Principal Scientist Chemistry, Small Molecule Process Development and Manufacturing

About This Role We are seeking a highly motivated and creative Chemist to join our Small Molecule Chemical Development team. This position provides an exciting opportunity to lead and mentor scientific and engineering teams in the development of robust processes for the synthesis of a wide range of Small Molecules across various modalities. This Principal Scientist, Chemistry position provides experiences in early phase to late phase drug development and exposure to the design and development of manufacturing processes for clinical and commercial therapeutics. Who We Are We are a team of organic chemists and chemical engineers engaged in the design of innovative processes which supply new medicines to patients. We focus on developing safe, economical, sustainable, cost-effective, and robust processes to support clinical trials and the launch of new medicines across various drug modalities. We are driven by first principles science, data-driven decision-making, and collaborative teamwork. What You’ll Do Lead collaborative development for manufacturing teams to design and conduct laboratory experiments to optimize and characterize the processes of Biogen assets, with an emphasis on improvement in process understanding, robustness, and productivity Design and lead experimental planning to advance the Biogen portfolio. You will be responsible for leading project teams towards the implementation of safe, efficient and robust chemical processes of Biogen drug candidates Responsible for mentoring less experienced staff by promoting the use of key laboratory instrumentation Develop the fundamental process knowledge needed to support the transition of chemical and biochemical processes from laboratory scale to manufacturing partners Collaborate with our Process Chemistry, Analytical Chemistry, Solid Form, Oligo, and Separations colleagues to develop the knowledge and controls needed for the supply of clinical materials and characterization of the process to support regulatory filings Communicate project team research results effectively in team meetings, including engagement in CMC activities including authoring CMC section of INDs Interact with Contract Research and Manufacturing Organizations as project needs evolve, which may include travel Initiate innovative research projects to improve fundamental understanding and control of Biogen processes Expand on your external presence professionally representing Biogen externally in consortia and conferences Engage, mentor, and prepare our future leaders Who You Are You have a passion for exploring novel scientific concepts and are eager to contribute to the design and development and execution of cutting-edge technologies in the service of delivering drug candidates for clinical trials. Your vision and dedication drive you to push the boundaries of scientific endeavors, ultimately impacting patient lives. You thrive in a collaborative environment where urgency, accountability, inclusion, and integrity are shared values. Required Qualifications Ph.D. with 8+ years of relevant experience. M.S. with 10+ years of relevant experience in pharmaceutical or biotech settings. BS with 12+ years of relevant experience in pharmaceutical or biotech settings Strong background in the theory and practice of pharmaceutical chemistry, including demonstrated understanding of route scouting, mechanistic experiments, experience with process characterization, familiarity with process safety and tech transfer protocols, and effective problem solving skills Experience with piloting, manufacturing, and isolation of APIs across several modalities is preferred, as well as familiarity with analytical tools and various purification techniques. Experience with CDMO management Strong communication skills and a desire to thrive in a collaborative, team-oriented environment Job Level: Management Additional Information The base compensation range for this role is: $159,000.00-$219,000.00 Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity. Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance. Benefits Medical, Dental, Vision, & Life insurances Fitness & Wellness programs including a fitness reimbursement Short- and Long-Term Disability insurance A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31) Up to 12 company paid holidays + 3 paid days off for Personal Significance 80 hours of sick time per calendar year Paid Maternity and Parental Leave benefit 401(k) program participation with company matched contributions Employee stock purchase plan Tuition reimbursement of up to $10,000 per calendar year Employee Resource Groups participation Why Biogen? We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives. At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about Biogen. All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States. #J-18808-Ljbffr Biogen