Lead Scientist, Modeling & Simulation
$112k - $164kEntegris Inc
Job Title: Lead Scientist, Modeling & Simulation Job Description: The Role: Entegris is currently seeking a Modeling & Simulation (M&S) Engineer to join our Digital Solutions Enablement team. In this role, you will perform simulations of products and product derivatives using established models. You will interpret the results and validate model predictions against empirical data. You will then deploy validated models for business users through AI-enabled tools and standard operating procedures (SOPs), supported by training and first-line application support. You will also work with business unit R&D teams and the Core M&S Team to translate scientific and engineering challenges into clear modeling requirements and fit-for-purpose solutions. What You’ll Do: Perform simulations. Apply established models to conduct multiphysics simulations, computational fluid dynamics (CFD), finite element analysis (FEA), involving fluid flow, heat transfer, structural mechanics, and design for products and product derivatives. Analyze and interpret results. Deploy models and workflows. Make standardized M&S capabilities accessible to R&D users through AI-enabled tools and standard procedures to help them to address technical challenges. Validate simulations. Use simulation results to validate models against empirical data and improve prediction. Translate R&D needs into modeling requests. Partner with business unit R&D teams to understand technical challenges and define executable M&S requests with clear inputs, assumptions, and expected outputs. Train and support users. Develop application guidance, deliver training, and provide first-line support so researchers can use models and workflows effectively. Connect user needs with core development. Capture unmet needs, recurring issues, and application gaps, and provide actionable feedback to the Core M&S Team. Contribute to AI/Digital Scientists. Collaborate with modeling specialists and R&D users to develop AI-enabled tools that support scientific and engineering workflows. What We Seek: Minimum Qualifications Master’s degree in mechanical engineering, chemical engineering, aerospace engineering, or a related engineering field Five years of relevant industry experience Strong knowledge of fluid dynamics, heat transfer, engineering design, and numerical modeling Three years of experience using commercial simulation software, such as Ansys, Abaqus, or COMSOL, or open-source software, such as OpenFOAM Proficiency with CAD software, such as SolidWorks or Creo, including geometry preparation for simulation Experience using high-performance computing (HPC) clusters and scaling simulations in cloud environments Experience applying modeling and simulation to scientific or engineering problems and translating R&D questions into clearly defined modeling requirements Experience validating models and collaborating with product development or laboratory teams to define and obtain relevant experimental data Ability to deploy established models and workflows for researchers with varying levels of modeling experience Ability to train technical users and troubleshooting modeling or scientific application issues Strong written and verbal communication skills and the ability to collaborate across R&D teams and with modeling specialists Ability to identify limitations in existing tools, capture user needs, and communicate actionable recommendations to guide future development Preferred Qualifications Industry experience in the semiconductor, aerospace, or oil and gas sectors Experience with manufacturing process simulation, including blow molding or injection molding Experience automating simulation or engineering workflows using Python, MATLAB, or C++ Familiarity with AI-enabled scientific workflows or experience contributing to AI/Digital Scientist development Outstanding Candidates Will Have: A track record of enabling R&D teams outside specialist modeling groups to adopt standardized modeling workflows Hands-on experience developing AI assistants or agents for scientific or engineering applications Demonstrated success converting recurring user questions and unmet needs into improvements to models, tools, or scientific workflows A strong commitment to simulation-driven design and continuous technical learning Demonstrated commitment to the company’s long-term success and the ability to tackle complex challenges Exemplifies Entegris’ core values: Integrity, Innovation, Teamwork, and Dedication to Excellence Why Work at Entegris Lead. Inspire. Innovate. Define Your Future. Not everyone who works for a global company shares the same background, experiences and perspectives. We leverage the differences of our employees to bring new ideas to the table. Every employee throughout the company is encouraged to share input on projects and initiatives. Our decision-making process is truly a collaborative effort as we realize there are leaders at every level of the organization. We put our values at the core of how we operate as an organization — not just when it’s convenient, but in a lasting and meaningful way. We want the time and energy you spend here to have a positive impact on your life inside and outside of the office. What We Offer: Compensation: The salary range for this position is $112,000 - $164,000 per year. Final offers will be based on the candidate's overall skills and qualifications for the role. Generous 401(K) plan with an impressive employer match Excellent health, dental, and vision insurance packages to fit your needs Flexible work schedule and 11 paid holidays a year Paid time off (PTO) policy that empowers you to take the time you need to recharge Education assistance to support your learning journey Values-driven culture with colleagues who rally around People, Accountability, Creativity, and Excellence Entegris does not provide immigration-related sponsorship for this role. Do not apply for this role if you will need Entegris immigration sponsorship (e.g., H1B, TN, STEM OPT, etc.) now or in the future. At Entegris we are committed to providing equal opportunity to all employees and applicants. Our policy is to recruit, hire, train, and reward employees for their individual abilities, achievements and experience without regard to race, color, religion, sexual orientation, age, national origin, disability, marital or military status. At Entegris, we want you to be part of our culture, which values your unique talents, skills, and experiences. We believe what we do is as important as how we do it. People at our company bring their true selves to work, and are appreciated not only for what they do, but for who they are. This plus the technical complexity of our products and solutions means you can be sure your work is both challenging and changing the world for the better. Learn more about why people enjoy working at Entegris. #J-18808-Ljbffr Entegris, Inc.
- MITRE invites an experienced Lead Modeling and Simulation Analyst to join the M&A division. You will partner with stakeholders to develop advanced modeling, simulation, and analytical tools, integrating math, physics, engineering, and programming to produce actionable...Suggested
$130k - $180k
...Engine in Cambridge, MA. The Opportunity CHI is hiring a Lead Simulation Scientist to build and own the computational backbone of our fusion platform... ...maintain equation-of-state, opacity, and material-strength models for target materials under extreme conditions. Use...Suggested- ...objectivity and integrity at our core, we lead federally funded research and... ...field. MITRE Technology and Engineering Modeling and Analysis (M&A) Division brings together... ...solutions. M&A is seeking modeling and simulation engineers and operations research analysts...SuggestedWork experience placementLocal areaImmediate start
- Cambridge Heavy Industries (CHI) is hiring a Lead Simulation Scientist to build the computational backbone of our fusion platform in Cambridge, MA. You will develop hydrocode and PIC simulations, validate against experiments, and translate results into design decisions...Suggested
- Role Overview As a Conveyor Solutions & Simulation Lead, you will be responsible for developing, optimizing, and standardizing the conveyor... .... By developing clearer standards, reusable design guidance, modeling assumptions, and optimization methods, this role enables...Suggested
- ...Electromagnetic Systems (GA-EMS) is seeking an experienced Lead Scientist, Optical Systems to support the development, integration,... ...payloads. Process and analyze test data using computational models, simulations, and engineering software. Develop measurement...Full timeWorldwide
- ...Research Scientist Position at Basis Research scientists lead Basis' efforts to develop a deeper understanding of the... ...both having and discovering world models are central to intelligence,... ...such as AutumnBench, physical and simulated robotics benchmarks, and the Abstract...Full timeWork at officeImmediate start
$135k - $170k
...Hydrogeologist to join our Water Practice Group. The role focuses on water supply well development, environmental investigations, groundwater modeling, and stakeholder coordination. Salary range is $135,000-$170,000 per year, with final salary determined by education, experience,...Work at office- Berkshire Grey, Inc. is seeking a Conveyor Solutions & Simulation Lead to design, optimize, and standardize the conveyor architecture for... ...decisions across engineering teams. Responsibilities include leading modeling efforts, validating assumptions, and ensuring...
$146k - $236.5k
...-backed stealth AI x bio company, is seeking a Sr. Scientist / Principal Scientist, Molecular Simulations. Here you will build the physics layer of a drug development... ...You will work at the interface of structure-based modeling and generative ML, turning simulation output into...- Job title : Modeling Scientist Location: Cambridge, MA About the job The Translational Disease Modeling (TDM) group at Sanofi is seeking to... ...modeling scientist to support its portfolio in R&D. Modeling and simulation (M&S) plays an important role in drug development at Sanofi....Internship
- Flagship Pioneering, Inc. seeks a Sr. Scientist/Principal Scientist in Molecular Simulations to build the physics layer of our AI-driven drug-design platform... ...synthesis, operating at the interface of structure-based modeling and generative ML. You will run MD, enhanced...
- ...quality biotherapeutics development go hand in hand. As a Scientist, PK/PD Modeling & Simulation, you will be responsible for developing, validating, and... .... You will work closely with internal cross-functional leads (clinical pharmacology, nonclinical, clinical...
- A leading environmental consulting firm is seeking a Principal Consultant to join its Aviation Environmental & Sustainability group in a remote or hybrid role. You will manage AEDT modeling teams and oversee complex environmental projects, requiring extensive experience...Remote job
- EMD Serono, Inc. in the United States is seeking a Principal Scientist, LNP Discovery Biology to lead assays for the in vivo CAR-T program within the Research Unit Neuroscience & Immunology. The role sits at the interface of LNP delivery and immunology and collaborates...
- ...and materials testing. We seek a Principal Fusion Researcher to lead laser-system construction, target design, and experiments in... ...fast ignition experience, and hands-on laser experience across diagnostics and simulations. #J-18808-Ljbffr Cambridge Heavy Industries Inc.
$114.1k - $211.9k
...and scientifically accomplished Translational Biomarker Strategy Lead to serve as the biomarker representative and strategic advisor... ...milestones. Develop integrated biomarker plans encompassing assays, models, samples, analyses, timelines, and external partnerships....Local areaFlexible hours- ...BioMedical Research, Inc. (NIBR) in Cambridge, MA seeks an in vivo scientist to join the Oncology Pharmacology team. You will design and... ...anti-tumor efficacy and PK/PD studies in CDX, PDX, and syngeneic models to advance early drug discovery and translational data. The...
$120 - $140 per hour
A leading provider in pharmaceutical research is seeking a Senior Scientist to act as a DMPK project representative. The role involves providing scientific leadership... ...extensive experience in ADME principles and PK/PD modeling, strong communication skills, and the ability...Hourly payContract work- EMD Serono, Inc. is seeking an In Vitro Principal Scientist to shape the in vitro strategy for tumor immunology initiatives. You will execute experiments and lead discovery teams, coordinating across oncology projects to advance candidates through early development. The...
- Berkshire Grey is seeking a Conveyor Solutions & Simulation Lead to develop, optimize, and standardize the conveyor system architecture and simulation methods that support the Stride platform. You will collaborate with Solutions Architecture, Applications Engineering, Controls...
$119.7k - $222.3k
...motivated PK Sciences representative to lead the development and use of artificial... ..., Drug Disposition (ADME, BA), Modeling & Simulation (M&S), and Operations through PK science... ...strategy, to be considered for Principal Scientist II. 4+ years of experience to be considered...$113.87k - $165.11k
...relationship with and support of KRI Senior R&D Engineers/Scientists for government and industry contracts will be required.... ...related R&D programs. Experience developing or integrating simulation-based models, including physics-based, network-based, agent-based, or...Work experience placementWork at office- ...we are seeking a Senior Machine Learning Scientist to help build and maintain our cutting-... ...focus on deep neural network architectures, model training, and inference-time... ...traditional computer vision, 3D graphics and simulation, robotics, and MLOps.Primary Responsibilities...Work experience placement
- Regeneron is seeking a Senior Toxicologist to lead nonclinical development programs with regulatory oversight and cross‑functional collaboration... ...to design, conduct, and report studies in rodent and non‑rodent models while aligning with FDA/ICH/EMEA guidelines. Ideal candidates...
- ...Pharmaceuticals, Inc (USA) is seeking a Senior Toxicologist to lead nonclinical development programs with guidance from their supervisor... ...toxicology studies and related pharmacology work in rodent and non-rodent models. #J-18808-Ljbffr Regeneron Pharmaceuticals, Inc (USA)
$142k - $215.2k
...globe. Your Role The Principal Scientist, Translational Quantitative... ...for developing and executing Model Informed Drug Development (... ...compound progression decisions from lead optimization to clinical... ...of innovative modeling and simulation platforms/strategy that ensure...Flexible hours- Principal Scientist, Translational Modeling & Decision Science Cambridge, MA USA About the Role Pioneering Intelligence (PI) builds AI systems that accelerate translational decision making. This role bridges the gap from capability to impact by leveraging PI technologies...
$157k - $213k
...calling to “Reimagine Possible”, we are leading the charge toward a world in which... ...highly motivated and detail-oriented Scientist with strong expertise in bioanalytical... ...biodistribution, etc.) Hands-on experience with modeling and simulation is a plus Pay Range Disclosure...Temporary workSummer workWork at officeLocal area- ...hardware and software engineers to advance AI-powered robotics across diverse applications. This role focuses on building foundation models, such as vision-language-action models, to enable physical agents to perceive, plan, and act with dexterity. You will work on...
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Lead Scientist, Modeling & Simulation. Be the first to apply!
- drug safety scientist Bedford, MA
- senior scientist Bedford, MA
- scientist biology Bedford, MA
- manufacturing scientist Bedford, MA
- water quality scientist Bedford, MA
- lab scientist Bedford, MA
- research scientist Bedford, MA
- deep learning scientist Bedford, MA
- machine learning research scientist Bedford, MA
- qc scientist Bedford, MA

