Senior Manager, Facilities

About SpyGlass Pharma:

At SpyGlass Pharma (NASDAQ: SGP), we are focused on improving and preserving the vision of patients suffering from chronic eye conditions, while minimizing the impact on their daily lives. We aim to achieve this by developing cutting-edge long-term drug delivery products to address common causes of blindness and getting these products to the patients that need them.

We have built a highly collaborative team with deep expertise across ophthalmology, drug delivery, pharmaceuticals, and medical devices. Our scientists, engineers, and clinical leaders bring decades of experience developing and commercializing breakthrough technologies, united by a shared commitment to patients and our guiding principle: "We create for patients." That mindset shapes how we build our products, our teams, and our culture.

Backed by strong clinical progress, significant funding, and a growing organization, SpyGlass Pharma is entering an exciting stage of growth as we advance our lead program, the SpyGlass BIM-IOL, through Phase 3 clinical development.

Summary:

The Senior Manager, Facilities will be responsible for the full scope of site operations at our headquarters. The successful candidate will be a hands-on, self-directed leader capable of overseeing day-to-day functionality of a multi-use site comprising corporate offices, analytical laboratories, R&D drug product manufacturing, and related spaces. The role encompasses site safety leadership, equipment management, and direct coordination of external contractors including cleaning, maintenance, and specialty service vendors. As the company's sole dedicated facilities resource, this individual will build programs and processes from the ground up, partnering closely with R&D, Quality, and Operations leadership to ensure a safe, compliant, and fully operational environment that supports our clinical-stage pipeline.

Essential Duties & Responsibilities:

• Oversee all day-to-day site operations, ensuring spaces are safe, functional, and compliant.
• Provide leadership for and continuously improve the company's Environment, Health & Safety (EHS) program, serving as Safety Officer and ensuring compliance with OSHA, Cal/OSHA, EPA, and all applicable regulations.
• Develop and deliver site safety training, maintain chemical hygiene and emergency action plans, and oversee hazardous materials handling and disposal.
• Manage a comprehensive preventive maintenance program, including equipment inventory, calibration tracking, and coordination of scheduled service for all lab and manufacturing instrumentation, in accordance with SpyGlass procedures.
• Support equipment qualification activities (IQ/OQ/PQ) in collaboration with Quality Assurance.
• Identify, onboard, and manage external contractors-including cleaning, HVAC, electrical, plumbing, and specialty lab service vendors-ensuring quality, safety, and compliance on-site.
• Negotiate scopes of work and service agreements; oversee contractor performance and approve invoices within delegated authority.
• Partner with R&D, Quality, and Regulatory Affairs to maintain facilities documentation and support any inspections and partner audits.
• Manage the facilities budget, support capital expenditure planning, and contribute to future site expansion and buildout activities.
• Serve as primary liaison with building management and landlord for facility matters and site improvements.

Qualifications Required For Position:

• Bachelor's degree in scientific discipline or equivalent experience.
• Bachelor's degree in Facilities Management, Engineering, Life Sciences, Environmental Health & Safety, or a related field preferred; professional certification (e.g., CFM, CHMM) a plus.
• 8+ years of progressive facilities management experience in a pharmaceutical, biotech, or life sciences environment, with direct exposure to laboratory and/or GMP manufacturing spaces.
• Demonstrated experience building or significantly developing a facilities or EHS function, ideally in a startup or growth-stage company.
• Working knowledge of GMP regulations (21 CFR Parts 210/211), laboratory safety standards (OSHA, Cal/OSHA), chemical hygiene requirements, and hazardous waste regulations.
• Hands-on, self-directed operator comfortable managing vendors and contractors independently, with strong organizational and communication skills.
• Proficiency with equipment tracking systems and standard office productivity tools.

Why SpyGlass Pharma?

• We are offering a range of $130,000 - $150,000, based on experience and qualifications, along with an Annual Bonus opportunity.
• Share in our success with stock options, giving you a stake in the company's future.
• Comprehensive health, dental, and vision insurance plans to keep you and your family healthy and happy, with a variety of plan and coverage options.
• Generous paid time off, including holidays, vacation days, and personal leave.

SpyGlass Pharma is an Equal Opportunity Employer and participates in E-Verify. SpyGlass Pharma takes pride in maintaining a diverse environment and our policies are not to discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity, marital or veteran status, disability, or any other legally protected status.


SpyGlass Pharma is also committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an email to View email address on click.appcast.io and let us know the nature of your request and your contact information.