Senior Program Manager - Security and Performance
$147k - $185kInterSystems
InterSystems is a global leader in healthcare data management and interoperability, providing mission-critical technology that powers hospitals, health systems, and national infrastructures worldwide. Our products underpin trusted healthcare and financial systems where performance, availability, and security are non-negotiable. As a Senior Program Manager, you lead large-scale, complex, cross-functional initiatives across product, engineering, cloud, and AI. You operate across organizational boundaries, translating objectives aligned to corporate strategy into coordinated, measurable outcomes. You support and operationalize the security strategy across the portfolio, ensuring effective execution through structured programs. Security and performance are horizontal capabilities across our stack. You partner with product, engineering, and architecture to maintain consistent execution across the portfolio. Key Characteristics
- Thrives in high ambiguity, competing priorities
- Owns outcomes at a program level
- Connects strategy to execution (systems thinker)
- Influences without authority
- Execution-focused; manages complexity
- Communicates clearly across technical and business audiences
- Program Strategy, Execution & Delivery
- Execute against existing program direction and strategic priorities,
- Lead concurrent projects to deliver program objectives
- Coordinate execution with program managers across cloud, database,
- Align scope, priorities, and dependencies to enable delivery
- Cross-Functional Leadership & Stakeholder Management
- Orchestrate work across product, engineering, architecture, compliance, and
- Serve as integration point for dependencies, timelines, and deliverables
- Manage senior stakeholders, including executive engagement
- Communicate progress, risks, and decisions to support leadership action
- Run structured updates and program reviews to maintain alignment
- Program Performance, Health & Continuous Improvement
- Monitor program performance and health against established KPIs,
- Manage risks, issues, and dependencies; escalate when needed
- Maintain clear program visibility and enforce accountability
- Improve execution, coordination, and operational effectiveness
- 10+ years leading large-scale, complex, cross-functional programs
- Strong fundamentals in planning, scheduling, dependency and risk management
- Experience managing performance to KPIs and driving accountability
- Experience in cloud, healthcare, or enterprise technology environments
- Proven ability to influence senior stakeholders without direct authority
- Strong communication and leadership skills
- PMP or equivalent certification a plus
- Medical, vision, and dental insurance
- Short-term and long-term disability, and life insurance
- 401(k) Profit Sharing Contribution
- Paid Time Off and Holidays
- Parental Leave
- Tuition reimbursement
$147,000—$185,000 USD
About InterSystems InterSystems, a creative data technology provider, delivers a unified foundation for next-generation applications for healthcare, finance, manufacturing, and supply chain customers in more than 80 countries. Our data platforms solve interoperability, speed, and scalability problems for large organizations around the globe to unlock the power of data and allow people to perceive data in imaginative ways. Established in 1978, InterSystems is committed to excellence through its 24×7 support for customers and partners around the world. Privately held and headquartered in Boston, Massachusetts, InterSystems has 38 offices in 28 countries worldwide. For more information, please visit InterSystems.com [$121k - $148k
...is a global leader in healthcare data management and interoperability , providing mission... ...the industry — where availability and security are non‑negotiable requirements. As a... ...including experience, education, skills, and performance. Other compensation may include a...SeniorPerformanceTemporary work$145.9k - $234.2k
The Role Moderna is seeking a Senior Technical Program Manager (TPM) to drive project and program management... ...Advance good infrastructure and security practices and culture Partner Collaboration... ...certifications, experience, skills, performance, and business or organizational...SeniorPerformancePermanent employment- ...Title: Project Manager/ Sr Program Manager Location: Cambridge, MA Duration: 6 to 12 Contract... ...for the Diranersen program. Strong performance in this role enables the Diranersen... ...complex, global matrix and influence senior stakeholders across R&D and Commercial...SeniorPerformanceContract work
- Draper in Cambridge, MA, seeks a Project Manager to lead lifecycle management and supplier execution for complex electronic components... ..., ensuring adherence to cost, schedule, and technical performance standards. The ideal candidate has at least 7 years of experience...SeniorPerformance
- Draper is seeking a Program Manager 2 in Cambridge, MA, to lead programs for Air Force and Missile Defense Strategic Systems. You will manage... ...projects while ensuring customer expectations and technical performance are met, providing leadership oversight and developing...SeniorPerformance
- ...delivers real business value with AI. What You’ll Do The Manager / Sr. Manager of Strategic Security Programs leads the identification, prioritization, and... ...progress and accountability Translate program performance into clear insights, highlighting risks, gaps, and...SeniorPerformancePermanent employmentFlexible hours
- Draper Labs, based in Cambridge, MA, is seeking a Program Manager 2 to oversee complex projects in Air Force and Missile Defense. You'll... ...significant programs while ensuring cost, schedule, and technical performance. The ideal candidate has extensive experience in project...SeniorPerformance
$151.2k - $226.8k
Overview The Tech Program Manager II leads complex, multi workstream programs that deliver strategic... ...success criteria in collaboration with senior stakeholders. Manage multiple... ...delivery governance. Manage external partner performance and contracts supporting program...SeniorPerformanceFull timeWork experience placementWork at officeFlexible hours$155k - $185k
...health and fitness wearable on a mission to unlock human performance. We empower our members to improve their health and perform... ...understanding of their bodies and daily lives. We are looking for a Senior Program Manager, SaMD to join our growing team and help scale the...SeniorPerformanceFull timeWork at officeRelocation$125k - $165k
...Program Manager (CapEx) At WHOOP, we're on a mission to unlock human performance. WHOOP empowers members to perform at a higher level through a deeper understanding of their bodies and daily lives. As a CapEx Program Manager on the Technical Program Management (TPM...SeniorPerformanceFull time$170k - $200k
At WHOOP, we’re on a mission to unlock human performance and healthspan. WHOOP empowers members to perform at a higher level... ...analytics to deliver actionable insights. WHOOP is seeking a Senior Materials Program Manager to drive end-to-end materials readiness and supply...SeniorPerformanceFull timeWork at officeRelocation$125k - $213k
...Lead athenahealth’s global physical security and executive protection programs to protect people, facilities,... ...of 24/7 security operations. The Senior Manager, Global Security, will report to... ...delivered security operations, setting performance metrics and ensuring contractual...SeniorPerformanceFull timeTemporary workWork at officeRemote workWorldwideRelocation$150k - $195k
...At WHOOP, we're on a mission to unlock human performance. WHOOP empowers members to perform at a higher level through a deeper... ...understanding of their bodies and daily lives. As a Senior Technical Program Manager on the Manufacturing Program Management team, you'll...SeniorPerformanceFull timeContract workWork at officeRelocation- ...striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all... ...and communities safe across every care setting. As the Sr. Program Manager for Infection Control focused on High-Level Disinfection & Sterilization...SeniorPerformanceRemote work
$185k - $277k
...Hybrid/Remote Job Overview The Senior Manager of Enterprise Security is a technical people leader... ...SecDevOps and continuous compliance programs, and leads a living, learning, and... ...Builds, coaches, and retains a high-performing, technically elite security team. Creates...SeniorPerformanceWork at officeRemote work$92.2k - $115.3k
...opportunity for a dynamic, results-oriented Senior Supplier Program Manager (SPM) to join the Supply Chain team.... ...suppliers and monitor their performance against deliverables documented in a... ...have the ability to obtain, a Secret Security Clearance. Preferred Qualifications...SeniorPerformanceTemporary workFor contractorsWork experience placementFor subcontractorCasual workWork at office- NWN seeks a Program Manager in Boston to manage complex programs and strategic accounts, driving financial performance and client outcomes. The role requires 10+ years of IT project management experience, a Bachelor’s degree, and strong leadership skills. This position...SeniorPerformance
- Clearance Jobs seeks a Project Manager in Cambridge, MA, to lead... ...management for complex procurement programs. You will drive part... ...Systems Programs, ensuring project performance across various complex... ...and must obtain a government security clearance. This position supports...SeniorPerformance
$90k
...Job Summary Manage and oversee a high-volume 24/7 Command Center supporting approximately 73 properties... ...communication • Conduct training, audits, and performance management Requirements • 5+ years command center or security operations leadership • Experience managing...SeniorPerformanceFull timeAll shiftsShift work- Overview We are seeking a Senior R&D Program Manager for the Navigation Software portfolio within Digital R&D, located in Boston, MA and Gieres... ...leadership decisions. Lead financial planning and performance reviews for the platform in partnership with PMO Operations...SeniorPerformanceFor contractors
- ...Cambridge, Massachusetts is seeking a Project/Program Manager responsible for leading lifecycle... ...partner with various teams to drive performance and customer satisfaction. Applicant... ...Applicants selected will require a government security clearance. #J-18808-Ljbffr The...SeniorPerformance
- ...Who You Are TetraScience is seeking an elite Technical Program Manager dedicated to a single, high-profile account in Cambridge,... ...measurable value. Establish KPIs and success metrics , tracking performance against commitments and ensuring accountability across...SeniorPerformanceWork experience placementImmediate start
- ...MassHealth Chief Medical Officer/Director of OCA, or designee, the Senior Program Manager works directly with the MassHealth Quality Office and... ...of quality and health equity measures Setting of performance targets Establishing and testing performance assessment methodologies...SeniorPerformanceWork experience placementWork at office
- ...provide exceptional care. We believe that high-performing teams drive groundbreaking medical... ...General Brigham.Job SummaryReporting to the Manager, Patient Safety Systems and Programs Administration, Mass General Brigham, the Senior Program Manager, Patient Safety and Risk...SeniorPerformanceRemote work
- Hirebridge is looking for a Facilities Operations Manager in Boston, Massachusetts. The role is... ...projects, and leading operational training programs. This position demands a proactive approach to ensure optimal performance of mechanical, electrical, and plumbing systems...SeniorPerformance
$193k - $220.3k
Senior Manager, Technical Program Manager AI / ML Are you interested in leading programs that deliver on critical... ...with large cross-functional teams, secure commitments on deliverables, and... ...This role is also eligible to earn performance based incentive compensation, which...SeniorPerformanceFull time$150k - $215k
WHOOP is on a mission to unlock human performance and healthspan. Our Health Machine Learning team develops the algorithms and... ...required to deliver world‑class health products. As a Senior Technical Program Manager, you will serve as the connective tissue across the...SeniorPerformanceFull timeWork at officeRelocation$119.6k - $215.4k
...driving complex technical programs from vision to reality?... ...applications with unmatched performance, compliance, and economics... ...Partner with the best As a Senior Technical Program Manager, you will require... ...Akamai to build, deliver, and secure their digital experiences...SeniorPerformancePermanent employmentWork experience placementWork at officeWork from homeWorldwideFlexible hoursShift work$116k - $145k
Join to apply for the Senior Technical Program Manager role at DigitalOcean . Dive in and do the best work of your career at DigitalOcean. Journey... ...most interesting people in the industry. We are a high‑performance organization that will always challenge you to think big...SeniorPerformanceFull timeLocal areaRemote workWorldwideFlexible hours$118.5k - $189.5k
Job Description: Our Opportunity: Chewy is looking for a Senior Program Manager to own the RX-segmented supply chain for Delivery Experience... ...delivery experience and establish mechanisms to inspect performance and drive continuous improvement Lead cross-functional initiatives...SeniorPerformanceFull timeLocal areaFlexible hours
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Program Manager - Security and Performance. Be the first to apply!
- program coordinator remote Boston, MA
- head of program management Boston, MA
- agile transformation program manager Boston, MA
- program supervisor Boston, MA
- executive program manager Boston, MA
- staff program manager Boston, MA
- service program manager Boston, MA
- programme manager Boston, MA
- international program coordinator Boston, MA
- project program manager Boston, MA



