Staff Data Engineer
$168k - $230kTrial Library
Staff Data Engineer
Trial Library is an AI-native research platform with a mission to improve healthcare outcomes by expanding access to precision medicine.
About the Role
We're hiring a Staff Data Engineer to own the pipelines that move patient data through our platform, from EMR systems to the workflows our teams use to identify eligible patients for clinical trials and help them enroll. This is the center of a major architectural shift for us: moving from narrow, human-assisted data pulls to robust, automated integrations that ingest complete patient records. The clean, complete, and trustworthy data you'll manage powers our AI-assisted patient-trial matching. If healthcare data at HIPAA-grade stakes, messy real-world inputs, and pipelines that genuinely change patient outcomes sound like the right problem space, please keep reading.
Our engineering culture values direct communication, strong ownership, and low-ego collaboration. We laugh a lot and use a ton of Slack emojis. We make decisions quickly, give open feedback, and have a strong bias toward action.
How We Build with AI
AI is deeply embedded in how we work, in our product, and in our SDLC. Our embrace of it didn't come from a mandate but from our own desire as engineers to do more, safely. We use it for coding, testing, measuring, and iterating, and we treat it as a genuine competitive advantage. We're looking for someone who shares that instinct: excited to question long-standing processes and think ambitiously about what's possible when you pair strong engineering fundamentals with AI tooling. If you're already building that way, you'll fit right in.
Underneath it all is a modern platform built on AWS (Lambda, Fargate, SQS, RDS, Bedrock) with Pulumi-managed infrastructure. Our backend is primarily TypeScript, and our data layer centers on PostgreSQL and Drizzle. We care about pragmatic architecture, developer velocity, and systems that evolve as fast as our product and AI capabilities do.
Your Responsibilities
You will own the ingestion and transformation pipelines that bring patient records into our platform and shape them into data our matching systems and human experts can trust.
That means designing for reliability in compute-intensive, long-running workflows: the kind of problems where serial processing breaks under load, timeouts become production incidents, and the right architecture (async pipelines, message queues, container-based compute) separates a working feature from a failing one. You'll own data quality end-to-end: schema design, validation, transformation logic, and the monitoring that catches problems before a clinician does.
You'll partner closely with our AI engineers on the data foundations for patient-trial matching and with our product engineers on how ingested data flows into the workflows our users depend on. You'll monitor production, triage issues quickly, and exercise pragmatic judgment by matching technology to business needs.
Your Qualifications
We are looking for a data engineer with 8 or more years of experience, with at least a couple of years operating at staff scope or equivalent impact. Beyond tenure, what matters most is whether you have demonstrated the kind of high-impact ownership this role requires.
- Strong pipeline engineering: ingestion, transformation, and orchestration of data at meaningful scale, with real attention to data quality and reliability.
- Deep SQL and PostgreSQL fluency, including schema design and query performance
- Solid Python and comfort working in a codebase with TypeScript.
- Deep AWS experience (Lambda, Fargate, SQS, RDS, and the surrounding ecosystem) and the ability to choose the right service for the right job.
- Proven track record of leveraging AI coding tools creatively and effectively to build production systems.
- Demonstrated ability to take autonomous ownership, identifying and resolving systemic issues independently.
- Startup experience, where you have built from scratch at an early-stage company and treated ambiguity as an opportunity rather than an obstacle.
- Strong systems thinking, encompassing backend architecture, APIs, databases, and scalability under real-world constraints.
- Clear communication and influence, with the ability to explain trade-offs to both engineers and non-engineers to earn trust through honesty.
- Healthcare alignment with a genuine interest in improving clinical trial access and health equity; HIPAA experience a strong plus.
Nice to Have Familiarity with IaC tooling (Terraform, Pulumi, etc), clinical or healthcare data standards (EHR/EMR, HL7/FHIR), and API design patterns are all additive. Experience in a regulated industry is a plus.
$168,000 - $230,000 a year Compensation & On-Site Requirement This is a hybrid role based in San Francisco, CA, with a requirement of three days per week in the office; Wednesday, Thursday, and Friday. The salary range for this position is $168,000–$230,000 per year and reflects a good faith estimate of base pay for candidates working in this location. Final compensation will be based on experience, skills, and qualifications.
- ...Autodesk had design and make. Operate is the phase that tells you what actually happened, and it is ours. We are seeking a Staff Data Engineer to join our growing team. Our data platform spans a wide surface area: infrastructure, CDC streaming, Databricks operations...Suggested
- ...Data Engineering Leader Metriport is an open-source data intelligence platform that helps healthcare organizations access and exchange patient data in real-time: record retrieval that used to take days now takes seconds, and clinicians walk into every appointment with...SuggestedWork at officeRemote workWork from homeRelocationFlexible hours
$180k - $240k
...Staff Data Engineer San Francisco, California, United States Our healthcare system remains frustratingly analog. When you live in a world of one-tap car rides, instant meal delivery, and unlimited streaming, why do you still have to call to schedule a doctor's appointment...SuggestedLive inFlexible hoursShift work$224k - $264k
...About Checkr Checkr is building the data platform to power safe and fair decisions. Over 140,000 companies and millions of people... ...and is a Y Combinator 2024 Breakthrough Company. As a Staff Data Engineer on the People Data team, you'll help build and evolve the centralized...SuggestedWork at officeLocal areaRemote workRelocationFlexible hours3 days per week$186k - $221.91k
...and Washington, D.C. K.ATS Foundry is Keystone’s engineering center of excellence, embedding data, platform, and forensic expertise into the firm’s most... ...run smoother, and deliver greater impact. About The Staff Data Engineer Role You will lead the design and...Suggested$150k - $200k
...paced. We're looking for talented, entrepreneurially minded and data-driven people who also have a passion for helping people do... ...St, San Francisco, CA). About the Role We're hiring a Staff Data Engineer to build the data foundation for a new discovery-stage team focused...Seasonal workH1bWork at officeImmediate startFlexible hours$227.33k - $312.58k
...Job Description Job Description We’re looking for a Staff ML Data Engineer to join Procore’s AI & Frontier Models organization. In this role, you’ll be responsible for designing and building the data systems that power frontier‑scale machine learning research and...Work at officeLocal areaImmediate start3 days per week$179k - $218k
...alongside a team of experts across energy, manufacturing, data center construction, and cloud services. If you... ...Silicon Reality" must be bridged. We are seeking a Senior Staff Data Center Operations Engineer, GPU Hardware Architecture to be the definitive...Temporary work$185k - $223k
...Staff Data Engineer At Copper, we're reinventing home appliances for an electrified future. Our flagship Charlie range pairs high-performance induction with integrated battery storage to make the switch from fossil fuels a no-brainer. We're a small, fast, collaborative...Full timeWork at officeRemote workFlexible hours- ...meaningful impact on the world? Then keep reading - you've come to the right place. Role Description Form Energy is hiring a Staff Data Engineer to build the data systems behind our deployed energy storage projects, turning real-time field telemetry into reliable,...Full timeImmediate startRelocation package
$214.2k - $252k
...values bind us together and make us one. When one falls, we all fall; when one rises, we all rise. Job Summary: On the Data Engineering team, we transform streams of data into insights that solve real-world Pharmacy Benefits Management (PBM) challenges. We empower...Temporary workWork at officeFlexible hours- ...better time to join us. About the role: At Afresh, we’re building data products to define the future of retail grocery analytics.... ...center of those products is our analytics platform, and as a Staff Data Engineer on the Data Science and Analytics team, you’ll be the...Full timeLive in
$220k - $300k
...ML Data Engineer San Francisco, CA · In Person · Full-Time Vizcom is where design teams at companies like Nike, GM, New Balance, and Hasbro bring ideas from sketch to product. Designers use Vizcom to sketch, render, explore color and materials, work in 3D, and prepare...Full timeFlexible hours- ...Koah Labs in San Francisco is seeking strong engineers to design, build, and maintain the infrastructure that powers our adtech platform... ...the stack—from infrastructure (Terraform, AWS, Cloudflare) to data (PostgreSQL, Kafka, Redis) and core apps (Ruby on Rails, React,...
- ...Senior Data Engineer San Francisco, CA Hybrid About us Metriport is an open-source data intelligence platform that helps healthcare organizations access and exchange patient data in real-time: record retrieval that used to take days now takes seconds, and clinicians...Work at officeRemote workWork from homeRelocationFlexible hours
- ...Garuda Ventures is hiring a Sr Data Engineer to manage petabyte-scale data pipelines that will power Factory OS. The role involves designing data architectures and ensuring data quality across various environments. The ideal candidate should have 5-7 years of data engineering...
$110k - $169k
...hard work and excellence. Job Description The Pricing Data Engineer builds and maintains the data infrastructure and tools that enable... ...Rewards that MWS provides to compensate and recognize our staff professionals for their work. Full time positions are eligible...Full timeWork at office$180k - $250k
...Fluency in San Francisco is hiring a full-time AI Engineer to create LLM-powered features and improve AI output quality. You will build new features end to end, partner with product engineers, and evaluate models. Applicants should have experience in TypeScript or Python...Full time- ...Afresh is hiring a Staff Data Engineer to lead the analytics platform that powers our AI-driven grocery analytics. You will evolve data models, strengthen pipelines, and set data governance for internal and customer analytics. Collaborate with data scientists, product...
- ...platform for fighting financial crime. Our integrated solution unifies data across risk teams to help organizations stop fraud in real time,... .... About the role We are looking for a Senior Data/ML Engineer to own the data and machine learning foundation that Sardine's...Remote workWorldwideHome officeFlexible hours
- ...Lead Data Engineer We are looking for a Lead Data Engineer to build our Data Engineering function. You will collaborate with the data scientist and engineers to design, build, and scale high-leverage data models, foundational datasets and scalable infrastructure that...Full timeLocal areaFlexible hours
$150k - $250k
...Gradient is everything. Torus is building the agentic engineering tool that physical engineering firms use to build infrastructure 10x... ...multiple Fortune 500s and major EPCs on critical infrastructure like data centers and energy installations. Gradient is everything....- ...Salesforce is seeking a Senior Data Engineer to build a trusted data foundation powering decision-making across the organization. You will design and scale data models and pipelines, champion data governance, and provide technical leadership across Product, Data Science...
$2,000 per month
...About Build AI Build AI is the data hyperscaler for Physical AI. We co-design hardware... ...ETL is not this job Strong software engineering. Python and at least one systems language... ...research, and we expect all of our technical staff to contribute to both and work across...Contract workWork at officeRelocation package$200.4k - $300.6k
## Staff, Data PlatformApplylocations: San Francisco, CA, USAtime type: Full timeposted on: Posted Yesterdayjob requisition id: JOBREQ-2616119**The opportunity** Unity is looking for a Staff Engineer, Data Platform to help build and scale the data infrastructure powering...Work at officeWorldwideRelocation package- ...veterans and innovative thinkers. We don't believe culture can be engineered - but when it falls into place, it's a once-in-a-lifetime... ...felt so present. Position Overview We're looking for a data engineer to help us turn raw driving data into the well-structured...Local areaFlexible hours
- ...years. But that only happens when clean, structured scientific data and AI are built into how science gets done. Benchling is the... ...software to modern science. Benchling is building AI & Data Engineering (AIDE), a small, autonomous team within our Security & IT...Work at officeLocal areaFlexible hours3 days per week
$150.4k - $277.6k
...Senior Data Engineer Imagine what you could do here. At Apple, new ideas have a way of becoming great products, services, and customer experiences very quickly. Bring passion and dedication to your job and there's no telling what you can accomplish. We are seeking an...Relocation- ...Sr. Data Engineer Employment Type: Full-Time, Mid-level CGS is seeking a passionate and driven Data Engineer to support a rapidly growing Data Analytics and Business Intelligence platform focused on providing solutions that empower our federal customers with the...Full timeFlexible hours
- ...Data Science & Statistical Computing Position Location: United States (SF local preferred) Contract Duration: 12 months with possibility... ...CI/CD pipelines. Creative thinking for solving complex engineering challenges. Ability to present work both verbally and in...Contract workWork experience placementLocal area
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Staff Data Engineer. Be the first to apply!
- engineering aide San Francisco, CA
- technology administrator San Francisco, CA
- staff security engineer San Francisco, CA
- staff data engineer San Francisco, CA
- senior staff systems engineer San Francisco, CA
- senior staff engineer San Francisco, CA
- staff engineer San Francisco, CA
- assistant engineer San Francisco, CA
- staff design engineer San Francisco, CA
- software engineer staff San Francisco, CA



