Head of Molecular Dynamics for RNA Therapeutics
Lilly
Lilly’s RNA Therapeutics is seeking a computational biophysicist in South San Francisco to build atomic-resolution models of how chemical modifications influence Ago2 loading and catalytic activity. You’ll develop MD and free-energy models from cryo-EM and biophysical data to guide medicinal chemistry decisions across siRNA programs. You will lead hands-on simulations as an individual contributor and, in the near term, help lead a team of senior computational scientists while collaborating with #J-18808-Ljbffr Lilly
- Lilly's RNA Therapeutics team in South San Francisco is seeking a computational biophysicist to build molecular dynamics and free-energy models of Ago2 guide‑strand complexes. You will use cryo‑EM, crystallography and biophysical data to predict how modification patterns...Molecular
$78k - $98k
Company Addition Therapeutics is at the forefront of biotechnology innovation, building the next... ...using our proprietary PRINT (Precise RNA-mediated Insertion of Transgenes) platform... ...For Bachelor's or Master's degree in molecular biology, biochemistry, cell biology, biotechnology...MolecularFull time$168k - $264k
...mechanistic model that tells our chemists what to make next Lilly's RNA Therapeutics organization is hiring a computational biophysicist in... ...be predicted from a modification pattern. You will build molecular dynamics and free-energy models of Ago2 guide-strand complexes from...MolecularFull timeFlexible hours$364.14k
...Vice President and Global Head of AI for Drug Discovery (AIDD) The Vice President... ...learning department focused on designing therapeutics across the entire Roche/Genentech Research... ...modeling to structural biology, molecular design, and lead optimization. Translate...MolecularLocal areaShift work$143.2k - $265.9k
...lab-based, technical leadership position within the Peptide Therapeutics department. In this lab-based leadership role, you will... ...Experienced in using software (Schrödinger, MOE, Maestro) for molecular dynamics, conformational sampling, and AI/ML-driven sequence optimization...MolecularLocal areaRelocation package- ...function to advance our biologics pipeline. You will define molecular requirements, drive platform innovation, and collaborate across... ...Science, and Technical Development to deliver next-generation therapeutics for patients. #J-18808-Ljbffr F. Hoffmann-La Roche AGMolecular
$168.6k - $313k
...This is a technical leadership position within our Peptide Therapeutics department, focused on advancing Peptide Therapeutics. The... ...and optimization, including conformational sampling and molecular dynamics (MD) simulations. Proficiency in structure-based drug design...MolecularLocal areaRelocation package- ...actually operates. Our model independently learned the principles of molecular interactions, opening up drug treatments that were previously... ...‑on wet lab experience You have experience across multiple therapeutic modalities, including peptides You have experience building...Molecular
$100.4k - $186.4k
..., drug discovery, and safety evaluation across a dynamic portfolio, novel modalities, and emerging therapeutic areas.In this lab-based role, you will provide scientific... ..., confocal and high-content imaging, molecular profiling, and functional readouts.Support the development...MolecularLocal area$100.4k - $186.4k
...translational research to study the molecular pathways driving disease.... ...As an integral member of our dynamic team, you will:Contribute to... ...of MS disease biomarkers and therapeutic targets by integrating human... ..., including single-cell RNA-seq, CITE-seq, bulk RNA-seq,...MolecularFull timeLocal areaRelocation package$103.4k - $192k
...disease and validation of new targets for therapeutic intervention. The department of Animal... ...degree, or equivalent, in genetics and/or molecular biology, with relevant postdoctoral... ...including CRISPR, NGS-based technologies (RNA-seq, ChIP-seq, scRNA-Seq, Long-Read sequencing...MolecularFull timeLocal areaRelocation package$177k - $235k
...models. We are looking for a deep expert in therapeutic antibody development who is eager to... ....Position Requirements:Ph.D. in molecular biology, biochemistry, biophysics, computational... ...structural modeling using molecular dynamics or other physics-based simulation (e.g....Molecular$103.4k - $192k
...enable targeted delivery of nucleic acid therapeutics (such as siRNAs and ASOs). Working in... ...target gene modulation.Apply genetic and molecular perturbation tools, including CRISPR and... ...spatial transcriptomics, or single-cell RNA sequencing for target receptor discovery...MolecularLocal areaRelocation package$100.4k - $186.4k
...strategies to study disease pathways, confirm a therapeutic's mechanism of action, and improve... ...translational research to study the molecular and cellular pathways driving disease to... ...environment.As an integral member of our dynamic team, you will:Establish and conduct experiments...MolecularLocal areaRelocation package$160k - $180k
...and optimization, a deep understanding of molecular biology, and a passion for transforming... ...for library preparation (WGS, enrichment, RNA-Seq, methylation, etc.). Proficiency in... ...the US and Israel - a testament to our dynamic, inclusive, and inspiring workplace where...MolecularWork at officeRemote workFlexible hours- ...experience in Cell Biology Cancer Biology Molecular Biology or a related field (final level... ...with gene editing such as CRISPR and RNA interference Experience with targeted... ...to diverse points of view About Nurix Therapeutics Nurix Therapeutics is a clinical stage...MolecularContract workTemporary work
- ...Head of Dynamics 365 About the Company Established API contract development and manufacturing organization in a regulated GxP environment Industry Pharmaceuticals Type Privately Held About the Role The Company is seeking an IT Head of Dynamics 3...Contract work
$62 - $67 per hour
...prior experience in genetic medicine, CAR-T cell therapy, or RNA therapeutics is a strong plus. Basic knowledge of nucleic acid characterization (e.g., gel electrophoresis, qPCR), familiarity with molecular biology techniques, including cloning (e.g., Gibson assembly,...MolecularHourly payPermanent employmentContract workLocal area$90k - $128k
...Description Job Description About Dualitas Therapeutics At Dualitas Therapeutics, we are... ...is highly preferred. Experience in molecular biology techniques and cell engineering... ...independently and collaboratively in a dynamic, highly cross-functional team...Molecular$45 - $50 per hour
About Allogene Allogene Therapeutics, with headquarters in South San Francisco, is a clinical... ...levels of responsibility, to join a dynamic team responsible for successful development... ...or master’s degree in immunology, molecular biology or related field is required (or...MolecularHourly payContract workLocal area$87k - $91.26k
...extraction, qPCR, RT-qPCR, and related molecular assays Collaborating with senior research... ...with desire to work in a fast-paced, dynamic environment ~ Familiarity with Microsoft... ...company with cutting-edge therapeutic candidates capable of improving the lives...Molecular$155k - $200k
...diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative... ...Principal Scientist with deep expertise in molecular biology and translational biomarker... ...IND, TGA, CTD format) Experience in LNP-RNA biodistribution and PD assay development...Molecular$80k - $120k
...broad-spectrum vaccines and therapeutics targeting mutation-diverse pathogens... ...viral stocks, and supporting molecular cloning efforts in the... ...Qualifications: Familiarity with RNA viruses and mRNA-based... ...therapeutics. Collaborative and dynamic team culture. Professional...Molecular- ...innovative projects. This is a fantastic opportunity to engage in high-throughput workflows and collaborate with a talented team in a dynamic environment. If you have a passion for science and a desire to drive impactful research, this position is perfect for you. #J-18808...Molecular
$28 - $32 per hour
...seeking an Organic Chemist to join their dynamic team. If you're passionate about advancing... ...surfactant synthesis processes Apply molecular biology techniques to support projects in... ...protein expression, gene cloning, and DNA/RNA manipulation Collaborate with cross-functional...MolecularFull timeContract work$80k - $100k
...up new opportunities across oncology and therapeutic development. Position Overview We are... ...(B.S./B.A.) or Master’s (MS) degree in Molecular Biology, Cell Biology, Biochemistry or related... ...needs. Our Core Values: We are a dynamic and diverse team that lives by the culture...MolecularLocal area- ...and machine learning based methods for molecular design within Genentech's Research and... ...relationships with small molecule and protein therapeutic development efforts across the gRED... ...modeling methods (e.g., molecular dynamics) and cheminformatics toolkits (e.g., rdkit...Molecular
- ...thrives on increasing levels of responsibility, to join a new and dynamic team responsible for successful development and... ...appropriate.QualificationsBSc/ MSc or PhD degree in Immunology/ Molecular Biology with 5+ years of experience in biotech/ biopharma industry...MolecularImmediate start
$50 - $60 per hour
...to advance the discovery of novel cancer therapeutics. The final title will be based on your... ...degree in cancer biology, cell biology, molecular biology, or a related field. 2+ years of... ...experience with cell viability assays, RNA interference (siRNA/shRNA), small molecule...MolecularHourly payContract workFlexible hours$75 - $85 per hour
...types, such as WGS/WES/panel-seq, bulk RNA-seq, single-cell RNAseq and spatial transcriptomics... ...understanding of disease biology and molecular/cellular mechanisms in immunology. •... ...teams to pinpoint potential therapeutic targets. • Contribute to accurately represent...MolecularFor contractorsRemote work
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