Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Associate Director, RDU IT - Business Partner, US Commercial

$124.32k - $163.17k

WHY JOIN US?

At Alexion, a division of AstraZeneca, we are driven by a shared purpose to transform the lives of people affected by rare and devastating diseases. By combining deep expertise in rare disease with the scale, science, and innovation of AstraZeneca, we are working to deliver meaningful advances for patients and families with significant unmet needs. 

Join us at an exciting time as we continue to evolve how technology, data, digital capabilities, and AI support our Commercial organization. You will have the opportunity to work closely with business and technology leaders, shape solutions that enable new product launches and commercial transformation, and help turn emerging technologies into measurable outcomes for patients and the business. 

Our culture is built on collaboration, innovation, and continuous learning. We encourage our people to challenge convention, explore new possibilities, and bring forward ideas that can improve how we work and how we serve patients. As part of Alexion, you will have the opportunity to make an impact in a highly specialized area of healthcare while benefiting from the capabilities and global reach of AstraZeneca. 

Hybrid Policy We also recognize the importance of flexibility and balance. Our ways of working support both individual needs and meaningful in-person collaboration. This role is based in Boston, MA, with employees expected to work from the office three days per week , creating opportunities for teams to connect, collaborate, and solve complex challenges together.

Introduction

At Alexion, a division of AstraZeneca, we are dedicated to transforming the lives of patients impacted by rare and devastating diseases. As Director, RDU IT Business Partner, US Commercial, you will serve as a senior business-facing technology partner, shaping and delivering technology, data, digital, and AI-enabled capabilities that support commercial priorities, launch readiness, commercial transformation, and improved patient outcomes.

This position is based in Boston, MA, and may require up to 20% travel.

Position Summary

The Associate Director, RDU IT Business Partner, US Commercial will serve as an IT Business Partner for the US Commercial organization, with a defined portfolio spanning Commercial business functions, Commercial Training, Rare Disease Therapy Area teams, launch, Commercial Operations, Strategic Accounts & Diagnostics and enabling functions and AI-enabled transformation.

This role will build trusted relationships with senior Commercial stakeholders, shape the multi-year technology and AI roadmap for assigned business areas, lead demand prioritization, steward portfolio health, and partner across IT, Digital, Data, AI, Architecture, Cybersecurity, Privacy, Compliance, Finance, Service Delivery, and external partners to deliver measurable business outcomes.

Key Responsibilities

  • Serve as an IT Business Partner and trusted advisor for assigned US Commercial business areas, aligning technology, data, digital, and AI roadmaps to business priorities.
  • Build and maintain trusted relationships with senior stakeholders across US Commercial, Commercial Training, Rare Disease Therapy Area teams, launch, REMS, Commercial Operations, Strategic Accounts & Diagnostics, and enabling functions.
  • Partner with business leaders to translate strategic objectives into capability roadmaps, prioritized demand, investment options, and measurable outcomes.
  • Steward assigned Commercial IT portfolio activities, including demand intake, prioritization, funding alignment, risks, dependencies, value realization, ServiceNow visibility, and executive reporting.
  • Lead disciplined business capability mapping and technology roadmap development, ensuring roadmaps reflect business strategy, process maturity, data readiness, AI opportunity, and adoption needs.
  • Support Market Access and Business Unit priorities at the portfolio level by translating key business needs into scalable, compliant technology and data-enabled solutions.
  • Ensure assigned commercial solutions include appropriate governance, compliance, privacy, financial controls, adoption planning, and measurable value outcomes.
  • Lead launch technology planning for new products, indications, and therapy area priorities with Sales, Marketing, Commercial Training, Market Access, and business operations.
  • Lead through influence across business, IT, data, AI, architecture, delivery, and vendor teams; coach colleagues on business partnering, AI literacy, portfolio governance, executive communication, and value realization.

AI-Ready Business Partner Responsibilities

  • Enable AI for the business by identifying, framing, prioritizing, and scaling high-value AI, GenAI, agentic AI, automation, analytics, and data product opportunities across US Commercial workflows.
  • Translate AI ideas into business-ready use cases with clear problem statements, target users, data requirements, operating model impacts, success measures, risks, and adoption requirements.
  • Drive AI-enabled business outcomes across commercial decision support, launch readiness, Commercial Training enablement, executive reporting, forecasting support, customer engagement, and portfolio prioritization.
  • Champion responsible AI adoption by partnering with Data, AI, Architecture, Cybersecurity, Privacy, Legal, Compliance, and business stakeholders to define explainability, traceability, human oversight, auditability, security, and value measurement requirements.
  • Move the business from AI experimentation to measurable business impact by defining baselines, success metrics, adoption targets, governance requirements, and continuous improvement loops.
  • Model AI-enabled business partnering by using approved AI tools and LLM-enabled workflows to improve stakeholder preparation, meeting synthesis, portfolio reporting, roadmap development, risk identification, executive communication, and follow-through.
  • Use AI-assisted analysis to improve demand intake, synthesize stakeholder feedback, compare requirements, identify duplicate or overlapping requests, and generate clearer business problem statements.
  • Apply AI to organize knowledge, transition documentation, initiative history, open risks, dependencies, decisions, and stakeholder context while validating outputs and protecting sensitive information. 
  • Coach business and IT partners with practical, compliant AI usage patterns that improve productivity, quality, decision speed, and accountability.

Essential Qualifications

  • Bachelor's degree in computer science, MIS, Business, Life Sciences, Data / Analytics, or related fields.
  • 12+ years of experience in IT, digital, data, commercial technology, or enterprise technology roles, including business partnership, portfolio ownership, solution delivery, and cross-functional leadership.
  • Experience working in biotech, pharmaceutical, medical device, life sciences, or another regulated industry.
  • Demonstrated experience as a senior IT Business Partner or technology leader supporting Commercial, Sales, Marketing, Market Access, Patient Services, Commercial Operations, Finance, or related business functions.
  • Strong understanding of US Commercial business processes, launch planning, sales and marketing operations, commercial operations, portfolio governance, and value realization.
  • Working knowledge of Market Access, commercial operations, Master Data Management, and related financial decision-support processes.
  • Experience shaping or delivering data, analytics, digital, automation, AI, or technology-enabled transformation capabilities.
  • Experience with CRM and related commercial platforms such as Salesforce, Veeva, or other life sciences commercial technologies.
  • Strong understanding of data products, analytics, reporting, commercial data foundations, SDLC, Agile practices, privacy, security, quality, compliance, and regulatory expectations.
  • Experience managing portfolio funding, business cases, risks, dependencies, vendor engagement, and executive-level reporting.
  • Ability to influence senior stakeholders, simplify complexity, drive alignment, communicate technology concepts in business language, and connect technology investments to business value, patient impact, efficiency, adoption, and risk reduction.

Preferred Qualifications

  • Master’s degree preferred.
  • Experience supporting Commercial, Finance, Patient Services, Launch Excellence, Commercial Training, CRM, or Rare Disease Therapy Area technology portfolios.
  • Experience with Salesforce Health Cloud, Salesforce Life Sciences Cloud, Veeva, Service Cloud, Experience Cloud, ServiceNow, Snowflake, data products, BI / analytics platforms, or AI-enabled commercial platforms.
  • Experience with rare disease commercial models, specialty pharmacy, patient access, payer engagement, field reimbursement, care coordination, or high-touch business-facing environments.
  • Experience leading governance forums, executive portfolio reviews, vendor partnerships, product-oriented operating models, transformation programs, adoption plans, and value-realization plans.
  • Familiarity with responsible AI principles, including explainability, traceability, human oversight, auditability, privacy, compliance, risk management, and adoption of governance.
  • Strong leadership presence with the ability to balance strategic thinking, operational discipline, stakeholder empathy, and execution focus.

SO, WHAT’S NEXT?

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.

Where can I find out more?

  • Explore what we’re building:
  • Stay connected and see our impact in action:

Apply today to shape the future of AI-powered rare disease care! Alexion is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. Alexion is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing View email address on us.fitly.work .

#LI-Hybrid The annual base pay for this position ranges from $124,320.00 - $163,170.00 USD. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. 

In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans.

Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. 

Date Posted

11-Nov-2026

Closing Date

24-Nov-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the Associate Director, RDU IT - Business Partner, US Commercial in Boston, MA vacancy
  • $153.02k - $229.53k

    Role OverviewAs Director, IT Business Partner - Global Medical Affairs, you will serve...  ...in the Rare Disease Unit (RDU). In this strategic role,...  ...functional initiatives with Commercial, R&D, and enabling functions...  ...form.SummaryLocation: US - Boston - MAType: Full time
    Commercial
    Full time
    Temporary work

    Alexion Pharmaceuticals

    Boston, MA
    4 days ago
  • $195k - $225k

     ...alter the course of lives.The IT Business Relationship Director is the senior technology...  .... Salesforce is the key commercial platform for both Epilepsy...  ...the role. The Director will partner closely with the...  ...address.SummaryLocation: US_Remote; Chicago, Illinois,... 
    Commercial
    Full time
    Part time
    Local area
    Remote work
    Worldwide

    LivaNova

    Boston, MA
    14 hours ago
  • $180k - $200k

     ...Description Job Description The Associate Director, Commercial Technical Solutions serves as a key bridge between Business Development, Technical...  ...& Technical Solutions Partner with Business Development and...  ...information about how your data is processed, please contact us.... 
    Commercial

    Artis BioSolutions

    Watertown, MA
    5 days ago
  • $183k - $252k

     ...About this role The Associate Medical Director, Rare Disease role is...  ...Affairs, a strategic partner within Biogen, that...  ...a key member of the US Rare Disease Medical...  ..., Pharmacovigilance, Commercial, Market Access). Collaborate...  ...Understand the local business needs and provide... 
    Commercial
    Full time
    Temporary work
    Work at office
    Local area

    Biogen

    Cambridge, MA
    3 days ago
  • $128.94k - $193.41k

     ...Alexion-Rare Disease Unit (RDU) IT. As the Associate Director of RDU IT Communications and Change...  ...for RDU IT, aligned with business priorities. Manage...  ...diverse media channels. Partner with process owners and leaders...  ...In-person working gives us the platform we need to... 
    Suggested
    Hourly pay
    Full time
    Contract work
    Temporary work
    Work at office
    Flexible hours
    Shift work
    3 days per week

    AstraZeneca

    Boston, MA
    10 hours ago
  • $164k - $225.5k

    About This Role:As the Associate Director of Data Science & AI,...  ...making across our U.S. Commercial organization....  ...commercial effectiveness.Partner with Commercial, Medical...  ...insights into evidence-based business strategies.Communicate...  ...and perspectives make us a stronger and more... 
    Commercial
    Full time
    Temporary work
    Local area
    3 days per week

    Biogen Idec

    Somerville, MA
    1 day ago
  • $183k - $252k

    About this roleThe Associate Medical Director, Rare Disease role is a...  ...Affairs, a strategic partner within Biogen, that helps...  ...a key member of the US Rare Disease Medical...  ..., Pharmacovigilance, Commercial, Market Access)....  ...Understand the local business needs and provide insights... 
    Commercial
    Full time
    Temporary work
    Work at office
    Local area

    Biogen Idec

    Somerville, MA
    1 day ago
  • $154.4k - $242.55k

     ...and be empowered to deliver your best. The US Oncology Market Access Analytics Lead...  ...actionable insights, and communicate the business impact to cross-functional stakeholders to...  ...market access space.How you will contribute:Partner with various US OBU PVA functions to... 
    Minimum wage
    Local area
    Remote work

    Takeda

    Boston, MA
    1 day ago
  • $184k - $218k

    Associate Director, IT Application Management (Market Access & Patient...  ...is an independent, commercial-stage...  ...governed model gives us the freedom to invest...  ...technology lead and strategic partner for the Market Access...  ...intelligence. Working across business, enterprise IT, data... 
    Commercial
    Contract work
    Temporary work
    Flexible hours

    Les Laboratoires Servier

    Boston, MA
    1 day ago
  • $154.4k - $242.55k

     ...DescriptionAbout the role:The Associate Director, Global and US Pipeline Forecasting Lead...  ...in the Oncology Business Unit (OBU) and is responsible...  ...leadership to cross-functional partners (e.g., Finance, Supply,...  ...the potential impact of commercial strategies are planned... 
    Commercial
    Minimum wage
    Local area
    Remote work

    Takeda

    Boston, MA
    1 day ago
  • $10k

    About This RoleThe Associate Director of Strategy and Operations...  ...role in ensuring the US Market Access & Reimbursement...  ...on its strategy and business priorities by driving...  .... This role will partner closely with cross-functional...  ...leaders across Commercial, Franchises, Medical,... 
    Commercial
    Full time
    Temporary work
    Local area

    Biogen Idec

    Cambridge, MA
    2 days ago
  • $177.6k - $266.4k

     ...science, technology, and business to address complex challenges...  ...an exciting phase of commercial diversification. As we expand...  ..., External Affairs, and partner functions.The Associate Director, AI UX Design is...  ...External Affairs across US and International markets... 
    Commercial
    Full time
    Summer work
    Remote work
    Flexible hours
    Shift work
    2 days per week

    Vertex Pharmaceuticals

    Boston, MA
    1 day ago
  • $162k - $184.5k

     ...work benefits clients and partners as much as it does its...  ...Technology company, supports commercial and SMB markets in the U....  ...is to bring together business acumen with full-stack technical...  ...Technology is hiring an Associate Client Solutions Director (ACSD) to lead delivery... 
    Commercial
    Full time
    Contract work
    Shift work

    World Wide Technology

    Cambridge, MA
    1 day ago
  •  ...to be the reinvention partner of choice for our clients...  ...stakeholders. Visit us at accenture.com....  ...transformation initiatives to business outcomes including...  ...Strong consulting and commercial acumen, including experience...  ...work experience. (If Associate’s Degree, must have... 
    Commercial
    Work experience placement
    Live in
    Work at office
    Local area

    Accenture

    Boston, MA
    2 days ago
  • $151.08k - $226.62k

     ...This is what you will do: The Associate Director, US HCP Peer-to-Peer (P2P) Marketing,...  ...Rare Neurology, is a member of the commercial U.S. Rare Neurology business unit and reports to the Sr....  ...competitive rare neurology markets, partnering closely with the gMG and NMOSD... 
    Commercial
    Temporary work
    Work at office
    Night shift
    Boston, MA
    more than 2 months ago
  •  ...Description Job Description Associate Director (Data Integration & Commercial Analytics) Duration: 9–12 months...  ...looking for someone to serve as a core Business Analyst (AD level) who can...  ...and cross‑functional alignment. Partner with technical teams on data mapping... 
    Commercial

    KMK Consulting, Inc.

    Boston, MA
    6 days ago
  • $183k - $200k

     ...delivering and evolving technology solutions across Commercial and Medical. Reporting to the Director, IT Commercial Business Partner, you’ll partner across Commercial, Medical...  ...83,000—$200,000 USD To stay connected with us, follow Amylyx Pharmaceuticals on LinkedIn .... 
    Commercial
    Local area
    Remote work
    1 day per week

    Amylyx Pharmaceuticals

    Cambridge, MA
    9 hours ago
  • $132.5k - $271k

     ...be the reinvention partner of choice for our...  ...25 revenue. Visit us at accenture.com.WHO...  ...Senior Manager / Associate Director, you will play a...  ...workstreamsTranslate client business and engineering...  ..., software, IT, and digital leaders...  ...dependencies, and commercial guardrails across... 
    Commercial
    Live in
    Work at office
    Local area

    Accenture

    Boston, MA
    2 days ago
  •  ...including: disease model development, AAV discovery, drug efficacy studies, and more. Position Description We are seeking 2 US BD Managers to lead our commercial expansion in the United States. This role involves technical sales, market development, and customer relationship... 
    Commercial

    Cyagen US Inc.

    Boston, MA
    1 day ago
  •  ...building an integrated commercial technology, data,...  ...services, analytics, and business growth.The Associate Director, Commercial...  ...Associate Director partners closely with Commercial...  ...the interface to the IT vertical Leader for...  ...thinking, allowing us to bring groundbreaking... 
    Commercial
    3 days per week

    Alnylam Pharmaceuticals

    Somerville, MA
    4 days ago
  • $160k - $240k

     ...Operational Excellence & Business Analytics team serves as...  ...Vertex's external commercial manufacturing network.The Associate Director, Operational Excellence...  ...functional leadership. The role partners closely with Network...  ...partnering with digital/IT functions on data pipelines... 
    Commercial
    Full time
    Summer work
    Remote work
    Flexible hours
    2 days per week

    Vertex Pharmaceuticals

    Boston, MA
    1 day ago
  • $235k - $260k

     ...health and transform lives. Join us on our journey of growth! Summary: The Associate Director, Legal Affairs serves as a strategic, solution-oriented business partner, building strong stakeholder...  ...across a broad range of commercial, technology, and healthcare matters... 
    Commercial
    Contract work
    Private practice
    Flexible hours

    Lundbeck

    Boston, MA
    16 days ago
  • $164k - $194k

     ...Boston Country/Region: US Type of Contract:...  ...ID: 12320 Associate Director, Biostatistics About...  .... is a Boston-based, commercial-stage biopharmaceutical...  ...activities. This role partners closely with clinical...  ...ability to evaluate business impact, follow through... 
    Commercial
    Full time
    Contract work
    Temporary work
    Remote work
    Flexible hours

    Servier Pharmaceuticals

    Boston, MA
    14 hours ago
  • $160k - $240k

     ...Rhythm is a global, commercial-stage biopharmaceutical...  ...courage inspires us to challenge convention...  ...Rhythm is seeking an Associate Director, Biostatistics to join...  ...program activities, partnering across clinical, regulatory...  ...their department and business needs. This role may... 
    Commercial
    Interim role
    Work at office

    Rhythm Pharmaceuticals

    Boston, MA
    3 days ago
  •  ...Job title: Associate Director of Respiratory Provider Experience...  ...Director of US Respiratory Provider...  ...contributors and alliance partners, and orchestrates their...  ...experience in HCP marketing, commercial operations, or field...  ...or masters degree in business, marketing, or health... 
    Commercial
    Work at office

    BioSpace, Inc.

    Cambridge, MA
    3 days ago
  • $180k - $250k

     ...Title: Associate Director, Medical Affairs Company: Ipsen Biopharmaceuticals...  ...the company’s success. Join us on our journey towards...  ...our teams. The role will also partner closely with the US and Global...  ...Medical Affairs subfunctions, Commercial teams, and Global Medical... 
    Commercial
    Temporary work
    Local area
    Flexible hours

    IPSEN

    Cambridge, MA
    1 day ago
  • $218.12k - $264.31k

     ...Associate Director, Biostatistics Working with Us Challenging. Meaningful. Life-changing. Those...  ...clinical, regulatory and commercial environments with...  ...scientific and strategic partner in the drug development...  ...supplemental health insurance, business travel protection,... 
    Commercial
    Hourly pay
    Full time
    Temporary work
    Part time
    For contractors
    Summer work
    Work at office
    Remote work
    Flexible hours
    Shift work

    Bristol-Myers Squibb

    Somerville, MA
    14 hours ago
  • $190k - $206k

     ...a highly motivated Associate Director, Data Architecture to...  ...platform as we prepare for commercial growth and future...  ...and will partner closely with business stakeholders, external...  ...Partner with business and IT leaders to establish...  ...stay connected with us, follow Amylyx... 
    Commercial
    Local area
    Remote work

    Amylyx Pharmaceuticals

    Cambridge, MA
    9 hours ago
  • $250k

     ...deep experience in commercial real estate, skilled...  ...This Job InvolvesThe Associate Program Director for the Americas serves...  ...and First Day of Business to protect operational...  ...workflowsExperience partnering with general...  ...information provided to us seriously. Generally... 
    Commercial
    Full time
    Contract work
    For contractors
    Work at office
    Local area
    Remote work

    Jones Lang LaSalle

    Boston, MA
    21 hours ago
  • $168k - $252k

     ...) Operations and Analytics Associate Director leads sophisticated analyses...  ...that inform and drive key business decisions— supporting both...  ...questions and inform access and commercial decisionsPlay a key role in the forecasting process, partnering with the GTN team to... 
    Commercial
    Full time
    Temporary work
    Summer work
    Remote work
    Flexible hours
    2 days per week

    Vertex Pharmaceuticals

    Boston, MA
    1 day ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Associate Director, RDU IT - Business Partner, US Commercial. Be the first to apply!