Global Development Lead, Internal Medicine (MD, Sr. Director)

Global Development Lead, Internal Medicine (MD, Sr. Director) United States - Washington – Bothell United States - New York - Pearl River United States - New York - New York City United States - Pennsylvania - Collegeville United States - Massachusetts - Cambridge We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place. To fully realize Pfizer’s purpose – Breakthroughs that change patients’ lives – we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals. Pfizer Research & Development serves as the beating heart of Pfizer's trailblazing product pipeline, the essence of our mission to bring life‑changing medicines to the world. Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Role Summary Overview: The Global Development Lead (GDL) represents Clinical on the Global Medicine Team and is the sole clinical point of accountability for clinical development for assigned asset(s) in Internal Medicine. The GDL leads the cross‑functional Clinical Development Team—clinical, clinical pharmacology, statistics, safety, commercial, patient access, and operations colleagues—in the design, execution, and interpretation of studies supporting worldwide regulatory submissions. The GDL is accountable for creating, gaining endorsement for, and maintaining the Clinical Development Plan and associated protocol design documents. The GDL partners with other clinical, clinical operations, and external companies in the lifecycle of all studies for the assigned asset(s) and is a subject‑matter expert in both therapeutic area and clinical drug development. Additional responsibilities include leadership within the Obesity portfolio and support for late‑stage assets, specialized monitoring, and regulatory submission activities. Responsibilities Partner effectively with the Medicine Team Lead to negotiate tradeoffs, milestones, and ensure delivery of the clinical program in line with agreed timelines and budget. Develop and execute a comprehensive clinical development plan to secure approval and reimbursement globally (including China and Japan), including creating pediatric investigation and study plans and protocols in collaboration with trial clinicians. Provide product‑program specific input for target product profiles. Bring innovative thinking and bold decision‑making across clinical development programs and studies. Develop clinical development enabling strategies, including digital/innovation and patient engagement approaches. Partner with trial clinicians on governance reviews (incl. Sci/Ops) for assigned studies; provide strategy input and insights. Provide specialized medical monitoring support for trial teams, if required. Collaborate with statistics and programming on the trial‑level statistical analysis plan, tables, listings, figures, and database release. Support appropriate interpretation and communication of clinical trial data. Review and approve submission‑level safety narrative plans. Support product label development and maintenance. Engage external stakeholders (e.g., advisory boards, steering committees, DMC, adjudication committees, patients and patient advocates) to generate strategic insight for clinical development and PDD. Provide regulatory submission support (DSUR, PBRER) and product defense. Ensure compliance with internal SOPs and external regulatory standards. Review IIR proposals.

BASIC QUALIFICATIONS

Education: MD or DO. Experience: 8+ years of relevant experience and track record of success in academia and/or the biopharmaceutical industry in clinical research and development. Cardiologist (strongly preferred) with cardiovascular outcome trials or large complex, global development programs. Extensive knowledge of clinical development, global and regional regulation, ICH/GCP, adverse event management. Demonstrated clinical/medical, administrative, and project management capabilities, and effective verbal and written communication skills. Experience managing and training large teams in clinical development. Experience designing and launching large teams preferred. Competency Requirements Medical / Scientific credibility and excellence; track record in pharmaceutical development and understanding of disease areas. Management experience; ability to work in a complex matrixed environment and influence cross‑functional teams. Leadership; persuasive and effective leader of staff. Influencing; ability to manage and motivate internal teams on clinical trials. Conflict Management; mentor/coach, resolve conflicts effectively, and take responsibility for decisions. Team Building; foster open dialogue, create strong morale, and promote belonging. Accountability; personal responsibility for results and pushing self and others to exceed goals. Change Agility; demonstrate perspective and poise amid organizational change. Broad leadership experience; ability to influence, collaborate, develop, coach, and guide colleagues for business impact. NON-STANDARD WORK SCHEDULE, TRAVEL, OR ENVIRONMENT REQUIREMENTS Up to 30% travel may be required. Relocation support available. Work location assignment: This is a hybrid role requiring you to live within commuting distance and work on‑site an average of 2.5 days per week. Salary and Compensation The annual base salary for this position ranges from $274,500.00 to $457,500.00.* The position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 25.0% of the base salary and eligibility to participate in our share‑based long‑term incentive program. The annual base salary ranges for Tampa, FL are $228,700.00 to $381,100.00. Benefits offered include a 401(k) plan with Pfizer matching contributions, a Pfizer retirement savings contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits (medical, prescription drug, dental, and vision coverage). Learn more at Pfizer Candidate Site – U.S. Benefits (uscandidates.mypfizerbenefits.com). Benefits Competitive salary Performance bonus Long‑term incentive program Retirement and 401(k) match Health, dental, vision coverage Paid vacation, holidays & personal days Paid caregiver/parental and medical leave Employee assistance program EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability, or veteran status. Pfizer complies with all applicable laws governing nondiscrimination in employment and work authorization. Pfizer is an E‑Verify employer. This position requires permanent work authorization in the United States. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. If you are a licensed physician who incurs recruiting expenses during interviewing, those expenses may be reported to the government. Please contact your Talent Acquisition representative if you have questions regarding this matter. Additional Information Candidates must be authorized to be employed in the U.S. by any employer. U.S. work visa sponsorship (such as TN, O‑1, H‑1B, etc.) is not available for this role now or in the future. #J-18808-Ljbffr Pfizer, S.A. de C.V