Senior Medical Director, Clinical Science ,NS TAU- Sleep Medicine

Job Overview Join us as a Senior Medical Director, Clinical Science Neuroscience, in our Cambridge, MA office. At Takeda, we are transforming the pharmaceutical industry through our R&D‑driven market leadership and being a values‑led company. We empower our people to realize their potential through life‑changing work. As a certified Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence. An inclusive, collaborative workplace unites our global teams in a commitment to deliver Better Health to people worldwide. You will be a vital contributor to our inspiring, bold mission. OBJECTIVES The Medical Director leads and drives strategy for the overall global (US/EU/Japan) clinical development, considering medical, scientific, regulatory and commercial issues for assigned Takeda pipeline compounds. Leads a multi‑disciplinary, multi‑regional matrix team through highly complex decisions, creating and executing a global clinical development plan that leads to regulatory approval across multiple regions. Provides clinical/medical decision making for development issues and influences senior leadership through strategic direction. ACCOUNTABILITIES Clinical Development team participation and leadership: Lead global (US/EU/Japan) Development Team, manage US/EU and Japan teams; represent Clinical Science on the global development team ensuring alignment with strategy; develop strategy, plan and protocols; recommend scope, complexity, size and influence budgets; perform critical evaluation to keep plan state‑of‑the‑art; handle high‑impact global decisions based on data analytics. Synopsis / Protocol Development, Study Execution & Interpretation: Drive preparation and approval of synopses, protocols and conduct of studies; advise other scientists; accountable for design and interpretation of studies; present conclusions to management and assess scientific significance. Trial Medical Monitoring: Medical monitoring of protocol conduct and subject safety; assess safety data with pharmacovigilance; oversee non‑medical scientists; make final scientific integrity decisions. External Interactions: Lead interactions with regulatory authorities, key opinion leaders, set strategies, direct clinicians involved in documents and presentations; incorporate advice into study design; accountable to senior leadership for objectives. Due Diligence, Business Development & Alliance Projects: Identify and evaluate business development opportunities; conduct due diligence; negotiate clinical development plans for alliances; evaluate feasibility and strategic fit; serve as clinical contact for ongoing alliance projects. Leadership, Task Force Participation & Upper Management Accountability: Interact with research division and provide expertise; represent Clinical Science on multidisciplinary task forces; lead internal and global cross‑functional teams; hire, manage, mentor, motivate, develop staff; conduct performance reviews and drive goal setting. TRAVEL REQUIREMENTS Ability to drive or fly to various meetings or client sites, including overnight trips. Approximately 15 – 25% travel; the role is classified as “hybrid” per Takeda’s Hybrid and Remote Work policy. COMPENSATION AND BENEFITS U.S. Base Salary Range: $257,600.00 – $404,800.00 (actual base salary may vary by qualifications, experience, skills, education, certifications, licensure, and location). U.S. employees may be eligible for incentives, medical, dental, vision, 401(k) with match, disability coverage, life insurance, tuition reimbursement, paid volunteer time, company holidays, well‑being benefits, sick time (up to 80 hours annually), and paid vacation (up to 120 hours for new hires). EDUCATION, COMPETENCIES & SKILLS MD or internationally recognized equivalent plus ≥7 years of clinical research experience in the pharmaceutical industry, CRO, health‑related consulting or academia. Previous experience leading a clinical development team/matrix team across multiple regions. NDA/MAA/Submission experience preferred. Management experience. Key competencies: Superior communication, strategic, interpersonal and negotiating skills Proactive problem solving and decision‑making within a multi‑disciplinary, multi‑regional, matrix team Diplomacy and positive influencing abilities Therapeutic area knowledge relevant to mechanism of action; expertise in sleep medicine preferred Regulatory requirements, GCP/ICH, emerging research in designated area EEO STATEMENT Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. LEGAL NOTICE It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. #J-18808-Ljbffr Takeda Pharmaceuticals International GmbH