Senior Fluidics Engineer
Exthymic
We are scientists, engineers, and operators who have spent our careers inside cell therapy manufacturing. We have built the platforms, scaled production, and watched these treatments fail to reach the patients who need them. We are building the technology to close that gap. If this is work you want to do, read on. About You You are a hands-on fluidics engineer with a genuine love for making things work at small scales. You move comfortably between CAD and the bench, and you take pride in building systems that are reliable, reproducible, and ready for the next stage of development. You have direct experience developing and testing fluidic subsystems within life science instruments, from early breadboard concepts through prototyping, integration, and verification. You are self-directed, comfortable with ambiguity, and energized by cross-functional collaboration Own fluidic subsystem design and development - Design, prototype, and iterate on the fluidic architecture of our cell processing platform, including pumps, valves, manifolds, flow cells, and disposable cartridge interfaces, from concept through bench validation. Build and execute test protocols for fluidic performance - Author and run characterization tests covering flow rate accuracy, pressure regulation, dead volume, carryover, and sterility boundary integrity. Own the data, document in design history records, and drive iteration. Collaborate across hardware, biology, and systems teams - Work directly with cell biologists to understand how fluidic conditions affect cell health and process yield, and translate those findings into engineering requirements and design changes. Support instrument integration and system-level testing - Debug fluidic behavior in the context of the full instrument, contribute to integration test execution, and drive failures to resolution. Contribute to design control and documentation - Maintain engineering drawings, BOMs, test reports, and design rationale as living artifacts of the development process. Qualifications Bachelor\'s or advanced degree in Mechanical Engineering, Biomedical Engineering, Chemical Engineering, or a closely related discipline. Typically at least 4–8 years of hands-on experience designing and testing fluidic systems in an instrument development or life science product context. Proficiency with CAD software (SolidWorks, Onshape, or equivalent) for fluidic component and manifold design. Direct bench experience with pumps, solenoid and proportional valves, pressure sensors, and flow measurement. Experience authoring and executing structured test protocols, capturing data, and writing engineering reports. Comfortable handling primary human cells for functional testing of fluidic subsystems Demonstrated ability to work independently with incomplete requirements and iterate rapidly on physical hardware. Preferred Qualifications Experience with microfluidic chip design and fabrication. Familiarity with sterile fluid path design, aseptic connections, and biocompatibility requirements for cell-contact materials. Experience designing disposable fluidic consumables, including cartridge interfaces and single-use flow paths. Background working in an early-stage startup or pre-product R&D environment. Exposure to design control processes (DHF, design reviews, FMEA) in a regulated or semi-regulated development context. Familiarity with computational fluid dynamics (CFD) tools for pre-prototyping analysis. Experience in the cell therapy, diagnostics, or genomics instrument space is a plus. Familiarity with AI-assisted design, simulation, documentation, or troubleshooting tools. We offer our employees comprehensive benefits, including medical, vision, and dental coverage, as well as retirement savings plans. Optional benefits include Accident and Term Life offerings. Agencies We work directly with candidates and do not accept unsolicited resumes or referrals from recruitment agencies, search firms, or staffing companies. Any resumes submitted by an agency without a signed agreement in place will be considered the property of Exthymic and no fee will be owed. If you are interested in partnering with us on a future search, please contact our HR team directly. #J-18808-Ljbffr Exthymic
- Exthymic is seeking a hands-on Fluidics Engineer in San Diego, California. You will design fluidic subsystems for cell processing platforms and support instrument integration, collaborating closely with biology teams. Candidates should have a relevant degree and 4-8 years...Senior
$130k - $144k
...life. Our revolutionary super resolution microscope and fluidic systems stand at the forefront of advancing cellular studies... ...a molecular level. We are seeking a versatile Senior Systems Integration Engineer who thrives at the intersection of hardware, software,...SeniorFor contractorsFlexible hours$130k - $140k
Senior Mechanical Engineer, Machine Design Location: San Diego, CA Job Type: Full-Time $130,000 - $140,000 Machine Design Own the design of... ...for chemical compatibility and biocompatibility Integrate fluidic subsystems with thermal and mechanical assemblies Develop...SeniorFull time$130k - $140k
Senior Mechanical Engineer, Chassis & Enclosures Location: San Diego, CA Job Type: Full-Time Salary Range: $130,000 - $140,000 Position Overview... .... You will work closely with electrical, optical, fluidics, and manufacturing teams to ensure reliable, serviceable,...SeniorFull timeContract work$158k - $197k
...collegiality, honesty, objectivity, and openness. We are seeking a Senior Staff Electrical Engineer who will play a critical technical leadership role in the... ...Collaborate closely with systems, mechanical, optical, fluidics, and firmware teams to ensure seamless integration...SeniorFull timeFlexible hours- ...anywhere. If you're the best at what you do, come work at Innophase IoT! Job Summary We are seeking a highly experienced Senior SoC STA Engineer to own chip-level timing sign-off for next-generation SoC designs. In this role, you will work closely with RTL Design,...SeniorFull time
$142.2k - $265.6k
Northrop Grumman Corp. (JP) is seeking a Senior Systems Engineer in San Diego, CA, to develop and manage engineering requirements. Ideal candidates will possess a strong background in systems engineering and leadership capabilities. This role involves collaboration across...Senior$105k - $200k
...pipeline-deterministic aircraft and mission simulation, HIL/VIL integration, CI/CD, automated flight qualification testing, and release engineering. Our goal is simple: make AI fly-safely, repeatably, and fast. As a Modeling & Simulation Engineer, you will be...Senior$160k - $240k
Shield AI is seeking an experienced Mechanical Engineer in San Diego. You will design complex mechanisms for autonomous UAVs, manage the full design process, and collaborate with cross-functional teams. Required qualifications include a B.S. in Mechanical/Aerospace Engineering...Senior- ...Digital Recruitment is seeking a Mask Layout Designer for a hybrid position in San Diego, CA. You will be part of a world-class engineering team focused on RF, analog, and mixed-signal design for advanced SoC products. Responsibilities include detailed transistor-level...Senior
$163.3k - $290.1k
A leading technology company is seeking an RFIC Layout Engineer to join their Wireless SoC Radio Team in San Diego, California. This role involves designing energy-efficient CMOS radios and requires a BS degree with over 10 years of relevant experience. Key responsibilities...Senior$140k - $180k
...Join our fast‑paced and passionate team as a Senior PCB Layout Engineer 4. In this role, you will take ownership of complex PCB designs, collaborate closely with electrical and mechanical engineers, and help establish layout practices that support our mission and growth...SeniorFull timeLocal area$120k - $180k
Elevate-Semiconductor-1 in San Diego is seeking a highly skilled Senior Analog Layout Engineer to develop state-of-the-art integrated circuits (ICs). The role includes performing physical layout and verification of complex circuits, collaborating with a cross-functional...Senior$177k - $265.6k
Northrop Grumman Corp. (AU) seeks a Staff Guidance Navigation and Control Engineer in San Diego, CA. This role involves designing and testing algorithms to enhance guidance and navigation systems, requiring a strong STEM background. Candidates must possess an active US...Senior$177k - $265.6k
Northrop Grumman Corp. (JP) in San Diego is seeking a Staff Guidance Navigation and Control Engineer to work on advanced systems that revolutionize technology. Candidates must hold a Bachelor's degree in a related STEM discipline and possess extensive experience in guidance...Senior- A leading technology company in California, San Diego, is looking for a highly skilled designer to join their wireless silicon development team. You will work with SoC architects to define features for CPU-based subsystems in high performance, low power wireless SoCs. Responsibilities...Senior
- ...decisions of highest importance to the nation. The Advanced Wireless & SATCOM Department which is part of the MITRE Technology and Engineering Infrastructure, Networking, and Communications Division, has as its mission to provide premier communications network engineering...SeniorWork experience placementInternshipLocal areaImmediate start
$57.74 - $83.44 per hour
A healthcare organization is seeking an IAM Systems Developer II based in San Diego, California. The ideal candidate will build and optimize IAM solutions, integrate cloud IAM services, and ensure compliance with security standards. Candidates must have a Bachelor's degree...SeniorHourly pay- Apple Inc. is looking for an experienced engineer in San Diego to work on the client-side of iCloud services. Your responsibilities will include building secure protocols, collaborating with security and privacy teams to ensure the end-to-end encryption of user data, and...SeniorFull time
$85k - $140k
A leading engineering solutions provider located in San Diego is seeking a Senior LabVIEW Engineer to join their team. In this role, you will design and develop custom systems for diverse applications, focusing on LabVIEW programming and hardware configuration for Automated...SeniorFull time$62.04 - $93.06 per hour
Qualcomm is seeking a PCB Designer in San Diego to create high-speed PCB layouts for advanced server and compute systems. You will collaborate with electrical and mechanical teams, ensuring designs meet manufacturing standards. Applicants should have over 5 years of experience...Senior$71.25k - $187k
Lilly is looking for an associate-level scientist in the Protein Engineering group at our Biotechnology Center in San Diego. The role involves engineering and optimizing therapeutic proteins, particularly antibodies, collaborating across multiple teams. Ideal candidates...Senior$120.3k - $210.1k
A leading technology company in California is looking for a Signal Integrity Engineer specializing in high-speed serial interfaces. You will work on developing SOCs, ensuring signal and power integrity through simulations and optimizations. The role requires at least a...Senior$129.4k - $194k
...leaders, and world changing projects, you will do more and become more than you ever thought possible. We're seeking a Senior Compute Hardware Engineer to help design next-generation DNA sequencers. You'll own subsystem-level hardware design across compute, memory, I/O,...SeniorWork experience placementLocal areaRemote work$122.5k - $183.7k
Qualcomm is seeking a Cellular Technologies Software Engineer in San Diego, California. This role involves designing state-of-the-art cellular technologies and developing software for ORAN Fronthaul control plane real-time packet processing. Ideal candidates will have...Senior- ...development, and regulatory compliance for innovative health products. The ideal candidate should possess expertise in polymer formulation engineering and experience in the medical device sector. A competitive benefits package and growth opportunities are offered in this...Senior
- ...Senior Radiation Effects Engineer Logos Space is a Low Earth Orbit (LEO) satellite system purpose-built to serve the connectivity needs of the commercial enterprise users and government users. We will help fill an important gap in the market, providing resilient, high...SeniorWork experience placementLocal areaWorldwide
- The University of California San Diego is seeking an R&D Engineer 3 to support the Biomolecular Nuclear Magnetic Resonance (NMR) Facility. This position involves managing and maintaining advanced NMR instrumentation, assisting in biomolecular research, and providing training...SeniorFull time
$98.4k - $147.6k
...become more than you ever thought possible. Team & Role The Senior Reliability Engineer within the Strategic Operations team ensures that... ...with optical, mechanical, electrical, automation, and/or fluidics systems. Ability to learn and understand component level failures...SeniorWork experience placementWork at officeLocal area- ...San Diego Supercomputer Center is seeking a Research and Development Engineer 3 to support the Departments of Chemistry and Biochemistry. This role focuses on biomolecular NMR spectroscopy, collaboration with faculty, and managing advanced NMR instrumentation operations...Senior
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Fluidics Engineer. Be the first to apply!
- senior game producer San Diego, CA
- senior manager process engineering San Diego, CA
- senior manufacturing engineer San Diego, CA
- senior manager clinical operations San Diego, CA
- senior optical engineer San Diego, CA
- senior lead project manager San Diego, CA
- senior manager quality engineering San Diego, CA
- senior device engineer San Diego, CA
- senior full stack developer San Diego, CA
- senior manufacturing manager San Diego, CA

