Clinical Data Manager

Faeth Therapeutics is a clinical-stage oncology company listed on Nasdaq that recently raised $200M in funding. With a strong scientific foundation and a founding team that includes the discoverer of our target pathway, we are advancing PIKTOR, a multi-node PI3K/AKT/mTOR inhibitor program, toward multiple near-term milestones. We are a small, focused team where every person has direct impact - united by a shared commitment to care deeply, create boldly, and never stop learning.

Faeth Therapeutics is seeking an experienced Clinical Data Manager to support clinical data management activities across two active clinical trials. This individual will play a critical role in ensuring high-quality, reliable clinical data through the design, implementation, and oversight of data management processes. The role requires close collaboration with clinical operations, biostatistics, medical, and external vendors.

Reports to: Chief Medical Officer

Location: Remote (U.S.)

Responsibilities:

• Lead day-to-day data management activities for assigned clinical trials (Phase 2 and Phase 1b)
• Oversee CRO and vendor data management deliverables to ensure timelines, quality, and compliance
• Review and contribute to key study documents, including:
• Data Management Plans (DMPs)
• Case Report Forms (CRFs) / eCRFs
• Edit check specifications
• Data transfer specifications
• Manage database build, UAT, and database lock activities
• Ensure data integrity, consistency, and completeness through ongoing data review and cleaning
• Monitor query generation and resolution timelines
• Perform data review, listings review, and support medical data review activities
• Collaborate with biostatistics on data standards (e.g., CDISC/SDTM) and analysis datasets
• Ensure compliance with GCP, regulatory requirements, and company SOPs
• Support inspection readiness and participate in audits/inspections as needed
• Contribute to process improvements and best practices in data management

Requirements:

• Bachelor's degree in life sciences, computer science, or related field (advanced degree a plus)
• 5-8 years of clinical data management experience in biotech, pharma, or CRO settings
• Experience supporting early- to mid-phase clinical trials (Phase 1-2 required)
• Hands-on experience with EDC systems (e.g., Medidata Rave, Veeva, Oracle InForm)
• Strong understanding of clinical data standards (CDISC, SDTM)
• Experience managing CROs and external vendors
• Familiarity with oncology trials is preferred
• Knowledge of GCP and regulatory requirements
• Strong attention to detail and problem-solving skills
• Excellent communication and cross-functional collaboration skills

Compensation Range: $125,000 - $175,000 (actual compensation may vary based on experience, qualifications and location)

Working at Faeth

Benefits:

• Competitive salary and equity in a well-funded, clinical-stage biotech
• 100% remote work and flexible schedule
• Health, dental, and vision for you and your dependents
• Flexible time off
• Generous parental leave
• Traditional and Roth 401k
• Mission oriented, remote first culture

We are an equal opportunity employer, and we value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

All offers of employment are contingent upon satisfactory completion of a background check and verification of eligibility to work in the United States.