In Vivo Research Associate, Oncology

In vivo Research Associate, Oncology We build DNA computers that run molecular programs in cells to treat cancer and other diseases. Using multi‑input molecular‑level computation in individual cells, our approach leads to curative therapies where the conventional one drug‑one target paradigm has failed to deliver effective treatments. We are building a world‑class team at our headquarters in South San Francisco to translate two decades of scientific progress in DNA computing and synthetic biology into the clinic. About the role You will perform in vivo studies of our AAV‑based cancer therapeutic candidates to advance our oncology pipeline and technology platform. You will contribute to the design of the preclinical studies and their execution, ensuring a high level of scientific rigor and compliance with relevant regulations. This is an ideal position for a candidate with a strong background in vivo experiments who thrives in a team‑oriented, cross‑disciplinary, and collaborative environment. Key responsibilities Plan and execute in vivo studies in collaboration with discovery and data scientists Perform various in vivo procedures in mice: dosing via IV, IP and SC, blood sampling, and complex surgeries to establish orthotopic tumor models via abdominal surgery Conduct routine animal health monitoring and recording and monitor tumor volume by in vivo imaging or caliper measurement Perform necropsy, biological sample processing (e.g. FFPE and OCT), tissue dissociation and cell sorting via MACS or FACS, and downstream analysis such as flow cytometry and immune assays Conduct mammalian cell culture and QC for in vivo experiments Generate, document and analyze in vivo study data in accordance with study protocols, SOPs, and regulatory guidelines Interface with external laboratories and partners Who you are MSc in life sciences At least 3 years of hands‑on experience working with murine oncology models in an academic or industry setting Strong hands‑on experience with complex rodent procedures, such as thoracic or abdominal surgery, suturing and wound closure, and tail vein dosing Experience in necropsy, tissue handling and processing, tumor cell and splenocyte isolation, and flow cytometry Detail‑oriented with strong organizational and record‑keeping skills Excellent communication skills and ability to collaborate effectively in a cross‑functional team Experience working in a GLP or regulatory‑compliant environment is a plus #J-18808-Ljbffr Planet Pharma