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Principal Chemist

LGC Group

LGC Biosearch Technologies seeks a Principal Oligonucleotide Chemist to lead product development, synthesis, and process innovation across their Petaluma Innovation Hub. This senior role combines hands-on laboratory work with strategic project leadership, mentorship, and customer collaboration to advance oligonucleotide chemistry capabilities.

Responsibilities

  • Lead oligonucleotide new product development and customer co-creation projects from concept through delivery
  • Design and execute synthesis, purification, and analytical characterization methods; troubleshoot complex issues
  • Perform hands-on laboratory work including automated and manual oligonucleotide synthesis and characterization
  • Develop data-driven experimental strategies and lead technology transfer into operations and manufacturing
  • Mentor scientists in oligonucleotide chemistry and foster collaborative, growth-oriented team environment

Requirements

  • Ph.D. in Synthetic Organic Chemistry, Chemical Biology, or related field
  • Minimum 15 years industry experience in oligonucleotide synthesis and process development
  • Expertise in solid-phase oligonucleotide synthesis, modification, and analytical characterization
  • Demonstrated project management and cross-functional team leadership capability
  • Strong ability to design, optimize, and troubleshoot manufacturing development processes
  • Excellent technical communication skills for internal and external audiences
Vacancy posted 1 day ago
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