Senior Software Engineer

Senior Software Engineer - Brooklyn, NY | full-time

$150,000 - $225,000 base, plus equity. Based on experience.

The Role

Caladan Bio is looking for a Senior Software Engineer to help architect and design the digital platform behind our advanced bioreactor systems. We are open to full-stack leaning towards the frontend or the backend. You will help build the core services and infrastructure needed to run our hardware, automation, and machine learning platforms. You will be responsible for architecting systems that control and orchestrate a fleet of modular lab instruments capable of generating and analyzing high density streams of fermentation data from hundreds of actuators and sensors. We are looking for someone with experience collaborating across a complex stack of hardware, firmware, and software to deliver reliable and efficient software for our customers.

Caladan Bio is automating the process of bringing synthetic biology products to market. We're building the infrastructure (automated hardware, software, and AI) to power the future of biomanufacturing - starting on the benchtop in the earliest stages of R&D and partnering with companies through scale-up. Our flagship product, the Caladan 250, is a high performance benchtop bioreactor system that is enabling our customers to run double the number of experiments.

At Caladan we believe that the future of biomanufacturing will be driven by advancements that span the entire tech stack from genomics all the way through AI and robotics. The dynamic of the problem set we are tackling presents unique challenges, but also opportunities for outsized impact on an industry that will bring the most important technological advancements to our society over the next 100 years.

Caladan Bio is building the next generation of biomanufacturing technology. Our mission is to help industrial biology and biopharma companies bring bio-based products to market faster. The Caladan 250 is a high-throughput benchtop bioreactor platform designed to increase experimental capacity while making bioprocess development more accessible, flexible, and efficient.

Caladan is based in Brooklyn, NY, and is backed by Twelve Below, Lerer Hippeau, Collaborative Fund, and Wireframe Ventures.

What You’ll Do

• Collaborate with stakeholders on the hardware, lab, and commercial teams to shape our users' experience within the Caladan platform.
• Build and maintain the software that underpins the entire Caladan ecosystem of hardware.
• Integrate real-time data from bioreactors into full-featured visualization and analysis tools.
• Develop a foundation for Caladan’s data and machine learning systems.
• Design scalable APIs and data pipelines for experiment tracking, device management, and user interaction.
• Write tests, monitor performance, and improve system reliability in production.
• Troubleshoot problems quickly and communicate effectively about solutions.
• Contribute to overall system architecture and help define best practices for software development.

What You’ll Bring

• 5+ years of experience building and shipping software in production environments.
• Expert-level skills using Python or React+Typescript
• Strong fundamentals in software architecture, distributed systems, and debugging.
• Sense of ownership of the whole product lifecycle.
• A hands-on, collaborative mindset and interest in building with physical systems.
• Ability to work onsite in our Brooklyn, NY headquarters.

Nice to Have, but Not Required

• Experience in biotech, lab automation, or scientific instrumentation.
• Exposure to IoT or edge-device communication frameworks.
• Experience shipping software for hardware products.
• Knowledge of firmware level languages and architectures

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