Postdoctoral Fellow-MSH-32076-153

Job Description Salary: Per UAW starting salary effective 7/1/25 $74,692 Department: 866 – Department of Immunology and Immunotherapy Location: Icahn Building 12 th floor-1425 Madison Ave, New York, NY 10029 Department website: Laboratory website: Qualifications The Labanieh Lab is affiliated with the Department of Immunology and Immunotherapy, the Icahn Genomics Institute (IGI), and the Precision Immunology Institute (PrIISM). We are part of a collaborative community of bold thinkers with world‑renowned expertise in basic sciences and cutting‑edge clinical care. The department is supported by state‑of‑the‑art technology cores. In addition to submitting an application through candidates are encouraged to send the following directly to Dr. Labanieh (View email address on click.appcast.io): Cover letter (indicating earliest and preferred start dates) Updated Curriculum Vitae or Biosketch Brief statement of research interests ( Contact information for three references This position is covered by a collective bargaining agreement between the ISMMS and the Sinai Postdoctoral Organizing Committee - UAW. Wages and benefits: See Article 5 and 13 of the collective bargaining agreement found online at Our mission at Mount Sinai Health System is to provide compassionate patient care with seamless coordination and to advance medicine through unrivaled education, research, and outreach in the diverse communities we serve. Mount Sinai Health System is committed to diversity and equal opportunity. Responsibilities The Louai Labanieh Lab is seeking motivated postdocs to develop, characterize, and test novel biotechnology platforms for: i) the precise in‑vivo delivery of genetic cargo and ii) regulation of immune cell function. These projects focus on safer and more effective cell therapies (e.g., CAR‑T) and gene therapies for cancer and beyond. The interdisciplinary lab spans synthetic biology, immune cell engineering, protein engineering, and immunology, with a goal toward clinical translation. Postdoctoral fellows will gain extensive experience with cutting‑edge methodologies in T cell engineering, gene editing, viral vector engineering, single‑cell omics, and in‑vivo gene delivery. This is a unique opportunity to develop next‑generation cell and gene therapies that overcome clinical challenges and provide curative options for patients with cancer and other debilitating diseases. The candidate should have a PhD and/or MD in bioengineering, immunology, cellular/molecular biology, cancer biology, or a related field, and experience in wet‑lab research. Prior experience in cell engineering, synthetic biology, T cell biology, or protein engineering is highly desirable but not required. We encourage applications from individuals with a strong foundation in related fields who are eager to learn and contribute to our research program. Lead independent research projects, including hypothesis development, experimental design, execution, and data interpretation. Design and engineer novel synthetic constructs to precisely control immune cell function. Analyze, visualize, and interpret data. Document and maintain raw data, analyzed data, constructs, and protocols in an organized manner and share them with others when needed. Engage in regular meetings with the Principal Investigator for project updates, scientific discussions, and career mentorship. Present research findings at scientific conferences and contribute to the publication of manuscripts and grant proposals. Train and mentor junior lab members. Assist in maintaining lab functions. Perform mammalian cell culture, viral transduction, and molecular cloning. Apply and develop methods in protein biochemistry. Utilize advanced microscopy techniques, including confocal microscopy. Conduct functional assays to assess immune cell activity (e.g., cytotoxicity assays, proliferation assays, ELISA). Perform in‑vivo experiments in mouse models to evaluate the safety and efficacy of bioengineered constructs and investigate underlying biological mechanisms. Analyze immune cell populations by flow cytometry, RNA‑seq, and ATAC‑seq. Collaborate effectively with members of the research team. Communicate clearly and concisely, both orally and in writing, and adhere to project deadlines. Maintain strict adherence to laboratory safety policies and procedures. About Us The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We work together to transform healthcare and promote inclusive practices that ensure fair access to opportunities and support the success of every individual. Equal Opportunity Employer The Mount Sinai Health System is an equal‑opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization. Compensation Statement Mount Sinai Health System (MSHS) provides a salary range to comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $72,500 - $80,000 annually. Actual salaries depend on a variety of factors, including experience, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits. #J-18808-Ljbffr Mount Sinai Health System