Senior Medical Science Liaison, Northeast (Multiple Territories)

Senior Medical Science Liaisons (MSL)

Praxis is seeking a field-based Senior Medical Science Liaisons (MSL) to support prelaunch and launch activities. This role will focus on building trusted relationships with investigators and key stakeholders, delivering high-quality scientific exchange, and ensuring clinical and account readiness in advance of and following potential approval.

You will play a critical role in translating clinical data into meaningful insights for the field, educating healthcare professionals on disease state and emerging data, and identifying opportunities and barriers that may impact adoption. Working cross-functionally with Medical, Clinical Development, and Commercial teams, you will help shape and execute field strategy in a dynamic, fast-moving launch environment.

This is not a passive, reactive role you are expected to operate with a high degree of ownership, proactively generate insights, and influence the field through credible, science-driven engagement.

We are open to hiring across levels and seek individuals who can operate independently in the field whether developing into the role or already leading at a high level. Leveling will reflect experience, judgment, and the ability to drive impact in a prelaunch/launch setting.

Success in this role requires strong clinical credibility, excellent communication skills, strategic thinking, and comfort operating autonomously in a fast-paced environment.

Primary responsibilities include serving as the primary field-based scientific partner to investigators and key stakeholders, delivering high-quality scientific exchange on disease state, clinical data, and the ulixacaltimide profile, educating and preparing clinical sites and healthcare providers for launch, proactively gathering, synthesizing, and communicating field insights, identifying and engaging key opinion leaders, partnering cross-functionally with teams to align on and execute field strategy, representing Praxis at scientific congresses and advisory engagements, maintaining deep expertise in CNS/neurology, and ensuring all field activities are conducted in compliance with regulatory requirements.

Qualifications and key success factors include an advanced clinical or scientific degree, experience in medical affairs, clinical research, clinical care, or field-based roles within biotech/pharma, demonstrated ability to interpret and communicate complex scientific and clinical data, strong ownership mindset, proven ability to build and maintain trusted relationships with healthcare professionals, experience gathering and translating field insights into actionable recommendations, ability to manage multiple priorities, willingness and ability to travel extensively, experience in neurology or CNS disorders preferred, and experience within market access/payor landscape is preferred.

Candidates with prior field-based experience and a demonstrated track record of independently driving scientific engagement, shaping clinical perspectives, and contributing to successful pre-launch and launch activities will be considered at a higher level.

Annualized base salary $190,000 $220,000 USD

Compensation & benefits at Praxis include 99% of the premium paid for medical, dental and vision plans, company-paid life insurance, AD&D, disability benefits, voluntary plans to personalize coverage, dollar-for-dollar match on eligible 401(k) contributions, long-term stock incentives and ESPP, discretionary quarterly bonus, flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns.

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.

Diversity, equity & inclusion guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.

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