Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Regional Sales Director - South Central

$216k - $265k

Madrigal

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH. Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c). Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration.

To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way. In this role, the Regional Sales Director will develop the regional business strategy and hire and lead a team of high-performing Area Business Managers to achieve/exceed business and sales goals. You will work closely with commercial leadership and collaborate with other senior leaders across the organization to develop and execute strategies and initiatives that contribute to the overall performance, culture and success of the organization. The Regional Sales Director will be a working leader with a player/coach mentality.

The successful candidate will participate in field-based activities; including but not limited to shared ownership of high value regional accounts, (e.g., large Endocrinology group practices, etc.) and relationships with local thought leaders. The Regional Sales Director will be adept at understanding analytics, market research and local geographic trends to identify business opportunities and create comprehensive and detailed business plans for execution at launch. It is expected that the RSD will display a high level of collaboration with colleagues/stakeholders to develop materials and customer-focused initiatives targeted for a diverse range of healthcare professionals.

Key Responsibilities

  • Source, recruit and hire a team of Area Business Managers who are responsible for driving sales results while effectively and compliantly promoting company’s product(s) to targeted HCPs and other healthcare professionals.
  • Drive performance of region and lead by example as a working leader, meeting with top regional accounts and HCPs/staff.
  • Work collaboratively and compliantly with cross-functional field facing partners to develop internal and external customer focused initiatives and deliver a positive customer experience and engagement.
  • Review and analyze district performance and market data in order to develop sales strategies to meet or exceed sales objectives.
  • Drive performance while developing individual contributors on teams through an established coaching and development plan.
  • Manage performance issues with parity and a sense of urgency.
  • Ability to create culture that attracts and retains top talent while driving sales results.
  • Lead by example to master and display high level of clinical acumen; accountability for self and team to demonstrate mastery level of clinical knowledge, including assessments.
  • Demonstrate patient centric mindset.
  • Monitor and ensure utilization of sales and marketing tools and other resources provided to educate healthcare professionals on company’s product(s).
  • Establish and cultivate strategic relationships with physicians and other healthcare professionals within designated geography (working leader).
  • Attend all company-sponsored sales and medical meetings as directed by management; attend live conferences and/or programs as necessary as a Madrigal representative.
  • Comply with all legal, regulatory and compliance policies and demonstrate a high level of integrity and professionalism at all times.
  • Spearhead cross-functional collaboration and serve as an advocate for customer engagement model.
  • Other duties as assigned.

Required & Desired Qualifications

  • Bachelor’s degree required.
  • 5+ years of first-line management experience.
  • 12-15+ years of pharmaceutical/biopharmaceutical, medical or related sales experience.
  • Endocrinology experience strongly preferred.
  • Prior launch experience is required.
  • Local experience, track record of success, and access to relevant regional thought leaders within assigned region strongly preferred.
  • Ability to utilize performance and market data to create actionable business plans to drive sales results.
  • Demonstrated track record of leading successful sales leaders and teams in an environment requiring a high level of initiative, accountability and ethical and compliant actions.
  • Ability to learn complex scientific and technical information and effectively communicate to a broad audience of healthcare professionals.
  • Strong communication skills, including proven ability to successfully influence in the virtual setting.
  • Collaborative, working leader mindset.
  • Proficiency with Microsoft Office Suite.
  • A valid driver’s license and ability to travel as needed (including overnights and/or weekends) is required.
  • Overnight travel up to 50-65%% is expected, depending on regional boundaries.
  • Frequent travel between meeting sites, requiring the ability to sit for extended periods of time.
  • Frequent use of a computer, telephone, printer or other office equipment.
  • Ability to lift up to 20 pounds.

#LI-Remote

Compensation and Benefits

Base salary range for this position is $216,000 - $265,000 per year.

  • All employees receive equity, which we believe reinforces our ownership culture.
  • Flexible paid time off
  • Medical insurance
  • Dental insurance
  • Vision insurance
  • Life/disability insurance
  • 401(k) offerings (i.e., traditional, Roth, and employer match)
  • Supplemental life insurance
  • Legal services
  • Other offerings
  • Mental health benefits through our Employee Assistance Program for employees and their family.
  • Other benefits in accordance with applicable federal, state, and local laws.

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law.

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact View email address on click.appcast.io.

#J-18808-Ljbffr

Vacancy posted 4 days ago
Similar jobs that could be interesting for youBased on the Regional Sales Director - South Central in Mckinney, TX vacancy
  •  ...Madrigal is seeking a Regional Sales Director to lead a high-performing Area Business Manager team across assigned regions. You will develop regional strategies, recruit and mentor field leaders, and drive top-line growth while ensuring compliant promotion of Madrigal’... 
    Suggested

    Jobleads-US

    Mckinney, TX
    4 days ago
  • Green Doorstep in Plano, TX is seeking a Regional Director of Sales to drive revenue growth across Texas and the South. You will lead and expand our B2B sales efforts, nurture key client relationships, and develop tailored solutions for multifamily properties. This strategic... 
    Suggested

    Green Door

    Plano, TX
    4 days ago
  • $56k - $85k

     ...and professionalism - Cash management responsibilities - daily sales/deposit accuracy, regular cash bank deposits, discount...  ...dynamic stylist team in a thriving salon environment, apply now! Location Information: 3190 S. Central Expressway McKinney, TX 75070
    Suggested

    Sportsclips

    Mckinney, TX
    3 days ago
  •  ...product exposure and brand awareness. Responsibilities include developing plans for local chain stores, online retailers, and other channels; planning holiday activities; and delivering regional market insights to support sales growth. #J-18808-Ljbffr ACMEFOG COMMERCE INC
    Suggested
    Local area

    ACMEFOG COMMERCE INC

    Mckinney, TX
    1 day ago
  • Job ID: BSWHUS26019123EXTERNALENUSRequisition: 26019123Company: Baylor Scott & White HealthLocation: Mckinney, Texas, United StatesEmployment type: Full TimeCategory: Shared ServicesIndustry: HealthcareLevel: ManagerShift: Day JobPosted: 2026-10-14About UsHere at Baylor...
    Suggested
    Immediate start

    Baylor Scott & White Health

    Mckinney, TX
    2 days ago
  •  ...including master product scheduling and shop floor scheduling. Provide material availability to support on time deliveries of customer sales orders to meet plant goals. Incorporate final assembly scheduling, work order management, and KANBAN within the CA-KBM software... 
    Work at office
    Immediate start

    Hendrickson

    Mckinney, TX
    1 day ago
  • $250k

     ...immediately. The Role Origina is looking for an experienced Enterprise Sales Executive to take ownership of our Southeast market and play a key role in accelerating our growth across the region. This is a senior, hands-on individual contributor role for someone... 
    Work at office
    Immediate start

    Origina

    Plano, TX
    1 day ago
  •  ...Location: Medical Center-Prosper Department: Central Supply Shift: First Shift (United States of America) Standard Weekly Hours: 40 Summary: The Supply Chain Manager directs the daily logistics and distribution activities. This position provides... 
    Monday to Friday
    Shift work
    Day shift

    Cook Children's Health Care System

    Prosper, TX
    17 hours ago
  •  ...price execution across business units, sales channels, and customer experiences. The...  ...serve as Pricing Application Technology Director. This role is accountable for the strategy...  ...executable delivery plans. You will lead a centralized Pricing Technology team spanning... 
    Bi-weekly pay
    Weekly pay
    Temporary work
    Work experience placement
    Work at office
    Local area
    Remote work
    Flexible hours

    SRS Distribution Inc.

    Mckinney, TX
    1 day ago
  • $86.8k - $165.2k

    Job ID: 01868150Posted: Posted 30+ Days AgoStart Date: 2026-08-26Location: US-TX-RICHARDSON-C17 ~ 1717 Cityline Dr ~ CITYLINE C17; US-MA-ANDOVER-AN0 ~ 366 Lowell St ~ BLDG AN0; US-AZ-TUCSON-940 ~ 1151 E Hermans Rd ~ 940; US-CT-FARMINGTON-0001 ~ 1 Farm Springs Rd ~ 1 FARM...
    Contract work
    Temporary work
    Work experience placement
    Work at office
    Remote work
    Flexible hours
    Shift work

    Raytheon

    Mckinney, TX
    6 days ago
  •  ...The Home Depot family, seeks a Pricing Application Technology Director to lead enterprise pricing technology strategy and execution....  ...architecture across pricing, CPQ, and revenue management. Lead a centralized Pricing Technology team, collaborate with Digital Commerce,... 

    SRS Building Products

    Mckinney, TX
    2 days ago
  • $60k - $90k

     ...Funeral Director Opportunity Gpac is partnering with a respected funeral home to find an experienced, licensed Funeral Director. You'll guide families through arrangements with compassion and also handle preparation and care behind the scenes. What You'll Need:... 

    gpac

    Mckinney, TX
    3 days ago
  •  ...hotels; Provide communication, training and education to GMs and Sales staff to raise their awareness, understanding, and motivation...  ...from third party internet companies, online travel agencies and central reservation offices. Develop and maintain electronic distribution... 
    Seasonal work
    Shift work

    Aimbridge Hospitality

    Plano, TX
    3 days ago
  •  ...Overview The Director, Strategic Procurement & Integration is a senior leadership role responsible for defining and executing Quarterhill...  ..., supplier innovation, and risk mitigation through a centralized and scalable procurement framework. Working closely with executive... 
    Contract work

    UNAVAILABLE

    Frisco, TX
    1 day ago
  •  ...the branch location, engaging customers and team members to drive sales and increase deposits. This position offers a dynamic...  ...Maryland, Mississippi, New York, North Carolina, Ohio, Pennsylvania, South Carolina, Texas, Virginia and West Virginia. #J-18808-Ljbffr
    Full time
    Temporary work
    Bank staff
    Local area
    Flexible hours

    Woodforest National Bank

    Mckinney, TX
    3 days ago
  • $50k - $250k

     ...growing roofing contractor serving homeowners across Texas, Atlanta, South Carolina, and North Carolina . The company specializes in roof...  ...is committed to protecting what matters most—your home. Sales Representative (Door-to-Door) Position Overview: Results Roofing... 
    For contractors
    Flexible hours

    Results Roofing LLC

    Mckinney, TX
    more than 2 months ago
  • 6094 - McKinney - 1441 N Central Expy, McKinney, Texas, 75070 CarMax, the way your career should be! Driven by the desire to provide an...  ...they want in a way that suits them. That demands a special kind of sales consultant: one who takes time to build relationships with... 

    CarMax

    Mckinney, TX
    2 days ago
  • $132.4k - $251.6k

    Job ID: 01877736Posted: Posted 10 Days AgoStart Date: 2026-10-06Location: US-TX-MCKINNEY-513WA ~ 2501 W University Dr ~ WING A BLDGCountry: United States of AmericaTime Type: Full timeDate Posted:2026-10-06 Country:United States of America Location:US-TX-MCKINNEY-513WA...
    Temporary work
    Work experience placement
    Interim role
    Work at office
    Local area
    Remote work
    Relocation
    Flexible hours

    Raytheon

    Mckinney, TX
    4 days ago
  •  ...salon quality products at a value price. Beauty Systems Group, branded as Cosmo Prof or Armstrong McCall stores, along with its direct sales consultants, sell professionally branded products intended for use and resale by salons to retail consumers. About the role... 
    Contract work
    Work at office

    CosmoProf

    Plano, TX
    4 days ago
  •  ...Policies and Procedures which align with SBH corporate goals, and allow for effective procurement of all required Private Label good for sale, in accordance with industry best practices. This will include assisting in the procurement of Private Label product for... 
    Contract work
    Work at office

    Sally Beauty

    Plano, TX
    13 hours ago
  •  ...that balance cost, service, capacity, and risk to support competitive pricing and effective sourcing decisions.Working closely with Sales, Operations, Finance, Legal, and transportation providers, the Manager independently leads assigned pricing and sourcing workstreams... 
    Full time
    Contract work
    Temporary work
    Flexible hours

    SAMSUNG SDS

    Plano, TX
    3 days ago
  •  ...with strong operational support. You will lead discovery and backlog management, measure success with key metrics, and mentor teams focused on invoicing and procurement while integrating tools like Ariba, Concur, and Supplier Central. #J-18808-Ljbffr JPMorgan Chase & Co.

    JPMorgan Chase & Co.

    Plano, TX
    4 days ago
  • $150k

    Overview: Looking for a full-time sales opportunity with unlimited earning potential? We are hiring immediately for Sales Consultants...  ...by Andersen of Nevada, Arizona, Colorado, Oklahoma, North Texas, Central Texas, Greater Philadelphia, Southern New England and Portland,... 
    Full time
    Immediate start
    Flexible hours
    Weekend work
    Afternoon shift

    Renewal by Andersen | Esler Companies

    Mckinney, TX
    13 hours ago
  • $174k - $261k

     ...inspires a brighter work day for all. The Enterprise Management Sales team at Workday helps the company to continue to grow by...  ...environment with an amazing team of people. About the Role As a Regional Sales Director you will use your extensive sales and leadership experience... 
    Work at office
    Local area
    Remote work
    Home office
    Flexible hours

    Workday, Inc.

    Frisco, TX
    4 days ago
  •  ...experienced International Logistics & Supply Chain Director to lead global inbound logistics...  ...leader will also partner closely with sales, finance, and operations to strengthen service...  ...such as Microsoft Dynamics 365 Business Central and Power BI. • Proven ability to... 
    Overseas

    Robert Half

    Plano, TX
    7 days ago
  • Join Asset & Wealth Management (AWM) Finance to lead the delivery and evolution of quantitative forecasting tools that power stress testing and business-as-usual exercises. You’ll shape end-to-end Python-based tooling and GenAI-enabled applications, lead a talented team...

    JPMorgan Chase & Co.

    Plano, TX
    3 days ago
  • $174k - $261k

    Large Enterprise Customer Base Regional Sales Director - Healthcare Location: USA, TX, Frisco, USA, GA, Atlanta Remote Type: Flex Time Type: Full Time Job Description Your work days are brighter here. We’re obsessed with making hard work pay off, for our people, our customers... 
    Full time
    Work at office
    Remote work
    Home office
    Flexible hours

    Workday

    Frisco, TX
    1 day ago
  • We are looking for a Supply Chain Manager to oversee purchasing, supplier strategy, inventory planning, and logistics operations in Texas. This role plays a key part in maintaining material availability, controlling costs, and supporting production and program schedules...
    Contract work

    Robert Half

    Mckinney, TX
    3 days ago
  • $75 per hour

    Job Title: eCommerce Marketing Manager Location: Plano, TX Pay Rate: $75.00/hr. Schedule: Fully on-site, Monday - Friday | 8:00 AM to 5:00 PM (hours may vary) Staffmark Total Talent Solutions offers this exciting contract opportunity...
    Contract work
    Work at office
    Local area
    Monday to Friday

    Staffmark

    Plano, TX
    2 days ago
  •  ...execute data-driven advertising strategies that drive profitable sales growth. Manage advertising budgets, bidding strategies, campaign...  ...marketing and advertising claims. Experience with Amazon Seller Central, Amazon Brand Analytics, and Walmart Seller Center. Knowledge of... 
    Full time
    Fixed term contract
    Seasonal work
    Work at office
    Relocation
    Monday to Friday

    Herbal Goodness

    Mckinney, TX
    13 hours ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Regional Sales Director - South Central. Be the first to apply!