Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Staff Data Engineer

$168k - $230k

Trial Library

Staff Data Engineer

Trial Library is an AI-native research platform with a mission to improve healthcare outcomes by expanding access to precision medicine.

About the Role

We're hiring a Staff Data Engineer to own the pipelines that move patient data through our platform, from EMR systems to the workflows our teams use to identify eligible patients for clinical trials and help them enroll. This is the center of a major architectural shift for us: moving from narrow, human-assisted data pulls to robust, automated integrations that ingest complete patient records. The clean, complete, and trustworthy data you'll manage powers our AI-assisted patient-trial matching. If healthcare data at HIPAA-grade stakes, messy real-world inputs, and pipelines that genuinely change patient outcomes sound like the right problem space, please keep reading.

Our engineering culture values direct communication, strong ownership, and low-ego collaboration. We laugh a lot and use a ton of Slack emojis. We make decisions quickly, give open feedback, and have a strong bias toward action.

How We Build with AI

AI is deeply embedded in how we work, in our product, and in our SDLC. Our embrace of it didn't come from a mandate but from our own desire as engineers to do more, safely. We use it for coding, testing, measuring, and iterating, and we treat it as a genuine competitive advantage. We're looking for someone who shares that instinct: excited to question long-standing processes and think ambitiously about what's possible when you pair strong engineering fundamentals with AI tooling. If you're already building that way, you'll fit right in.

Underneath it all is a modern platform built on AWS (Lambda, Fargate, SQS, RDS, Bedrock) with Pulumi-managed infrastructure. Our backend is primarily TypeScript, and our data layer centers on PostgreSQL and Drizzle. We care about pragmatic architecture, developer velocity, and systems that evolve as fast as our product and AI capabilities do.

Your Responsibilities

You will own the ingestion and transformation pipelines that bring patient records into our platform and shape them into data our matching systems and human experts can trust.

That means designing for reliability in compute-intensive, long-running workflows: the kind of problems where serial processing breaks under load, timeouts become production incidents, and the right architecture (async pipelines, message queues, container-based compute) separates a working feature from a failing one. You'll own data quality end-to-end: schema design, validation, transformation logic, and the monitoring that catches problems before a clinician does.

You'll partner closely with our AI engineers on the data foundations for patient-trial matching and with our product engineers on how ingested data flows into the workflows our users depend on. You'll monitor production, triage issues quickly, and exercise pragmatic judgment by matching technology to business needs.

Your Qualifications

We are looking for a data engineer with 8 or more years of experience, with at least a couple of years operating at staff scope or equivalent impact. Beyond tenure, what matters most is whether you have demonstrated the kind of high-impact ownership this role requires.

  • Strong pipeline engineering: ingestion, transformation, and orchestration of data at meaningful scale, with real attention to data quality and reliability.
  • Deep SQL and PostgreSQL fluency, including schema design and query performance
  • Solid Python and comfort working in a codebase with TypeScript.
  • Deep AWS experience (Lambda, Fargate, SQS, RDS, and the surrounding ecosystem) and the ability to choose the right service for the right job.
  • Proven track record of leveraging AI coding tools creatively and effectively to build production systems.
  • Demonstrated ability to take autonomous ownership, identifying and resolving systemic issues independently.
  • Startup experience, where you have built from scratch at an early-stage company and treated ambiguity as an opportunity rather than an obstacle.
  • Strong systems thinking, encompassing backend architecture, APIs, databases, and scalability under real-world constraints.
  • Clear communication and influence, with the ability to explain trade-offs to both engineers and non-engineers to earn trust through honesty.
  • Healthcare alignment with a genuine interest in improving clinical trial access and health equity; HIPAA experience a strong plus.

Nice to Have Familiarity with IaC tooling (Terraform, Pulumi, etc), clinical or healthcare data standards (EHR/EMR, HL7/FHIR), and API design patterns are all additive. Experience in a regulated industry is a plus.

$168,000 - $230,000 a year Compensation & On-Site Requirement This is a hybrid role based in San Francisco, CA, with a requirement of three days per week in the office; Wednesday, Thursday, and Friday. The salary range for this position is $168,000–$230,000 per year and reflects a good faith estimate of base pay for candidates working in this location. Final compensation will be based on experience, skills, and qualifications.

Vacancy posted 6 hours ago
Similar jobs that could be interesting for youBased on the Staff Data Engineer in San Francisco, CA vacancy
  •  ...About Us Medical data exchange is one of the biggest unsolved problems in US healthcare. If you've spent any real time in the...  ...falling off either side. The role We're looking for a data engineering leader who can own our data platform end-to-end: You've... 
    Suggested
    Work at office
    Remote work
    Work from home
    Relocation
    Flexible hours

    Metriport Inc

    San Francisco, CA
    21 hours ago
  • $165k - $270k

     ...and follow us on LinkedIn for company news, employee stories, and career updates. Job Summary: Drata is looking for a Staff Data Engineer! This person will be a key member of the growing data team, supporting one of the fastest growing B2B SaaS startups to... 
    Suggested
    Flexible hours

    Drata Inc

    San Francisco, CA
    1 day ago
  •  ...Autodesk had design and make. Operate is the phase that tells you what actually happened, and it is ours. We are seeking a Staff Data Engineer to join our growing team. Our data platform spans a wide surface area: infrastructure, CDC streaming, Databricks operations... 
    Suggested

    MaintainX

    San Francisco, CA
    1 day ago
  • $150k - $200k

     ...paced. We're looking for talented, entrepreneurially minded and data-driven people who also have a passion for helping people do...  ...St, San Francisco, CA).  About the Role We're hiring a Staff Data Engineer to build the data foundation for a new discovery-stage team focused... 
    Suggested
    Seasonal work
    H1b
    Work at office
    Immediate start
    Flexible hours

    Taskrabbit

    San Francisco, CA
    a month ago
  •  ...better time to join us. About the role: At Afresh, we’re building data products to define the future of retail grocery analytics....  ...center of those products is our analytics platform, and as a Staff Data Engineer on the Data Science and Analytics team, you’ll be the... 
    Suggested
    Full time
    Live in

    Afresh

    San Francisco, CA
    a month ago
  • $185k - $223k

     ...Staff Data Engineer At Copper, we're reinventing home appliances for an electrified future. Our flagship Charlie range pairs high-performance induction with integrated battery storage to make the switch from fossil fuels a no-brainer. We're a small, fast, collaborative... 
    Full time
    Work at office
    Remote work
    Flexible hours

    Copper

    Berkeley, CA
    3 days ago
  •  ...Senior Cloud Data Engineer In order to make an application, simply read through the following job description and make sure to attach relevant documents. We are seeking an experienced, highly skilled Senior Cloud Data Engineer to support an Investment Operations... 

    Mainz Brady Group

    San Francisco, CA
    3 days ago
  •  ...Seattle, Washington D.C., Raleigh, London, and Amsterdam. Making data-driven decisions is key to Plaid's culture. To support that, we...  ...data. We provide golden datasets and tooling to teams across engineering, product, and business and help them explore our data quickly... 
    Work experience placement
    Local area
    Flexible hours

    Carbon Data Solutions

    San Francisco, CA
    21 hours ago
  •  ...Data ScientistResponsibilities:Designs, develops, and implements Hadoop ecosystem based applications to support International Search Team. Follows approved life cycle methodologies, creates design documents, and performs program coding and testing. Resolves technical... 

    Software Technology Inc

    San Francisco, CA
    3 days ago
  •  ...ecosystem. A critical pillar of this effort is Master Data Management (MDM): the systems that identify, enrich,...  ...hierarchy we interact with. We are seeking talented engineers at the Senior Member of Technical Staff (SMTS) and Lead Member of Technical Staff (LMTS)... 

    Leadout Capital

    San Francisco, CA
    1 day ago
  •  ...deep industry expertise with advanced software, automation, and data-driven decision-making.The RoleMariana Minerals is building the...  ...supply chain from the ground up—and we're looking for a Senior Data Engineer to help make it autonomous.We're not a software company selling... 
    Contract work
    Immediate start
    Shift work

    Mariana Minerals

    San Francisco, CA
    21 hours ago
  • Block Pay InformationBlock takes a market-based approach to pay, and pay may vary depending on your location. U.S. locations are categorized into one of four zones based on a cost of labor index for that geographic area. The successful candidate's starting pay will be ...

    Block | Square

    San Francisco, CA
    2 days ago
  •  ...About the role We're looking for a top-tier Senior Data Engineer to join our tech team and work hand-in-hand with our CTO, Denis Charrier...  ...Niland, an audio search company (acquired by Spotify), then Staff Engineer at Spotify. 15y of software development experience.... 
    Remote work
    Flexible hours

    Linkup Inc

    San Francisco, CA
    21 hours ago
  • $144.77k - $209.11k

     ...Sr. Data Engineer Employment Type: Full-Time, Mid-level Department: Business Intelligence CGS is seeking a passionate and driven Data Engineer to support a rapidly growing Data Analytics and Business Intelligence platform focused on providing solutions that empower... 
    Full time
    Flexible hours

    Contact Government Services, LLC

    San Francisco, CA
    2 days ago
  •  ...Data at Natural is infrastructure. You will build the pipelines and systems that move,...  ...time, with clean guarantees. As a Data Engineer , you will work closest with: Eric Wang...  ...parties. CPO Walt was the youngest staff engineer at Nextdoor and a retired... 

    Natural

    San Francisco, CA
    2 days ago
  • $170k - $200k

     ...View all jobs Data Engineer San Francisco (On-Site) OR Remote Software Engineering In office Full-time About 11x Most of what GTM teams do all day isn't selling. It's monotonous work like research, list-building, follow-ups, and data entry - things that should... 
    Full time
    Work at office
    Remote work
    Flexible hours
    Shift work

    11x

    San Francisco, CA
    3 days ago
  •  ...innovators everywhere to turn their visionary AI projects into reality. ABOUT THE ROLE This is Hyperbolic's first dedicated Data Engineer, and you will build our data infrastructure from 0 to 1. You'll be one half of a two-person data team, working alongside our... 

    Wwshemi

    San Francisco, CA
    1 day ago
  •  ...Lead Data Engineer We are looking for a Lead Data Engineer to build our Data Engineering function. You will collaborate with the data scientist and engineers to design, build, and scale high-leverage data models, foundational datasets and scalable infrastructure that... 
    Full time
    Local area
    Flexible hours

    Data Science Jobs USA

    San Francisco, CA
    2 days ago
  •  ...We have a full-time job opportunity of Data Engineer in San Francisco, California (Hybrid). Location: San Francisco, California (Hybrid, 3 times a week at client’s office in the Bay Area) Responsibilities Design, develop, test, deploy, and maintain scalable Big... 
    Full time
    Work at office

    NexDimension

    San Francisco, CA
    4 days ago
  • $182k - $242k

     ...Founded in 2017, CoreWeave became a publicly traded company (Nasdaq: CRWV) in March 2025. Learn more at What You’ll Do The Data Engineering Team builds and operates the foundational data infrastructure powering analytics, AI, and operational decision-making across... 
    Permanent employment
    Full time
    Temporary work
    Casual work
    Work at office
    Flexible hours

    CoreWeave

    San Francisco, CA
    1 day ago
  •  ...Data Engineering RoleAs our first dedicated data engineering hire, you'll own the full data stack: ingestion, transformation, warehouse architecture, pipeline reliability, and the systems that connect model outputs back to production. You'll work at the intersection of... 

    Triumph

    San Francisco, CA
    2 days ago
  •  ...Data/ETL Engineer (Founding Team)Location: San Francisco Bay AreaType: Full-TimeCompensation: Competitive salary + early-stage equityBacked by 8VC, we're building a world-class team to tackle one of the industry's most critical infrastructure problems.About the RoleWe'... 

    Fabrion

    San Francisco, CA
    2 days ago
  • £75k - £95k per year

     ...Join to apply for the Data Engineer role at Surecall Tech Join to apply for the Data Engineer role at Surecall Tech Get AI-powered advice on this job and more exclusive features. Direct message the job poster from Surecall Tech Entrepreneur & Recruitment... 
    Full time
    Freelance
    Remote work
    Flexible hours

    Surecall Tech

    San Francisco, CA
    9 hours ago
  • $180k - $200k

     ...for decades is now at the epicenter of sustaining the global economy. About the role Mytra is looking for a Senior Data Software Engineer to build the data platform that the rest of our software reads from. Every robot and station puts out about 2 MB/s of telemetry... 
    Hourly pay
    Work at office

    Mytra Robotics

    Brisbane, CA
    4 days ago
  • $150k - $200k

     ...Senior Data EngineerGibson Dunn is a leading global law firm, advising clients on significant transactions and disputes. Our exceptional...  ...of precision and vision.Based in the US, the Senior Data Engineer will be responsible for designing, building, and operating the data... 
    Local area
    Flexible hours

    Gibson Dunn

    San Francisco, CA
    1 day ago
  •  ...Forward Deployed Data EngineerAt Vori, Forward Deployed Data Engineers bridge the gap between customer systems and our modern grocery platform. You'll work closely with onboarding managers to configure Vori for each retailer's unique needs—reducing out-of-stocks, cutting... 
    Local area

    Vori

    San Francisco, CA
    2 days ago
  •  ...Senior Data EngineerForesite Labs is a translational R&D team that derives insights from precision measurement and population-scale...  ...the right data in the right shape at the right time.Uphold high engineering standards and collaborate broadly. Lead code and design reviews... 
    Remote work
    Flexible hours

    Foresite Labs

    San Francisco, CA
    3 days ago
  •  ...Senior Data EngineerAt Rad AI, we're on a mission to transform healthcare with artificial intelligence. Founded by a radiologist, our...  ...we'd love to have you on our team!We are seeking a Senior Data Engineer to join our engineering team. With our rapid client growth and ambitious... 
    Full time
    Work at office
    Remote work
    Flexible hours

    Rad AI

    San Francisco, CA
    8 hours ago
  • $148.5k - $260.1k

     ...duplicating efforts. Job Category Software Engineering Job Details About Salesforce...  ...critical pillar of this effort is Master Data Management (MDM): the systems that identify...  ...engineers at the Senior Member of Technical Staff (SMTS) and Lead Member of Technical Staff... 

    Jobleads-US

    San Francisco, CA
    4 days ago
  • $155.4k - $208.4k

     ...past, present, and future. Disney Entertainment and ESPN Product & Technology is a global organization of engineers, product developers, designers, technologists, data scientists, and more - all working to build and advance the technological backbone for Disney's media... 
    Work experience placement

    Disney Entertainment and ESPN Product & Technology Careers

    San Francisco, CA
    21 hours ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Staff Data Engineer. Be the first to apply!