Principal Scientist
Flagship Ventures
Flagship Pioneering's Pioneering Intelligence team in Cambridge, MA seeks a Principal Scientist to lead translational modeling and decision science. You will build mechanistic models to reduce uncertainty in drug development decisions and provide quantitative insights across programs. You will shape product requirements for AI-enabled translational tools, define context of use, and communicate results to stakeholders with defensible assumptions and transparent uncertainty. #J-18808-Ljbffr Flagship Ventures
$160k - $235k
...Sr. Scientist/Principal Scientist, Translational Research and Clinical Biomarkers (Immunology) Boston, MA Salary Band: $160,000-$235,000 Location: Downtown Boston, MA Position Summary Antares Therapeutics is seeking to add an enthusiastic and highly motivated...Principal- ...development, scale‑up, and technology transfer for small molecule oral dosage forms across all development stages. You will mentor scientists, drive cross‑functional CMC/regulatory activities, and advance enabling formulation strategies to improve portfolio execution and...Principal
- UCB in Cambridge, MA is seeking a Senior Principal Scientist to lead translational biology drug discovery with emphasis on muscle biology. You will shape in vitro and in vivo models and develop cellular and biochemical assays for early programs across multiple neuromuscular...Principal
- ...MassachusettsCompany: Planet Pharma GroupContact: ApplicationsEmail: ****@*****.*** are seeking a highly skilled Scientist to join our Biologics Discovery team and lead antibody discovery efforts. We are looking for someone who thinks carefully about...Principal
- ...Principal Scientist Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and...Principal
$137k - $215.27k
...information I submit in my employment application is true to the best of my knowledge.Job DescriptionAbout the role:The Pharmacovigilance Scientist, Senior Scientist ensures regulatory compliance and safety of Takeda's products by managing large projects, developing innovative...PrincipalMinimum wageLocal area$169.8k - $355.4k
...particular business problems with our assistance and expertise. In this role, you will have an opportunity to work with teams of applied scientists and engineers to deliver high quality computer vision models and services that delights our customers with the confidence that...PrincipalTemporary workFlexible hours$126k - $234k
...In Vivo Scientist This position is located in Cambridge, MA and does not have the ability to be located remotely. Please only apply if this area is accessible to you. NIBR Oncology strives to reimagine medicines for cancer patients through a combination of treatment...PrincipalRemote work- ...discovery, preclinical, clinical, safety, and real-world evidence with scalable data products and governance. You will partner with scientists, knowledge architects, AI engineers, and platform teams to define a future-state data ecosystem and deliver high-quality,...Principal
- Zealand Pharma in Cambridge, MA seeks a Principal Scientist to lead the DMPK/ADME strategy for complex drug modalities and to build discovery platforms and bioanalysis capabilities. You will shape strategy, culture, and technical excellence from the ground up. You will...Principal
$142.5k - $256.5k
..., as a shared discovery resource. This role is intended for a scientist ready to own and evolve a core discovery capability, led by scientific... ...independence, judgment, and ownership consistent with a Principal Scientist role. Here's What You'll Bring to the Table (...PrincipalPermanent employmentWork at officeWork from home- Johnson & Johnson is seeking a Principal Scientist, Animal Genetic Engineering - Antibody Discovery, to design and engineer mouse models for advanced antibody discovery. Based in Cambridge, MA or Spring House, PA, the role integrates mouse genetics, CRISPR, B cell immunology...Principal
$120k - $180k
Predicta Biosciences Inc. is seeking an experienced R&D Scientist to lead assay development spanning flow cytometry and NGS, including single-cell techniques. The role involves designing multi-color panels, optimizing library preparation, and translating research concepts...PrincipalFull timeWork at office$170k - $205k
...,000 Location: Boston, MA Job Summary Antares Therapeutics is seeking an accomplished, technically driven Sr. Scientist II/ Principal Scientist to join our Chemical Biology team. This is a senior individual-contributor role for a proteomics and mass spectrometry...Principal$170k - $200k
...Opportunity to make a significant impact on the development of novel therapeutics Work with a talented and passionate team of scientists Be a part of a cutting-edge company that is revolutionizing drug discovery Psivant Therapeutics, Inc. (d/b/a PsiThera) is...Principal- We are seeking a Senior Principal Scientist to join the US Neuromuscular group based in Cambridge, MA and help drive translational biology drug discovery efforts with an emphasis on muscle biology . This is an opportunity for a scientific leader to advance portfolio projects...PrincipalLocal area
$126.2k - $264.1k
Job Description Independently partners with science, engineering, and product teams to translate business needs into a clear research plan and production-ready solutions. Leads end-to-end applied research: surveying state of the art, preparing high-quality datasets,...PrincipalTemporary workFlexible hoursShift work$115k - $215k
...quantitative proteomics data analysis tools.Domain leadership with cross-functional drug discovery:Highly organized, solutions-oriented scientist with the ability to manage multiple priorities simultaneously while driving innovation in targeted proteomics workflows and...Principal- ...tools, and/or technological capabilities in a given area. About the Role: Synolo Therapeutics is seeking an experienced Principal Scientist to help establish and advance our analytical and biophysical characterization capabilities within the Protein Science team....PrincipalLocal area
- ...with the potential to address significant unmet medical needs. We are seeking an accomplished, creative, and highly collaborative scientist to lead the Cellular Biology function. The ideal candidate will bring deep scientific and technical expertise in bone marrow...Principal
$168k - $252k
Job DescriptionVertex is seeking an accomplished Senior Principal Scientist with proven record of developing, testing and deploying scientific computational methods and agentic AI systems for drug discovery. In this role, you will work across modalities with emphasis on...PrincipalFull timeSummer workRemote workFlexible hours2 days per week3 days per week$146k - $236k
About Pioneering IntelligencePioneering Intelligence builds on Flagship Pioneering’s legacy of founding cutting-edge science and computational ventures, harnessing recent advances in AI, machine learning, and data to accelerate fundamental research and create a portfolio...Principal$148.5k - $214.5k
Job title: Senior Principal Scientist/Principal Scientist, Real-World Evidence & Disease GenomicsLocation: Cambridge, MAAbout the JobJoin Sanofi's Target, Disease and Systems Biology (TDSB) team and become a key contributor to our Disease Genetics and Genomics cluster....PrincipalFull time$215k - $245k
...disease data to identify, credential, and advance new therapeutic opportunities. You will serve as the lead Translational Data Scientist for preclinical Projects, from target identification and credentialing through lead optimization. You will define the computational...PrincipalShift work$168k - $252k
...high-value opportunities across the design-make-test-analyze (DMTA) cycle and translate them into scientifically rigorous AI co-scientists that enhance compound design, knowledge synthesis, data interpretation, hypothesis generation, and decision-making. Although the...PrincipalFull timeSummer workRemote workFlexible hours2 days per week3 days per week- Job Responsibilities • Work with team members to drive forward new gene therapy programs • Perform cell culture and molecular biology experiments and establish new functional assays to measure gene therapy outcomes both in vitro and in vivo. • Establish...PrincipalFull timeH1bVisa sponsorshipWork visa
$179k - $236k
...nonclinical and clinical programs, operating as a hands-on scientific leader. We are looking for an accomplished DMPK and bioanalytical scientist with experience in PK study design, bioanalytical method development, and translational biomarker strategy. This person will...Principal$160k - $190k
...functional meetings and executive forums to support data-driven decision making. Serve as a mentor and technical advisor to junior scientists, fostering scientific rigor and growth within the biology organization. Champion scientific innovation, propose novel assay...PrincipalShift work$188k - $259k
...About This Role Biogen is seeking a Sr. Principal Scientist, Oral Drug Product Development to provide scientific and strategic leadership for the development of small molecule oral drug products. This role leads scientific and engineering efforts supporting formulation...PrincipalFull timeTemporary workLocal area$214.1k - $337k
...Job Description Senior Principal Scientist - Boston, MA Overview We are seeking a Senior Principal Scientist to provide scientific and strategic leadership for mass spectrometry-enabled discovery within the Quantitative Biosciences group in Boston. This role...PrincipalFull timeFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work
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