Senior Scientist I- Translational Medicine- PKS, ADME
$89.6k - $166.4kScorpion Therapeutics
Key Responsibilities Plan, execute, and report ADME assays (e.g., metabolic stability and permeability) to support PK strategies. Interpret in vitro ADME data and translate findings for early discovery, compound optimization, and selection. Contribute to novel ADME methodologies and expand assay capabilities. Advance automation strategies (liquid handling, assay miniaturization, assay multiplexing) to increase capacity, standardize execution, and reduce manual effort. Execute and/or contribute to fully automated, end-to-end ADME workflows integrated with AI-enabled analytics. Develop methods for small and large molecule bio-analysis using LCMS-MS, HRMS, and ICP-MS. Troubleshoot lab instrumentation and automation platforms. Manage study timelines, objectives, and budgets; ensure accurate progress tracking in company tools. Communicate data, strategy, and results to project teams. Contribute to internal ADME study reports and regulatory documents (IND, IMPD, NDA, etc.). Participate in cross-departmental teams and initiatives. Complete required organizational trainings and requirements; adhere to SOP, quality, and HSE guidelines. Essential Requirements BSc or MSc in drug metabolism/pharmacokinetics or related field; BSc: 7+ years; MSc: 4+ years ADME/DMPK. Experience in discovery/development labs or CRO/Pharma/Biotech highly desirable. Metabolic stability and permeability assay experience highly preferable; cell culture a plus. Laboratory automation integrated with AI-enabled analytics highly desirable. Knowledge of related disciplines (bioanalytical, toxicology, biomarker). Strong organizational/project skills and critical thinking/problem-solving. Ability to work in a cross-functional, matrixed environment. Fluent oral and written English. Compensation/Benefits Salary expected range: $89,600–$166,400/year; performance-based cash incentive; potential annual equity awards; comprehensive benefits and time off for eligible employees. #J-18808-Ljbffr Scorpion Therapeutics
$89.6k - $166.4k
...Location: Cambridge Internal Title: Senior Scientist I Support discovery and development... ...development, and execution of in-vitro ADME assays, while building next generation... ...strategies. Interpret in vitro ADME data and translate findings to support early discovery,...Senior$286.9k
...Senior Principal Scientist (Senior Medical Director) Translational Medicine, Immunology Translational Medicine in our Research & Development Division is responsible for planning and managing an important inflection point in the drug development process, working closely...SeniorFor contractorsWork at officeRemote workWorldwideMonday to FridayMonday to ThursdayShift work3 days per weekMerck & Co. Inc
Boston, MA3 days ago$148.5k - $214.5k
Job Title: Senior Principal Scientist I, Translational Disease Biology Location: Cambridge, MA About the job As Senior Principal Scientist I within the... ...TDSB, Therapeutic Areas, and the Translational Medicines Unit. You will lead cross‑functional projects driving...Senior- Sanofi in Cambridge, MA is seeking a Senior Principal Scientist I in Translational Disease Biology. You will lead cross-functional projects spanning TDSB... ..., inform development decisions, and apply precision medicine strategies for measurable impact. #J-18808-Ljbffr SanofiSenior
- Bristol Myers Squibb is looking for an experienced Immunologist to join their Translational Research team in Cambridge, MA. This pivotal role involves developing biomarker assays and collaborating with project teams to advance oncology programs. The successful candidate...Senior
- ...A global biopharmaceutical company is seeking a Senior Principal Scientist to lead drug discovery efforts in muscle biology. The position emphasizes... ...junior scientists, managing projects, and advancing translational research. Candidates should possess a PhD with 15+ years...SeniorWork at officeRemote work
UCB
Cambridge, MA3 days ago $128.6k - $210k
...Regeneron’s Precision Medicine Quantitative Biomarker team (PMQBS) is seeking a Principal Scientist with a blend of deep biomarker and translational‑science expertise coupled with advanced computational... ...Medicine Strategy Leads and senior stakeholders. Translate program...Regeneron Pharmaceuticals
Cambridge, MA2 days ago$286.9k
...Job Description Senior Principal Scientist (Senior Medical Director) Translational Medicine, Immunology Translational Medicine in our Research & Development Division is responsible for planning and managing an important inflection point in the drug development process...SeniorFull timeFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work- Sanofi is seeking a Senior Principal Scientist I in Cambridge, MA to lead projects in Translational Disease Biology. This role demands deep disease expertise and aims to... ...edge research to develop impactful precision medicine strategies. Candidates should possess a PhD,...Senior
- Eacademy Sanofi is looking for a Senior Principal Scientist I, Translational Disease Biology to lead cross-functional projects in Cambridge, Massachusetts... ...identification and the development of precision medicine strategies. The ideal candidate holds a PhD and has substantial...Senior
$260.3k - $409.7k
...Job Overview Translational Medicine is responsible for early clinical development of novel therapeutics, working in close collaboration with... ...on Immunology within the Research Division. The Principal Scientist (Medical Director level) must have a strong background in basic...For contractorsWork at officeRemote workWorldwideMonday to Friday3 days per weekMerck & Co. Inc
Boston, MA2 days ago- Bristol-Myers Squibb in Cambridge, MA is seeking a Senior Scientist in Cancer Immunology to join their Translational Research team. The ideal candidate will be highly motivated with a Ph.D. and extensive experience in oncology and immunology. This role includes designing...Senior
- Job Title: Senior Principal Scientist I - Functional Biomarkers Location: Cambridge, MA About the Job Functional group leader in the US... ...Laboratory Sciences group, a global department within the Translational Medicine Unit of Sanofi. The individual in this position will...SeniorLocal area
- Monte Rosa Therapeutics seeks an experienced DMPK and ADME Scientist to lead drug development efforts, ensuring suitable clinical candidates... ...effectively. The role demands strong collaboration with medicinal chemistry and clinical teams to drive projects through regulatory...Senior
$148.5k - $214.5k
...Senior Clinical Scientist – Cambridge, MA Job Overview The Senior Clinical Scientist is a key member of the Rheumatology/Transplant Clinical... ..., regulatory affairs, clinical operations, translational medicine; support project team members, project management, medical...SeniorSanofi
Cambridge, MA2 days ago- ...Rosa Therapeutics Inc. in Boston is seeking an experienced DMPK and ADME Scientist to lead efforts in the discovery and development of drug pipelines. The role involves close collaboration with medicinal chemistry teams and managing external collaborations, thus critical...Senior
- ...Job Title : Senior Clinical Scientist Location : Cambridge, MA About the job: The Senior Clinical... ...innovative pipeline – enables us to invent medicines and vaccines that treat and protect... ...affairs, clinical operations, and translational medicine Support project team...Senior
Eacademy Sanofi
Cambridge, MA2 days ago $149k - $237k
...Senior Clinical Scientist (Cambridge, MA) Help shape the future of robotic-assisted interventions by bringing clinical insights, physician perspectives... ..., engineers, product managers, and researchers to translate emerging clinical needs into innovative robotic solutions....SeniorFull timeWork at officeWork visaRelocation package3 days per weekPhilips
Cambridge, MA4 days ago- Amgen Inc. (IR) in Massachusetts is looking for a Senior Scientist in Translational Safety & Risk Sciences. You will lead initiatives to develop and integrate data infrastructure and analytics platforms across the organization. Your role will involve collaborating with...SeniorRemote job
- The Council of State and Territorial Epidemiologists is seeking a Senior Clinical Scientist in Cambridge, MA. This role involves leading collaborations with physicians and engineers to translate clinical needs into innovative robotic solutions. You will contribute to clinical...Senior
- Philips North America in Cambridge, MA is seeking a Senior Clinical Scientist to help shape the future of robotic-assisted interventions. You... ...-functional teams, including physicians and engineers, to translate clinical needs into innovative solutions. Ideal candidates...Senior
$98.7k - $183.3k
...Description Summary LI#-Onsite (Lab Based) - Internal Title: Senior Scientist II - Location: Cambridge This role is based in Cambridge... ...is accessible for you. As a Senior Scientist II in our Translational Medicine Drug Disposition Discovery Bioanalytical group, you will...SeniorLocal areaRelocation packageShift work$132k - $258.5k
...is seeking a motivated and innovative (Senior) Scientist, Machine Learning to join our team. In... ...programs in close partnership with medicinal chemistry, while developing rigorous benchmarks... ..., biology, and proteomics teams to translate platform data into actionable models...Senior- ## Senior Scientist, Cancer Immunology Translational ResearchCambridge Crossing - MA - US* Design and develop biomarker, pharmacodynamic, and target engagement... ...1+ year in translational research / translational medicine.* Strong immunology experience, with an emphasis on...SeniorFull timeContract workTemporary work
$132k - $258.5k
...sustainability. COMPANY DESCRIPTION Expedition Medicines is a privately held, early‑stage... ...seeking a motivated and innovative (Senior) Scientist, Machine Learning to join our team. In... ..., biology, and proteomics teams to translate platform data into actionable models for...Senior$142.22k - $172.34k
...experienced Immunologist to join the Translational Research team within the... ..., engaged, and creative scientist that can thrive in a highly... ...solutions and courses of action for senior staff, including... ...translational research/translational medicine. Strong immunology...SeniorFull timeContract workTemporary workSummer workFlexible hours$90 - $100 per hour
...*** Position Summary We are seeking an accomplished Senior Translational Scientist to join our Translational Research team and drive biomarker... ...and scientific advancements in translational medicine, immunology, inflammation, and digital pathology. QualificationsRequired...SeniorContract workTemporary workActalent
Watertown, MA3 days ago- ...accelerate the development of groundbreaking medicines. We have rapidly established an... ...Position Summary: We are seeking a Senior Scientist, DMPK, to join our R&D group and work with... ...teams, and external audiences. Propose ADME/PK, biodistribution and PK-PD...SeniorFlexible hours
Atavistik Bio
Cambridge, MA6 days ago $119.1k - $187.5k
...with a varied portfolio of prescription medicines, oncology, vaccines and animal health... ...& Development. We are seeking a Senior Scientist to join our Digital Insights team within... ...host cell protein characterization, post-translational modification (PTM) characterization,...SeniorFor contractorsLocal area- ...is to discover and deliver innovative medicines and solutions that solve serious health... ...seeking a highly motivated and talented Scientist with a background in immunology or immuno... ...biology, and cell biology to join the Translational Research team. This individual will...SeniorFull timeLocal area
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Scientist I- Translational Medicine- PKS, ADME. Be the first to apply!
- support scientist Cambridge, MA
- analytical scientist Cambridge, MA
- safety scientist Cambridge, MA
- hplc scientist Cambridge, MA
- drug safety scientist Cambridge, MA
- research scientist - biology Cambridge, MA
- senior principal scientist Cambridge, MA
- water quality scientist Cambridge, MA
- qc scientist Cambridge, MA
- decision scientist Cambridge, MA