Antibody Engineering Senior Scientist

A leading biotechnology company is growing their Antibody Engineering team and is in search of a talented scientist with extensive knowledge in guided phage display and antibody discovery technology advancement.Key Responsibilities:Establish and progress innovative phage display techniques — including guided selection methods, structure-informed panning, and epitope-driven strategies — broadening platform capabilities beyond traditional campaign execution.Utilize deep mutational scanning and NGS-based repertoire analysis to gain mechanistic understanding, guide library design, and construct predictive models of antibody fitness landscapes.Create novel phage display selection approaches for complex targets like membrane proteins and conformational epitopes.Contribute to intellectual property and innovation in the field through inventorship and impactful publications.Collaborate with structural biology to utilize cryo-EM, crystallography, and molecular dynamics data for informed, structure-guided engineering choices.Incorporate AI/ML and computational tools into phage display workflows, utilizing generative protein design, protein language models, and in silico affinity prediction to expedite lead discovery and optimization.Qualifications:PhD in Molecular Biology or related discipline.Experience in advanced phage display with focus on method and technology development.Strong track record of impactful publications is preferred.Interest in bridging experimental and computational antibody engineering.