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Associate Scientist -Downstream Process Development

Integrated Resources, Inc ( IRI )

Job Description

We are seeking a highly motivated Associate Scientist to support purification process development during pivotal and commercial development phases. This contract role focuses on high‑throughput purification of upstream/cell culture samples and supports downstream purification characterization studies. A core part of this role is the development and optimization of high‑throughput purification assays using state‑of‑the‑art automation platforms (e.g., Tecan, Hamilton).

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The ideal candidate brings strong hands‑on laboratory skills, deep familiarity with HTP purification methods, and the ability to establish, troubleshoot, and refine automated workflows.

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Key Responsibilities

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High‑Throughput Purification & Automation

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Execute high‑throughput purification (HTP) workflows for upstream/cell culture samples to support process characterization.

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Operate, optimize, and maintain automated liquid handling systems such as Hamilton and Tecan platforms.

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Develop, qualify, and refine HTP purification assays and microscale purification methods.

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Collaborate with upstream teams to ensure timely sample processing and data delivery.

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Purification Process Development

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Contribute to experimental design and execute purification process development and characterization experiments.

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Conduct bench‑scale purification studies using chromatography, filtration, and microscale systems.

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Collect, analyze, and interpret experimental data in compliance with data integrity expectations.

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Prepare high‑quality protocols, reports, and electronic laboratory notebook documentation.

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Technical Excellence & Collaboration

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Support implementation of new purification technologies, instrumentation, and platform enhancements.

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Maintain a state‑of‑the‑art purification lab, including instrumentation readiness and workflow improvements.

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Partner with upstream, downstream, and cross‑functional colleagues as needed on development and characterization initiatives.

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Follow all compliance, training, and safety requirements.

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Qualifications / Skills / Experience

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M.S. with 2+ years or B.S. with 4+ years of relevant industry experience in chemical engineering, biochemistry, bioengineering, or related discipline.

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Expertise developing and executing HTP purification assays, including automated liquid handling systems such as Tecan, Hamilton, and microscale chromatography platforms.

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Experience with chromatography (e.g., AKTA, plate‑based), filtration, and standard downstream techniques.

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Strong analytical, documentation, and problem‑solving skills.

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Ability to work both independently and in collaborative, fast‑paced environments.

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Excellent interpersonal, verbal, and written communication skills.

Vacancy posted 2 days ago
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