Principal Research Scientist, QTAS & ADME Sciences

Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube. Job Description AbbVie isseekinga highly motivated and experienced scientist to join ourQuantitative, Translation & ADME Sciences(QTAS)team in North Chicago.The ideal candidate will haveastrong background andexpertisein drug metabolizing enzymefunction, drug-drug interaction concepts, quantitative bioanalysis, ability to drivecutting-edgescienceandlead a team of junior scientists. Applicants having experience in anadjacent area, such asdrugpermeability andtransport,receptor pharmacologyandpharmacokineticmodelingisdesirable. In this exciting role, you will be expected toparticipateinimplementinginnovative and quantitative approachesto advancetranslationalADMEusingconventional as well asmorecomplexin vitro models.Working in a laboratory and non-laboratory setting, the position will involve the conductand scientific leadershipof in vitro assays as well asapplying translational modeling conceptstohelpdrive the globalin vitro ADMEstrategy at AbbVie.The candidatewill beexpected toimplement and/or evaluatenew technologiesand approaches to support the mechanistic and translational understanding ofearly and late-stagesmall molecules tofacilitaterapid advancement ofdrug candidates in ourpipeline. In addition, you will have opportunities to contribute to broader areas within DMPK as your experience andexpertisewarrants. Core Responsibilities Evaluating novel in vitro tools and methods, and apply established methods and concepts to enable and improve prediction of human PK and drug-drug interaction potential. Lead, mentor and coach junior staff in established and novel practices in vitro drug metabolism. Liaise with QTAS, discovery biology/pharmacology/chemistry scientists to generate data and knowledge supporting the build-up of translational, mechanistic models. Communicate internally and externally on topics related to in vitro drug metabolism. Keep up to date with emerging literature and science in modeling and in vitro approaches. Externalize research in the form of full-length publications and oral presentations. Qualifications Basic Qualifications BS or equivalent education and extensive, typically 14+ years of experience; MS or equivalent education with typically 12+ years of experience; PhD with typically 6+ years of experience in area or scientific area of discipline. Experience within in vitro ADME experiments and DMPK projects, through academic or industry work. Deep understanding of drug metabolism and ADME principles including enzyme kinetics, IVIVE and DDI risk assessment. Strong and relevant publication record as well as a track record of strategic scientific leadership in the in vitro ADME field. Highly motivated, self-driven and results-oriented person with excellent communication and presentation skills, capable to work both as team player and independent scientific contributor. Passion for generating ideas, learning, solving technical problems and applying new technologies to further scientific goals. Key Leadership Competencies Builds strong relationships with peers and cross-functionally with partners outside of team to enable higher performance. Ability to inspire and lead others in areas of your expertise. Learns fast, grasps the "essence" and can change course quickly where indicated. Raises the bar and is never satisfied with the status quo. Creates a learning environment, open to suggestions and experimentation for improvement. Additional Information The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our long-term incentive programs. Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employer remains in the Company's sole and absolute discretion until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: #J-18808-Ljbffr Allergan