate Researcher position is available within the Tisch Cancer Center and the Division of Hematology/Medical Oncology at the Icahn School of Medicine at Mount Sinai. The successful candidate will work within a collaborative group of investigators in the Myeloproliferative Neoplasms Research Consortium (MPN-RC) led by Dr. Ronald Hoffman. The laboratory focuses on investigating the stem cell biology of myeloproliferative neoplasms through the use of primary patient samples, induced pluripotent stem cell models, and state-of-the‑art cellular and molecular technologies.

We are seeking a highly motivated, organized, and committed individual who will be responsible for performing laboratory work in support of basic, translational, and clinical research studies. The individual will work closely with laboratory personnel and investigators to conduct experiments, analyze data, and support ongoing research initiatives.

Responsibilities

• Under direct supervision, conducts routine and standardized experiments using research techniques specific to the laboratory's research projects.
• Prepares culture media, reagents, and other materials required for cell culture and laboratory procedures.
• Isolates and processes primary patient samples using density gradient centrifugation, magnetic cell separation, and cryopreservation techniques.
• Performs in vitro cell culture, cell‑based assays, and maintenance of human primary cells and induced pluripotent stem cell cultures.
• Assists with animal studies, including cell preparation, transplantation procedures, post‑transplant monitoring, sample collection, and tissue harvesting from xenografted mice.
• Performs sample preparation, staining, and flow cytometric analyses.
• Conducts basic molecular biology procedures including DNA, RNA, and protein isolation, quantitative PCR, genotyping, and Western blot analysis.
• Maintains accurate and detailed experimental records and laboratory documentation.
• Analyzes and assists in the interpretation of experimental data.
• Assists in the preparation of standard operating procedures, figures, presentations, progress reports, and scientific manuscripts.
• Performs other related duties as assigned.

Qualifications

• Bachelors Degree in sciences or related field or equivalent experience
• 2 years in a research environment or 1 year plus Masters Degree in sciences or related field
• Preferred:
• Experience with human primary cell culture is required; experience with hematopoietic stem cells is strongly preferred
• Experience with induced pluripotent stem cell culture is highly desirable
• Working knowledge of flow cytometry and basic molecular biology techniques, including nucleic acid isolation, PCR, and protein analysis
• Experience with animal research and mouse handling
• Excellent organizational, analytical, and problem‑solving skills
• Strong verbal, written, and interpersonal communication skills
• Ability to maintain detailed experimental records and work effectively in both independent and collaborative research settings
• Demonstrated commitment to scientific research and ability to manage multiple projects in a fast‑paced laboratory environment

Employer Description

Strength through Unity and Inclusion

The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai's unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.

At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well‑being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history.

About the Mount Sinai Health System:

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high‑quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients' medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint‑venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report's “Best Children's Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country's best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek's “The World's Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

Equal Opportunity Employer

The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.

Compensation

The Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $66482.07 - $84560 Annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.