IT Operations Manager (Boston)

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Bicara Therapeutics is seeking a hands-on IT Operations Manager to lead and optimize our cloud and on-premises IT infrastructure and service desk operations. As the second IT hire, this role requires both technical expertise and leadership, balancing day-to-day IT operations, service management, and long-term IT growth strategy.

Reporting to the Head of Information Technology, the IT Operations Manager will be responsible for maintaining enterprise systems, managing IT service delivery, and ensuring a secure, efficient technology environment. Over time, this individual will play a key role in expanding the IT department, helping to define the technical roadmap and assisting IT leadership in growing the team. We are ideally seeking Massachusetts-based candidates who are able to work a hybrid schedule that includes 3 days per week in our Boston office.

Responsibilities:

IT Infrastructure & Hands-On System Administration

• Act as a technical lead while managing enterprise systems, network servers, and cloud environments.
• Be actively involved in troubleshooting, system upgrades, and automation efforts.
• Implement and manage tools for endpoint and mobile device management.
• Ensure robust data protection, disaster recovery, and failover processes.
• Automate and streamline IT processes, including onboarding/offboarding, ticket resolution, and infrastructure management.
• Manage IT vendor and SaaS relationships, including service providers for building IT, AV, and network design.
• Serve as the primary IT support resource, resolving escalated technical issues hands-on.
• Oversee end-user computing support across desktops, laptops, mobile devices, and cloud applications.
• Develop IT operational standards, including Service Level Agreements (SLAs), Incident, Problem, Change, and Knowledge Management processes.
• Establish documentation, training programs, and best practices to enhance technical knowledge and user support.

Security & Compliance

• Ensure compliance with SOX, GITC, and GxP regulatory standards.
• Enforce security best practices, including access controls, data encryption, and endpoint protection.
• Identify and mitigate risks, manage IT change processes, and maintain a secure and resilient IT infrastructure.

Strategic Growth & IT Expansion

• Partner with the Head of IT to develop the long-term IT strategy and grow the IT department as the company scales.
• Assist in identifying staffing needs, hiring plans, and technical roadmaps to build a world-class IT team.
• Provide technical mentorship and leadership, ensuring IT solutions align with business needs.
• Lead IT projects, balancing strategic planning with hands-on execution.

Qualifications:

Required:

• 5+ years of hands-on IT experience in system administration, IT operations, and service desk management.
• Strong technical expertise in Windows/Linux servers, VMware, AWS, Office 365, and enterprise SaaS solutions.
• Hands-on experience with networking, cybersecurity, and infrastructure automation.
• Proficiency in PowerShell, Python, or other scripting languages for automation and DevOps tasks.
• Proven ability to manage IT vendors, SaaS providers, and service agreements.
• Strong leadership skills, with experience managing IT service delivery and end-user support.
• Excellent problem-solving, communication, and customer service skills.

Preferred:

• Industry certifications (e.g., AWS, Microsoft, Cisco, ITIL, Security+).
• Experience in biotech, pharmaceutical, or research-driven environments.
• Understanding of IT Service Management (ITSM) and ITIL frameworks.
• Experience with cloud security, DevOps methodologies, and infrastructure-as-code.

Company Overview

Bicara Therapeutics is a clinical-stage biopharmaceutical company committed to bringing transformative bifunctional therapies to patients with solid tumors. Bicara’s lead program, ficerafusp alfa, is a bifunctional antibody that combines two clinically validated targets, an epidermal growth factor receptor (EGFR) directed monoclonal antibody with a domain that binds to human transforming growth factor beta (TGF-β). Through this dual-targeting mechanism, ficerafusp alfa has the potential to exert potent anti-tumor activity by simultaneously blocking both cancer cell-intrinsic EGFR survival and proliferation, as well as the immunosuppressive TGF-β signaling within the tumor microenvironment. Ficerafusp alfa is being developed in head and neck squamous cell carcinoma, where there remains a significant unmet need, as well as other solid tumor types. For more information, please visit or follow us on LinkedIn or X.

Here at Bicara, we believe in building diverse teams and cultivating a culture where all voices are included. We encourage people from all backgrounds to apply.

Bicara Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Information Technology

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