Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Founding Engineer, Backend & Infra

Backbone

Founding Engineer, Backend & Infrastructure

About Backbone

Care should be paid for the moment it’s delivered. At Backbone, we’re making that possible for the first time by building the clinical AI layer for healthcare payments.

Today, U.S. healthcare wastes more than $350B yearly on administrative work that has nothing to do with patient care: prior authorizations, denials, appeals, and the staff hired on both sides of the aisle to adjudicate and determine payment for services rendered. As a result, patient care is delayed, clinicians burn out, margins crater, and hundreds of billions of dollars that should be funding care end up funding the friction itself.

Backbone is dismantling this friction, building intelligent financial rails atop clinical AI research to facilitate instant payments between payers and providers. We\'re backed by Andreessen Horowitz (a16z), Lightspeed, Hanabi, and a roster of operators and clinicians who have built and run the largest payers, providers, and healthcare technology platforms in the country. Our founder/CEO, Manan Shah, holds a BS/MS in Math & CS from Stanford and led ML infrastructure at Sequoia-backed Kumo AI, where he built graph neural networks serving DoorDash, Reddit, and Coinbase.

Backbone’s revenue is growing quickly, customer demand is outpacing our team, and the road ahead is bright.

What you’ll do

As a founding engineer, you’ll own the systems that make Backbone work: chart ingestion, document processing, claims workflows, browser and computer-use automation, payer portal navigation, orchestration, queues, reliability, auditability, and the infrastructure needed to scale from thousands of charts and claims to hundreds of thousands.

You will:

  • Build and scale the distributed systems that power Backbone’s clinical and financial workflow; own backend services across chart data, claims data, authorization workflows, denial workflows, and payer/provider integrations

  • Build orchestration infrastructure for long-running, failure-prone workflows across EHRs, practice management systems, clearinghouses, and payer portals

  • Work on browser-use and computer-use systems that navigate complex medical software and payer portals

  • Design reliable systems for messy healthcare data: scanned charts, PDFs, structured claims, unstructured notes, attachments, policies, and operational state

  • Build observability, retry, audit, and human-in-the-loop infrastructure for high-stakes production workflows

  • Partner with product and research engineers to take new clinical intelligence capabilities into production, and set the engineering patterns that future engineers will inherit

What we’re looking for

  • 3+ years of professional software engineering experience shipping production systems end-to-end

  • Generalist range across backend, data, and ML, alongside real LLM experience in production

  • Comfort with distributed systems, microservices, queues, workflow engines, data pipelines, or large-scale backend infrastructure

Healthcare experience is helpful, but not required. Curiosity, rigor, and taste matter more.

Why join

This is a chance to join early and help define both the product and the engineering culture.

You’ll work on hard, practical problems: turning fragmented healthcare workflows into software that actually helps people do their jobs faster and better. Your work will touch product decisions, system architecture, user experience, and the core automation engine behind Backbone.

We offer competitive compensation, meaningful ownership, and the opportunity to build foundational technology in a massive, broken, high-impact industry.

#J-18808-Ljbffr

Vacancy posted 1 day ago
Similar jobs that could be interesting for youBased on the Founding Engineer, Backend & Infra in San Francisco, CA vacancy
  •  ...Location: San Francisco, CA (On-site, 5 days/week) Role We're looking for a backend-leaning Founding Engineer (0-7 years experience) who has shipped production software at a pedigreed company — FAANG, high-growth VC-backed startups (Series A+), or equivalent. You... 
    Suggested
    Relocation

    Remotestar

    San Francisco, CA
    1 day ago
  •  ...funds this hire. The role: You’re the first engineering hire. The next 18 months are about...  ...autonomous and agentic platform. You’ll own backend architecture decisions from day one. The...  ...Competitive base salary + meaningful founding equity. #J-18808-Ljbffr Quin AI
    Suggested

    Quin AI

    San Francisco, CA
    3 days ago
  • $200k - $300k

     ...About the Role Own the backend systems behind an AI assistant that communicates through text, email, and phone. As a hands‑on founding engineer, you will design, build, and operate reliable infrastructure for message delivery, long‑running agent tasks, and scheduled... 
    Suggested
    Immediate start

    Clera

    San Francisco, CA
    1 day ago
  •  ...candidate profiles across active roles and use resumes/profiles to understand which backgrounds may be a fit. THE ROLE As a Founding Backend Engineer, you may work on projects that require strong execution, communication, analytical judgment, and the ability to move... 
    Suggested

    Career-Launch.net

    San Francisco, CA
    3 days ago
  • $200k - $300k

     ...the traffic grows every week. This is a hands-on engineering role. You’ll design it, build it, run it, and get paged...  ..., correct, and own everything you ship. ~ You want founding-team scope. You’ll set the backend bar for Pally and help hire the engineers who join... 
    Suggested
    Full time

    Pally

    San Francisco, CA
    1 day ago
  •  ...Design, develop, and maintain scalable backend services to help us serve millions of users...  ...new features. Collaborate with frontend engineers to design and implement RESTful APIs and...  ...Previous experience as a founder or founding engineer is highly preferred. Hard skills... 
    Contract work
    Work experience placement
    Work at office
    Immediate start

    RainesDev

    San Francisco, CA
    1 day ago
  • Valerie Health is seeking a founding engineer in San Francisco to help shape the technical foundation of a healthcare AI startup. You will build a robust backend, integrate AI models across modalities, and craft polished user experiences that scale from inception to growth... 

    Valerie Health

    San Francisco, CA
    1 day ago
  • A promising startup in San Francisco is seeking a Founding Engineer to join their team. In this role, you'll take ownership of building and scaling backend systems using Python and TypeScript, while collaborating closely with founders. Ideal candidates should have 1-5 years... 
    Weekday work

    Weekday AI (YC W21)

    San Francisco, CA
    3 days ago
  •  ...toward agents that improve on their own. Litmus was founded in August 2026 by Sidharth Srinivasan, who built and led...  ...being invented. You might be a fit if You're a strong backend or infrastructure engineer who has been early before You've built and run... 
    Work at office
    Relocation package

    US Health Partners, LLC

    San Francisco, CA
    1 day ago
  •  ...Job Description Job Description We are hiring a Founding Software Engineer in San Francisco. We are building a small, talent-dense team...  ...developer experience. Architect, build, and scale core backend systems powering document intelligence and VLM-based workfows... 

    Unsiloed AI

    San Francisco, CA
    a month ago
  •  ...powers the company’s generative media ecosystem. We seek a founding backend platform engineer to own billing, pricing, accounts, access, API keys, and...  ...trust. A pivotal role with broad impact across product, infra, finance, and security. #J-18808-Ljbffr The Consensus

    The Consensus

    San Francisco, CA
    2 days ago
  • $200k - $260k

    Matterhaul Inc. is seeking a founding infrastructure engineer based in San Francisco to rebuild their infrastructure and core systems from scratch...  ...Golang, deep AWS knowledge, and a track record in building backend systems. This is a full-time position with a competitive... 
    Full time

    Matterhaul, Inc.

    San Francisco, CA
    1 day ago
  •  ...largest healthcare enterprises. Experienced founding team: Built by exited founders, YC & MIT alum, ex-Tesla, ex-Google engineers. Hypergrowth with stability: We went from...  ...to the patients who need them. Keywords: Senior Backend Engineer, Sr. Backend Engineer... 
    Live in
    Night shift

    Neon | Ai-powered Patient Access

    San Francisco, CA
    2 days ago
  • Sphere is building AI-native trade infrastructure and seeks a senior infra engineer in San Francisco to tackle scaling and latency challenges across critical billing and tax-automation systems. You’ll collaborate with engineering, own cloud-native architecture, and work... 

    Getsphere

    San Francisco, CA
    1 day ago
  • Oho Group is building a platform where people and AI agents work together. We’re hiring a Founding Engineer to shape the backend infrastructure that lets agents execute complex tasks reliably, coordinate with each other and keep humans involved. This role offers an equity... 

    Oho Group

    San Francisco, CA
    16 hours ago
  • $225k - $275k

     ...About the Role Join an early-stage AI video team as a founding backend engineer, shaping the systems behind its video generation and creative technology. You will serve as a technical lead, setting a high bar for engineering quality and helping guide the team's technical... 
    Full time

    True Talent Solutions Partners

    San Francisco, CA
    1 day ago
  • Backbone is building the clinical AI layer for healthcare payments. Founding Engineer, Backend & Infrastructure will own the systems that power Backbone’s clinical and financial workflows, including chart and claims data, authorization, denial handling, and payer/provider... 

    Backbone

    San Francisco, CA
    5 days ago
  • $192k - $260k

     ...central to their own missions.Founded in 2013 by the original...  ...SaaS companies in the world.Our engineering teams build highly technical...  ...As a software engineer with a backend focus, you will work closely...  ...clouds and environments.Core Infra: Build the core infrastructure... 
    Work at office
    Local area
    Worldwide
    Flexible hours

    DataBricks

    San Francisco, CA
    5 days ago
  • $225k - $275k

     ...About the Role Join an early-stage AI video company as a founding backend engineer. You will lead the design of the systems behind AI-powered video creation, working closely with researchers, engineers, and designers to build new product capabilities. What You'll Do... 
    Full time

    True Talent Solutions Partners

    San Francisco, CA
    1 day ago
  • $200k - $325k

    Aionia Group in San Francisco seeks a founding team member to architect and ship production-grade AI...  ...into scalable implementations and maintaining backend services and APIs. Candidates should have strong backend engineering skills, a relevant degree, and be comfortable... 

    Aionia Group

    San Francisco, CA
    1 day ago
  • Town is hiring its founding technical recruiter to own how we find, engage, and close engineers who will define the company. You’ll partner with the founders and...  ...most important technical searches across backend, AI product, infra, and related roles. You’ll help build the... 

    Town

    San Francisco, CA
    2 days ago
  • True Talent Solutions Partners in San Francisco is seeking an experienced backend infrastructure engineer to own production systems for high-volume web extraction. You will architect proxy rotation, IP management, and egress isolation to keep data flowing even as sites... 

    True Talent Solutions Partners

    San Francisco, CA
    1 day ago
  • A leading AI startup in San Francisco is seeking a Lead Founding Backend Engineer to architect and implement the core backend systems for a consumer AI social platform. You will design high-performance infrastructure while collaborating on frontend features. The ideal candidate... 

    Alpha-Tx Solutions LLC

    San Francisco, CA
    4 days ago
  • $150k - $250k

    # Founding AI Infrastructure EngineerRemote (US) or Hybrid (SF Bay Area)Full-time$150...  ...production and we're bringing on exceptional engineers to build the infrastructure that makes...  ...judgment* •4+ years experience in backend/platform/infra roles (or equivalent depth)* •Comfort... 
    Full time

    Harden

    San Francisco, CA
    1 day ago
  • $227.2k - $324.5k

     ...the Role:As a Staff Software Engineer on the ML Infrastructure team...  ...cost, and efficiency of our infra. Lead large scale cross functional...  ...systems in any modern backend language (e.g., Scala, Java,...  ...Headquartered in San Francisco and founded in 2014, Tubi is part of Tubi... 
    Full time
    Temporary work
    Local area
    Flexible hours

    Tubi TV

    San Francisco, CA
    5 days ago
  • $180k - $250k

     ...About the Role Join a small engineering team building agentic systems for an AI-native legal services business. In this founding-level role, you will work across the stack to deliver...  ...regulated-industry experience, plus backend observability experience, is helpful.... 
    Full time

    True Talent Solutions Partners

    San Francisco, CA
    16 hours ago
  •  ...8 years Stage: Seed → Series B Role Type: Early hire / founding engineer Why This Role Exists You’ll help build the core product...  ...Do Build end-to-end product features across frontend and backend Ship quickly in 0→1 environments Design APIs, schemas,... 

    Weekday

    San Francisco, CA
    a month ago
  • $160k - $200k

     ...contribute both to our mobile application and backend for our Guaranteed Income product. The...  ...admin portal. You will work with our engineering team to design, develop, test, and...  ...and team culture. ~ Funding $4.6M ~ Founded 2018 ~ Salary: $160k - $200k ~100% US... 
    Work at office
    Remote work

    Hired Recruiters

    San Francisco, CA
    1 day ago
  • $100k - $180k

     ...stack, from React interfaces to Python backend systems. What We're Looking For Experience...  ...and TypeScript skills, with full-stack engineering ability. Proficiency in Python and...  ...depth. Experience as a founder, founding engineer, or early startup employee is valued... 
    Full time

    Clera

    San Francisco, CA
    1 day ago
  • $200k - $300k

     ...Francisco in the search for a highly skilled Senior/Staff Founding Full-Stack Engineer – Agent Systems. The successful candidate will join the...  ...agent execution. While the position is heavily focused on backend engineering and systems, the successful candidate will own... 
    Full time
    H1b
    Work at office
    Visa sponsorship
    Monday to Friday

    People Hive HR Consultancies LLC

    San Francisco, CA
    1 day ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Founding Engineer, Backend & Infra. Be the first to apply!