Cell and Gene Therapy Research Nurse III - Cell Engineering & Therapy

Cell And Gene Therapy Research Nurse III - Cell Engineering & Therapy

The Cell and Gene Therapy Research Nurse III is responsible for providing direct patient care and clinical support for patients enrolled in cell therapy and gene therapy clinical trials. This role requires expertise in managing complex advanced therapeutic modalities including CAR-T cell therapies, other cell therapies, and gene therapies.

Responsibilities include, but are not limited to:

• Conduct informed consent for complex cell and gene therapy protocols.
• Attend and/or perform research visits for cell & gene therapy studies.
• Perform/review required protocol assessments including pre-treatment/infusion evaluations.
• Monitor patients for cytokine release syndrome (CRS), immune effector cell-associated neurotoxicity syndrome (ICANS), and other cell/gene therapy-related adverse events.
• Oversee apheresis procedures and cell collection processes.
• Monitor patient responses during and post-cell/gene therapy administration with intensive safety monitoring.
• Conduct specialized patient education on complex cellular and genetic therapies.
• Manage patient medication reconciliation and prescription renewals.
• Triage acute clinical issues specific to advanced therapy toxicities.

Minimum Qualifications:

• Bachelor of Science in Nursing or completed Accelerated Program in Nursing.
• NYS RN License.
• 4 years of cell therapy, gene therapy, or hematologic malignancy research nursing experience in clinical trials.
• Experience with CAR-T cell therapy, cellular immunotherapies, or gene therapy protocols.
• Knowledge of cytokine release syndrome and neurological toxicity management.
• HIPAA, Good Clinical Practice (GCP), and Conflict of Interest (COI) training certification required upon hire.
• Excellent organizational, analytical, and problem-solving skills with the ability to manage multiple clinical trials.
• Excellent interpersonal and organizational skills for managing complex patient populations.
• BLS or ACLS certification from a nationally recognized organization.
• Proficiency with Microsoft Office applications, including Excel, Word, PowerPoint, Teams, OneDrive, and SharePoint.

Preferred Qualifications:

• OCN/AOCNP, BMTCN, or cellular therapy nursing certification; CCRP/CCRC certification; FACT Immune Effector Cell training.
• Supervisory or leadership experience with clinical research staff.
• Experience supporting cell and gene therapy clinical trials or complex biologics studies.
• Familiarity with Columbia University research and clinical systems.

Other Requirements:

• Medical clearance and participation in the medical surveillance program.
• Direct patient contact and/or interaction with human research subjects.
• Use of N-95 respirator as needed.
• Potential exposure to bloodborne pathogens.
• Successful completion of all required compliance and systems training.

Equal Opportunity Employer / Disability / Veteran

Columbia University is committed to the hiring of qualified local residents.