Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal Scientist, Drug Discovery

$169.7k - $267.2k

Merck Sharp & Dohme

Job DescriptionJoin the Rahway, NJ Animal Health TeamOur Company's Global Animal Health Research & Development (R&D) division is a pioneer in the discovery, development and registration of vaccines and therapeutics for animals.. To strengthen our team, we are looking for a highly skilled and motivated Principal Scientist to join our R&D team.Purpose of the RoleThe Principal Scientist, Drug Discovery in our Research and Development Department will be responsible for identifying new molecular entities and technologies for use in animal health from our Company Laboratories or from external partners such as human pharma or biotech companies as well as academia. The successful candidate will be a key driver to advance novel targets and will lead these research programs from ideation through the early research and proof-of-concept phase up to the development stage. She/he/they will interface with researchers and senior management throughout the organization as well as external partners and operate within a matrix structure to garner resources for the necessary research work (Medicinal and Process Chemistry, in vitro Pharmacology, Pharmacokinetics, Disease Models, Formulation Development, Safety & Toxicology). The position will report directly to the Distinguished Scientist and Global Head, our Company's Research & Development Liaison and Discovery – Non-infectious Diseases.Education:Required: PhD and/or DVM/VMD, with Board certification in pharmacologyRequired Experience:Minimum of 8 years industry or pharmaceutical research experience in drug discovery or preclinical research with a focus on in vivo pharmacologyAdvanced and thorough scientific knowledge in pharmacology, disease mechanisms and related preclinical modelsExpertise in one of the following fields: oncology, diabetes, respiratory & immunology, cardiology, pain & inflammation, or reproduction.Knowledge of regulatory aspects of pharmaceuticals including GLP, GCP and GMPAbility to manage multiple projects, including budgets, contracts, and timelinesAbility to independently plan, recommend and complete research programsExcellent communication and interpersonal skillsEffective creator of executive level presentations and documentsExperience in preparing patent applications in support of patent coverage of research efforts10 % TravelPreferred Experience:Board certification in PharmacologyProject management skills within pharmaceuticalsExperience in developing and managing collaborations with outsource providers, vendors, contractors and academic institutionsExperience in working with business development to identify and license external technology opportunitiesAnimal HealthOur Animal Health Division is a trusted global leader in veterinary medicine, dedicated to preserving and improving health, well-being, and performance of animals and the people who care for them. We are a global team of professionals working together to make a positive difference in animal care and the world’s food supply and have a deep sense of responsibility towards our customers, consumers, animals, society, and our planet.Through our commitment to The Science of Healthier Animals, we offer veterinarians, farmers, pet owners and governments one of the widest ranges of veterinary pharmaceuticals, vaccines and health management solutions and services. We invest in dynamic and comprehensive R&D resources and a modern, global supply chain. We are present in more than 50 countries, while our products are available in some 150 markets.Required Skills: Adaptability, Communication, Detail-Oriented, Ethical Compliance, In Vivo Models, In Vivo Pharmacology, Leading Project Teams, Persuasion, Professional Networking, Science, Social CollaborationPreferred Skills: Current Employees apply HERECurrent Contingent Workers apply HEREUS and Puerto Rico Residents Only:Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:EEOC Know Your RightsEEOC GINA Supplement​We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.Learn more about your rights, including under California, Colorado and other US State ActsThe salary range for this role is$169,700.00 - $267,200.00This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at .You can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance OrdinanceLos Angeles Residents Only:We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring OrdinanceSearch Firm Representatives Please Read CarefullyMerck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.Employee Status: RegularRelocation:DomesticVISA Sponsorship:NoTravel Requirements:10%Flexible Work Arrangements:HybridShift:Not IndicatedValid Driving License:NoHazardous Material(s):N/AJob Posting End Date:09/28/2026*A job posting is effective until 11:59:59PM on the day BEFOREthe listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date. SummaryLocation: USA - New Jersey - RahwayType: Full time Merck Sharp & Dohme

Vacancy posted 1 day ago
Similar jobs that could be interesting for youBased on the Principal Scientist, Drug Discovery in Rahway, NJ vacancy
  • $190.8k - $300.3k

     ...Job Description The Nonclinical Drug Safety (NDS) Therapeutic Area Leader (TAL) is a senior scientific...  ...through close collaboration with Program Coordinators, Discovery Preclinical Leaders, Compound Leaders, and scientists across NDS and/or Preclinical Development, while... 
    Principal
    Full time
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    Rahway, NJ
    22 days ago
  • $173.2k - $272.6k

    Job Description Position Title: Principal Scientist, Early Development Center of Excellence Our company...  ...to medicines, working from the discovery interface through registration stability...  ...device, and manufacturing process. Driving drug product design from the bench top to... 
    Principal
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    RiseMe

    Rahway, NJ
    3 days ago
  • $142.4k - $224.1k

    Job Description Job Description: Associate Principal Scientist, Biomarker Operations Role Summary The Associate Principal Scientist, Biomarker...  ...project management experience. Proven experience in drug discovery and/or clinical research. Demonstrated ability to excel... 
    Principal
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co. Inc

    Rahway, NJ
    3 days ago
  • $190.8k - $300.3k

     ...Research and Development division, quantitative scientists, in partnership with other subject matter...  ...methodologies and tools to enable the discovery, development, regulatory approval, manufacturing, and marketing of medical drugs and vaccines for the benefit of patients... 
    Principal
    Full time
    Contract work
    For contractors
    Work experience placement
    Local area
    Worldwide
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    Rahway, NJ
    4 hours ago
  • $173.2k - $272.6k

     ...Development (SMPR&D) Department in Rahway, New Jersey is seeking a Principal Scientist to expand and deepen our capabilities for data science,...  ...science, and advanced automation to drive innovation in drug discovery and development. The group collaborates broadly within our... 
    Principal
    Full time
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    Rahway, NJ
    12 days ago
  • Merck & Co., Inc. in Rahway, NJ, is seeking a Senior Principal Scientist/Principal Scientist to lead upstream bioprocess development for biologics...  ..., drive innovation, and guide a team of scientists across Discovery to Commercial Manufacturing. The role demands deep cell-... 
    Principal

    Merck & Co.

    Rahway, NJ
    1 day ago
  • $173.2k - $272.6k

     ...Research and Development division, quantitative scientists, in partnership with other subject matter...  ...methodologies and tools to enable the discovery, development, regulatory approval, manufacturing, and marketing of medical drugs and vaccines for the benefit of patients... 
    Principal
    Full time
    For contractors
    Local area
    Flexible hours

    Merck Sharp & Dohme (MSD)

    Rahway, NJ
    1 day ago
  • $173.2k - $272.6k

     ...Division is responsible for developing the drug substance manufacturing processes for...  .... We work closely with colleagues in Discovery, Pre-clinical and Early Development to...  ...experienced individual to join our team as a Principal Scientist. In this role, the successful candidate... 
    Principal
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co. , Inc.

    Rahway, NJ
    1 day ago
  • $260.3k - $409.7k

     ...exciting opportunity for a physician-scientist to join our group as a Principal Scientist (Clinical Director) in...  ...working in close collaboration with our discovery scientists and late-stage clinical...  ...discovery research, biostatistics, drug metabolism, modeling and simulation... 
    Principal
    Full time
    For contractors
    Local area
    Worldwide
    Flexible hours

    Merck Sharp & Dohme (MSD)

    Rahway, NJ
    4 days ago
  • $142.4k - $224.1k

     ...review of Chemistry, Manufacturing and Control submission components and documentation to support approval supplements/variations, Drug Master Files, New Drug Application/Biologics License Application/Marketing Authorization Application, Annual Reports, Commitment and... 
    Principal
    Full time
    Contract work
    For contractors
    Local area

    Merck Sharp & Dohme (MSD)

    Rahway, NJ
    2 days ago
  • $142.4k - $224.1k

    Job DescriptionAssociate Principal Scientist, Regulatory CMC - Biologics (R4)This Associate Principal Scientist position is equivalent to an Associate...  ...Controls regulatory guidelines regarding Investigational New Drug Applications, Biologics License Applications, and post-... 
    Principal
    Full time
    For contractors
    Local area
    Visa sponsorship
    Flexible hours

    Merck Sharp & Dohme (MSD)

    Rahway, NJ
    1 day ago
  • $255.8k - $402.7k

    Job DescriptionJob DescriptionThe Clinical Director (Principal Scientist) has primary responsibility for planning and directing clinical research...  ...decisions regarding safety and efficacy as well as new drug applications, clinical study reports, or publicationParticipating... 
    Principal
    Full time
    For contractors
    Local area
    Flexible hours

    Merck Sharp & Dohme (MSD)

    Rahway, NJ
    4 days ago
  • $255.8k - $402.7k

    Job DescriptionThe Clinical Director (Principal Scientist) has primary responsibility for the strategic planning and directing clinical research...  ...the early clinical development plan and Investigational New Drug applications.Providing clinical development support of... 
    Principal
    Full time
    For contractors
    Local area
    Flexible hours

    Merck Sharp & Dohme (MSD)

    Rahway, NJ
    8 hours ago
  • $190.8k - $300.3k

     ...DescriptionJob Description:Our Scientists are our Inventors. Through...  ...Development (BPR&D) as a Senior Principal Scientist.BPR&D within our...  ...work closely with colleagues in Discovery, Pre-clinical, Early...  ...and recombinant expression of drug candidates in early- and late... 
    Principal
    Full time
    For contractors
    Local area
    Visa sponsorship
    Flexible hours

    Merck Sharp & Dohme (MSD)

    Rahway, NJ
    1 day ago
  • $173.2k - $272.6k

     ...Labs is responsible for developing the drug substance manufacturing processes for our...  .... We work closely with colleagues in Discovery, Pre-clinical and Early Development to...  ...our Upstream Development Department as a Principal Scientist. In this role, the successful candidate... 
    Principal
    Full time
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    Rahway, NJ
    a month ago
  • $156.9k - $247k

     ...lifecycle management. This person will lead several Human Factors scientists to perform and manage human factors activities to ensure...  ...post-market surveillance.Key Responsibilities and Activities:The Principal Scientist is responsible for managing a Human Factors team... 
    Principal
    Full time
    For contractors
    Local area
    Flexible hours

    Merck Sharp & Dohme

    Rahway, NJ
    6 days ago
  • $145.48k - $224.1k

    Job Description Responsibilities: Provide high quality statistical programming analysis and reporting deliverables for global stakeholders, within our Research and Development division. Gather and interpret user requirements for analysis and programming requests...
    Principal
    Full time
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    Rahway, NJ
    a month ago
  • $145.48k - $224.1k

     ...Job Description DUTIES: ~ Support statistical programming activities for multiple and/or late-stage drug/vaccine clinical development projects. ~ Develop and execute statistical analysis and report deliverables (e.g., safety and efficacy analysis datasets, tables... 
    Principal
    Full time
    For contractors
    Local area
    Remote work
    Worldwide
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    Rahway, NJ
    8 days ago
  • $142.4k - $224.1k

     ...investors in Research & Development. We are seeking an Associate Principal Scientist to join our Process Modeling & Analytics team within the...  ...of new digital tools/workflows to support scientists across drug substance development, drug product development and... 
    Principal
    Full time
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    Rahway, NJ
    21 days ago
  • $142.4k - $224.1k

     ...Laboratories is responsible for developing the drug substance manufacturing processes for...  .... We work closely with colleagues in Discovery, Pre-clinical and Early Development to...  ...Development Department as an Associate Principal Scientist.- Applicant must have effective... 
    Principal
    Full time
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    Rahway, NJ
    a month ago
  • $142.4k - $224.1k

     ...of Position The Regulatory Affairs Headquarters Associate Principal Scientist supports products in the Vaccine and Infectious Disease (VID)...  ...not limited to: marketing applications, Investigational New Drug Applications (INDs), pediatric plans and annual or other periodic... 
    Principal
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    Rahway, NJ
    8 days ago
  • $55 - $68 per hour

     ...Job Description Job Description Principal Scientist, NA Skin Health & Consumer Science Kelly Science and Clinical has an opening for...  ...If you’re passionate about bringing the latest scientific discoveries to life and are ready to take the next step in your career,... 
    Principal
    Temporary work
    Work experience placement
    Local area

    Kelly Services

    Summit, NJ
    7 days ago
  • $190.8k - $300.3k

     ...seeking an accomplished and highly motivated Principal Scientist to provide strategic and scientific...  ...making. - Partner closely with Discovery, Clinical Development, Quantitative Sciences...  ...medicine, biomarker science, drug development, or a related discipline.... 
    Principal
    Full time
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    Rahway, NJ
    14 days ago
  • $145.48k - $224.1k

     ...Job Description DUTIES: ~ Support statistical programming activities for multiple and/or late-stage drug/vaccine clinical development projects. ~ Develop and execute statistical analysis and report deliverables (e.g., safety and efficacy analysis datasets, tables... 
    Principal
    Full time
    For contractors
    Local area
    Remote work
    Worldwide
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    Rahway, NJ
    6 days ago
  • $142.4k - $224.1k

     ...Research and Development division, quantitative scientists, in partnership with other subject matter...  ...methodologies and tools to enable the discovery, development, regulatory approval, manufacturing, and marketing of medical drugs and vaccines for the benefit of patients... 
    Principal
    Full time
    For contractors
    Local area
    Worldwide
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    Rahway, NJ
    20 days ago
  • $260.3k - $409.7k

     ...therapeutics, working in close collaboration with Discovery Sciences and late-stage Clinical...  ...Disease and related conditions. The Principal Scientist (Clinical Director) must have a strong...  ...including discovery research, biostatistics, drug metabolism, modeling and simulation,... 
    Principal
    Full time
    For contractors
    Local area
    Worldwide
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    Rahway, NJ
    14 days ago
  • $140.2k - $169.89k

     ...the careers of those who do it. Business Unit Overview Our Drug Product Development team is committed to CMC design,...  ...uncommon in scale and scope. Position Summary The Senior Principal Scientist for Solid Oral Dose Packaging is a senior role within our pharmaceutical... 
    Principal
    Hourly pay
    Full time
    Summer work
    Live in
    Local area
    Remote work
    Flexible hours

    Bristol Myers Squibb

    New Brunswick, NJ
    1 day ago
  • $190.8k - $300.3k

     ...Description Job Description: Our Scientists are our Inventors. Through...  ...(BPR&D) as a Senior Principal Scientist. BPR&D within our...  ...work closely with colleagues in Discovery, Pre-clinical, Early...  ...and recombinant expression of drug candidates in early- and late... 
    Principal
    Full time
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    Rahway, NJ
    16 days ago
  • $117k - $184.2k

     ...organizational, interpersonal, writing, and time management skillsPreferred Experience and Skills:Direct experience with pharmaceutical drug substance processingFamiliarity with concepts and application of cGMP and GDocP during pharmaceutical development and production.... 
    Full time
    For contractors
    Work experience placement
    Local area
    Flexible hours

    Merck Sharp & Dohme (MSD)

    Rahway, NJ
    3 days ago
  • $82k - $92k

     ...Fellow - Quantitative Biosciences Early Discovery Join the Legacy: Postdoctoral Research...  ...motivated and innovative research scientist for a Postdoctoral Fellowship in the Department...  ...role, the fellow will pioneer novel drug discovery methodologies in the rapidly expanding... 
    Full time
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    Rahway, NJ
    4 hours ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal Scientist, Drug Discovery. Be the first to apply!