Senior Director / Clinical Lead (Study Physician) Cardio

Senior Director / Clinical Lead (Study Physician) Cardio Location Princeton, New Jersey area, United States of America Job Type Full-time Description Senior Director / Clinical Lead (Study Physician) Cardio | Biotech | Clinical-Stage Cardiovascular Biotechnology Company Our client is a well-funded, clinical-stage biotechnology company focused on developing innovative therapies for serious cardiovascular diseases with significant unmet medical needs. The organization is advancing novel therapeutic approaches designed to improve outcomes for high-risk patient populations through cutting-edge science and rigorous clinical development. The company combines deep scientific expertise with an entrepreneurial biotech culture where individuals have the opportunity to make a meaningful impact across clinical strategy, development, and execution.

POSITION OVERVIEW:

Our client is seeking an experienced and highly motivated Senior Director / Clinical Lead (Study Physician) to provide clinical leadership for ongoing and planned cardiovascular clinical development programs. This individual will play a critical role in the design, execution, monitoring, and interpretation of clinical trials, with immediate focus on a later-stage cardiovascular program. The successful candidate will serve as a key medical and scientific leader across cross-functional study teams and will work closely with Clinical Operations, Biostatistics, Regulatory, Safety, Translational Medicine, and external investigators. This role is ideal for a hands-on clinical development professional who thrives in a fast-paced biotech environment and enjoys operating at the intersection of strategy, execution, and scientific innovation. Location Princeton, New Jersey area Features WHAT MAKES THIS OPPORTUNITY UNIQUE: Opportunity to help lead development in an underserved and highly impactful cardiovascular disease setting Opportunity to work on a novel therapeutic platform with significant scientific and clinical potential Direct influence on clinical strategy and study execution within a growing biotechnology company Highly collaborative culture with experienced leadership and development teams Opportunity to contribute meaningfully to programs designed to improve outcomes for severely ill cardiovascular patients Responsibilities Serve as the clinical lead and study physician for ongoing and planned cardiovascular clinical trials Provide medical oversight and leadership for study conduct, patient eligibility review, protocol deviations, safety monitoring, and data review Lead development and review of clinical protocols, protocol amendments, investigator brochures, clinical study reports, and related study documents Partner cross-functionally with Clinical Operations, Biostatistics, Data Management, Regulatory Affairs, Pharmacovigilance, and Translational teams to drive successful study execution Monitor aggregate safety and efficacy data and contribute to ongoing interpretation of clinical findings Collaborate with investigators and study sites to support enrollment, protocol adherence, and high-quality study conduct Participate in dose selection discussions, endpoint strategy, and broader clinical development planning Contribute to regulatory submissions and interactions, including briefing materials and responses to health authority questions Support publication strategy, scientific presentations, and external expert engagement Drive cross-functional alignment and facilitate efficient decision-making within study teams Maintain deep understanding of the competitive landscape and evolving cardiovascular clinical development trends Qualifications / Requirements REQUIRED: MD or PharmD required Minimum 5+ years of sponsor-side clinical development experience within biotech or pharmaceutical industry Prior experience serving as a Clinical Lead, Study Physician, Medical Monitor, or similar clinical development role Experience supporting Phase 1–3 clinical trials Strong clinical judgment and ability to apply scientific knowledge to real-world study execution challenges Experience interpreting clinical and safety data Demonstrated ability to work cross-functionally within matrixed development organizations Excellent written and verbal communication skills Ability to operate effectively in a fast-moving biotech environment

PREFERRED:

Cardiovascular clinical development experience strongly preferred Experience in hypertension, heart failure, cardiometabolic disease, renal disease, or vascular medicine highly desirable Experience interacting with investigators and clinical trial sites Experience with INDs, regulatory submissions, and FDA interactions Prior experience in small or mid-sized biotech companies Experience with novel therapeutic modalities including oligonucleotide or genetic medicine platforms is a plus

IDEAL CANDIDATE PROFILE:

The ideal candidate is: scientifically rigorous, operationally strong, decisive, collaborative, and comfortable working hands-on within clinical trial execution. This is a highly visible role for someone who enjoys being close to the science, the data, and the day-to-day realities of running impactful clinical studies.

EMPLOYMENT TYPE:

Our client is open to considering: Full-time permanent candidates Contract-to-hire candidates Contact Sandy Spinelli Email: View email address on click.appcast.io Phone: View phone number on click.appcast.io LinkedIn: Cornerstone Search Group, LLC 1200 Morris Turnpike | Short Hills, New Jersey 07078, USA Cornerstone's Privacy Policy Cornerstone Search Group considers all inquiries, resume submissions, and any other personal information submitted to us as confidential information. This information will not be shared with any parties outside of Cornerstone Search Group without your prior permission. Back To Featured Searches List word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word word mmMwWLliI0fiflO&1 mmMwWLliI0fiflO&1 mmMwWLliI0fiflO&1 mmMwWLliI0fiflO&1 mmMwWLliI0fiflO&1 mmMwWLliI0fiflO&1 mmMwWLliI0fiflO&1 #J-18808-Ljbffr Cornerstone Search Group