Global Head of Project Delivery Operations

Global Head Of Project Delivery Operations

Syneos Health® is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities.

Every day we perform better because of how we work together, as one team, each the best at what we do. We bring a wide range of talented experts together across a wide range of business-critical services that support our business. Every role within Corporate is vital to furthering our vision of Shortening the Distance from Lab to Life®.

Discover what our 29,000 employees, across 110 countries already know.

Work Here Matters Everywhere

Why Syneos Health

• We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
• We are committed to our Total Self culture – where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people.
• We are continuously building the company we all want to work for and our customers want to work with. Why? Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives – we're able to create a place where everyone feels like they belong.

Job Responsibilities

The Head of Project Delivery Operations is a senior leadership role within Global Project Delivery, responsible for the strategic direction and operational delivery excellence of the Project Management function. In addition, this role has enterprise accountability for Clinical Supply Trial Management, Central Services (including bid support, budgeting, and proposal data management), and Trial Master File (TMF).

Accountable to the Head of Global Project Delivery, this is a senior, enterprise-critical operations leadership role responsible for setting and running the global operating framework for project delivery. The role owns delivery governance, performance management, process optimization, and capability enablement, ensuring consistent, high-quality execution at scale while supporting sustainable business growth.

Acting as the operational integrator across functions, this leader partners closely with senior clinical, commercial, finance, and delivery leaders to drive f across a complex global portfolio.

Key Responsibilities:

Global Project Management Leadership

• Provide strategic and operational leadership for the global Project Management function, ensuring consistent, high-quality delivery across regions and therapeutic areas.
• Establish and maintain global standards, frameworks, and best practices for project planning, execution, risk management, and reporting.
• Ensure effective oversight of study timelines, milestones, and deliverables across a complex, global portfolio.
• Drive a culture of accountability, proactive risk management, and continuous improvement within the project delivery organization.

• Provide leadership and governance for Clinical Supply Trial Management, ensuring alignment with study requirements, timelines, and regulatory standards.
• Partner with Clinical Operations, Supply Chain, and external vendors to ensure reliable, timely, and compliant delivery of clinical trial supplies.
• Ensure integration of clinical supply planning into overall study and program-level project plans.

Central Services Leadership (Bidding, Budgeting & Proposal Support)

• Oversee the Central Services Team responsible for supporting bids, budgeting, and proposal data management.
• Ensure accuracy, consistency, and competitiveness of study budgets, cost assumptions, and proposal inputs.
• Drive standardization of proposal data, pricing tools, and historical cost intelligence to support efficient and scalable business development.
• Partner closely with Sales, Proposals, Finance, and Operations to enable timely, high-quality bid responses.

Trial Master File (TMF) Oversight

• Provide global oversight and accountability for TMF strategy, governance, and operational performance.
• Ensure TMF completeness, quality, inspection readiness, and compliance with applicable regulatory requirements.
• Drive continuous improvement in TMF processes, systems, metrics, and inspection preparedness.

Financial & Operational Stewardship

• Partner with Finance and senior leadership to ensure strong financial management across the portfolio, including forecasting, margin delivery, and cost control.
• Ensure project-level financial rigor, including budget adherence, change control, and revenue recognition support.
• Monitor portfolio-level performance metrics and implement corrective actions as needed.

Stakeholder & Client Engagements

• Serve as a senior escalation point for complex delivery, operational, or client issues.
• Build strong, collaborative relationships with internal stakeholders across Clinical Operations, Finance, Quality, Regulatory, IT, and Commercial teams.
• Partner with client-facing leaders to support client satisfaction, retention, and growth.

Talent, Capability & Organization Development

• Lead, develop, and inspire a global, multi-layered leadership team across PM, Clinical Supply Trial Management, Central Services, and TMF.
• Drive talent strategy, succession planning, capability development, and workforce scalability.
• Promote a culture of engagement, accountability, and high performance.

Key Skills & Competencies

• Enterprise-level leadership with the ability to integrate multiple operational functions.
• Strong strategic thinking combined with hands-on operational execution.
• Deep expertise in global project delivery within a CRO or complex clinical research environment.
• Strong financial acumen, including budgeting, forecasting, and portfolio management.
• Ability to influence and collaborate across a highly matrixed, global organization.
• Excellent communication, executive presence, and stakeholder management skills.
• Proven ability to lead change, drive standardization, and scale operations.

Experience & Qualifications

• 15+ years of extensive experience in Project Management leadership within a CRO, biopharmaceutical, or clinical research environment.
• Demonstrated experience overseeing global, multi-study portfolios.
• Experience with Clinical Supply Trial Management, TMF operations, and proposal/bid support strongly preferred.
• Proven track record of leading large, global teams and senior leaders.
• Advanced degree in life sciences, business, or a related field preferred.

At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements.

Salary Range:

$204,600.00 - $378,600.00

The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate's qualifications, skills, competencies, and proficiency for the role.

Get to know Syneos Health

Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.

No matter what your role is, you'll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.