Scientist - Small Molecule (SMDD)
ACS
Synthetic Molecule Design and Development (SMDD) is a critical function within Lilly Product Research & Development (PRD) responsible for the development of synthetic drug substances and drug products from the pre-clinical phase through commercialization. Process chemistry is crucial to establishing a robust and sustainable supply chain of the synthetic active ingredients that make up Lilly’s portfolio. Our chemists and engineers develop key technical and business solutions across the portfolio using their expertise to accelerate drug development. SMDD delivers on these responsibilities by recognizing diverse talent and cultures are vital to bring the next generation of medicines to patients. Our team is looking for creative candidates to drive solutions to scientific problems contributing to our synthetic molecule route design and development portfolio. Job Position Overview In the synthesis of pharmaceutical candidate compounds, this role is to develop chemical processes, which minimize the cost of production while maximizing manufacturing capacity. The position requires a high degree of synthetic organic chemistry skill and excellent problem-solving capability. The ability to collaborate with multi-functional teams and effectively communicating the appropriate level of scientific data is important. Responsibilities: Top candidates for this position will be expected to: Contribute to a healthy, supportive work culture and maintain a highly organized laboratory area with a strong focus on all aspects of chemical and occupational safety. Plan and execute laboratory experiments, analyze outcomes, optimize conditions, and document and communicate experimental findings. Preparing various quantities of materials (milligrams to grams) for use by the program/project team customers, and interfacing with other chemists, analysts, and engineers for the successful scale-up of the chemical process. Working knowledge of analytical techniques such as HPLC, GC, and TLC; skilled in purification techniques such as flash chromatography and crystallization. Good spectroscopy skills (the ability to operate and interpret results from NMR and mass spectroscopy, for example) Basic Qualifications: BS/MS is Chemistry, Biochemistry, Chemical Engineering, or closely related organic chemistry STEM degree Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1. Additional Skills/Preferences: Good interpersonal skills and a collaborative mindset; excellent ability to communicate and understand customer expectations Demonstrated self-initiative and appropriate risk-taking Ability to prioritize multiple activities and manage ambiguity An active scientific curiosity and interest for complementary disciplines within the pharmaceutical industry Attention to detail and an ability to diagnose problems Proficiency in ChemDraw, Excel, and other software for managing and viewing data Knowledge of and experience using analytical techniques such as NMR and LC-MS. Additional Information: This is a lab-based role Potential exposure to chemicals, allergens and loud noises Travel: 0 to 10% Position Local: Indianapolis, IN; Lilly Technology Center-North (LTC-N) #J-18808-Ljbffr ACS
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Research Scientist, Synthetic Technologies Job ID REQ-10085647 Aug 18, 2026 USA Summary We are seeking a highly talented and motivated... ...to the discovery, development, and characterization of small molecules to further GDC’s mission to discover innovative medicines. You...- Senior Scientist, Drug Discovery Biochemistry & Biophysics Redwood City, CA Senior Scientist, Drug Discovery Biochemistry & Biophysics... ...Biosciences At Integrated, we arefocused onadvancing small molecule therapeutics for age-related diseases. We have built a first-...Visa sponsorshipShift work
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...or an alternative application process. Scientist II-Analytical, Research & Development (ARD... ...(APIs) for traditional synthetic molecules (including potent) and peptides. Primary... ...in method development and validation for small molecules Active Pharmaceutical Ingredients...Full timeLocal area- ...AbbVie Process Chemistry is seeking a highly motivated Senior Scientist to conduct chemical process research and development,... ...clinical development of potential therapies, which may include small molecules, antibody drug conjugates, peptides, and/or oligonucleotides....Temporary workLocal area
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...Developed and validated a standardized method set (generic gradients, column selections, modifier choices) that covers >=80% of small-molecule samples without per-sample method development Reached fluency in independent operation of the preparative SFC fleet for routine...Work at office$145k - $160k
Scientist II or Senior Scientist,MedicinalChemistry Reports To: Mark Vander Wal,Director of Medicinal Chemistry Employment Type: Full... ...with bRo5 drug design (macrocycles, PROTACs, large, small molecules, etc.) Experience with organic synthesis, including transition...Full timeMonday to Friday$50 - $60 per hour
Scientist Analytical Chemistry - Biologics Contract: Worcester, Massachusetts, US Salary Range: 50.00... ...characterization of those fractions. Biologics/large-molecule experience is strongly preferred. Candidates with only pure small-molecule analytical experience are not...Hourly payContract workTemporary workImmediate startRelocation- ...seeks a Postdoctoral Research Associate I for Dr. Xinglong Wang’s laboratory to advance the discovery and development of novel small-molecule therapeutics for neurodegenerative diseases. The role covers medicinal chemistry, design and synthesis, SAR studies, and lead optimization...
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...and passionate Senior Research Associate/Scientist Ito join the protein purification and... ...functional project teams to troubleshoot molecule-specific challenges and inform candidate... ...scale. Optimize purification process for small-scale and large-scale productions to...Work at officeLocal area$300k - $320k
...AI with hands‑on biological research. We're seeking research scientists with deep medicinal chemistry expertise to join the team.... ...experience designing, synthesizing, purifying, and characterizing small molecules. Above all, you'll close the loop between AI-generated...Contract workWork at officeVisa sponsorshipFlexible hours- Anthropic's Life Sciences team seeks a research scientist with deep medicinal chemistry expertise to join a multi-disciplinary group... ...focuses on designing, synthesizing, purifying, and characterizing small molecules, bridging AI-generated hypotheses with experimental data. You...
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Job Description - RESEARCH SCIENTIST (T238492) RESEARCH SCIENTIST - ( T238492 ) Description Position Summary The University of Alabama... ...Candidates are expected to have prior experience in cell culture and small animal handling. Experience in primary neuronal cell culture...Work experience placementWork at officeShift workDay shift- Research San Francisco or New York · SF preferred Research Scientist You will define the research agenda for models that can launch and... ..., and the market-like evals we are known for. We are hiring a small number of unusually strong technical people early, and this role...
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...on more than 100 clinical trials currently in different phases of the FDA regulated drug approval process. Our expert scientists perform large molecule bioanalysis, assay development, validation, and sample analysis at our GLP, GCP , and CLIA compliant laboratories. Smithers...Local area
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