Scientist, In Vivo Pharmacology, Inflammation Research

Career Category Scientific Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas – Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity‑related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives. Our award‑winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Scientist, In Vivo Pharmacology, Inflammation Research What you will do Let’s do this. Let’s change the world. In this vital role you will work in a highly dynamic in vivo pharmacology team executing in vivo preclinical disease models and in vitro assays in the vivarium and lab supporting pipeline programs, managing interactions and presentation of results with project teams and collaborators. Key Responsibilities: Perform hands‑on in vivo work primarily mice, possibly rats and run concurrent studies Design experiments and execute studies, working alongside senior scientists and associate scientists Generate high‑quality experimental data and ensure studies are organized and prepared Supervise/coordinate associate scientists tasks/time as needed for study execution. Analyze and communicate results to project teams and the broader department Understand the biology of supported projects and contribute to project progression Participate in occasional weekend/evening dosing rotations as required. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The Scientist we seek is a driven, pro‑active, independent, and enthusiastic scientist who wants to contribute to cutting edge science and serve patients in a highly productive team environment, with these qualifications. Basic Qualifications Doctorate degree OR Master’s degree and 2 years of Immunology or related experience OR Bachelor’s degree and 4 years of Immunology or related experience Preferred Qualifications PhD degree and post‑doctoral training (or drug discovery experience) in the fields of Immunology, inflammation autoimmune disease, or related disciplines. Strong understanding of Immunology and Inflammation biology and principles. Willingness and curiosity to learn and explore new areas of research. Experience executing in vivo preclinical respiratory disease models, including asthma (OVA, HDM), COPD (Elastase, smoke extract), Bleomycin fibrosis (i.t., i.d., s.c.), respiratory virus infection (PR8) models preferred. Experience with preclinical inflammatory disease models, including colitis, lupus, RA, PBC important. Significant Experience with lung function measurements (FlexiVent, Plethysmography), imaging (mCT), and inhaled drug delivery preferred. Hands‑on experience with in vivo techniques including dosing route of administration (i.v., i.p., p.o., i.n., i.t., r.o., i.d., s.c.), bleeds (r.o., cheek, tail), necropsy (organ collection (intestine/colon, lung, lymphnodes, spleen, liver, kidney, skin), cardiac bleed, lung BAL collection). Hands‑on experience in cellular, biochemical, histological, and molecular biology assay techniques (i.e. ELISA, MSD, multi‑color flow cytometry, quantitative RT‑PCR) preferred. Computer literacy, especially proficiency with GraphPad Prism, Excel, PowerPoint and Word. Attention to detail, excellent organizational and communication skills, accurate & timely record‑keeping and data analysis are essential. Demonstrated track record of independent critical thinking and scientific achievement. Demonstrated experience in and understanding of pharmacology with application using in vivo models of inflammation/Immunology. Experience working on project teams leading in vivo contributions. Ability to work in an a flexible team‑oriented environment. Weekend and evening work may be required. What you can expect from us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well‑being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan Stock‑based long‑term incentives Award‑winning time‑off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. Salary Range

124,301.00 USD - 150,872.00 USD

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. #J-18808-Ljbffr Dormont Manufacturing Co