Bioinformatics Scientist

Job Family:Scientific Research & AnalysisTravel Required:NoneClearance Required:Ability to Obtain Public TrustWhat You Will Do:We are currently searching for Bioinformatics Scientist to provide bioinformatics support to advance the institute research programs, with a primary focus on single cell and spatial omics data analysis. This is a full-time, on-site opportunity in Durham, NC. Collaborate with scientists to design, analyze, manage and interpret all types of data. Conduct analyses on NextGen sequencing data including data derived in ChIP-Seq,RNA-Seq, miRNA-Seq and other experimental models. Work with an interdisciplinary team to apply computational data analysis approaches to make biological discoveries. Conduct analysis and interpretation on data from genomic platforms including expression, exon, tiling, promoter and others array types. Work independently with research groups to develop, implement, and refine analytical pipeline for single cell data analysis. Develop, optimize, and maintain bioinformatics pipelines, scripts, and computational tools for large-scale data analysis (e.g., NGS, scRNA-seq, multi-omics). Perform advanced statistical and computational analyses to interpret complex datasets and derive actionable biological insights. Collaborate with scientists and researchers to design experiments, select appropriate analytical approaches, and troubleshoot methodologies. Integrate and analyze diverse genomic and multi-omic datasets, including sequencing and public data sources. Install, configure, and support scientific software across computing platforms; ensure reproducibility through standardized workflows and documentation. Generate reports, visualizations, and presentations to communicate findings to scientific and technical audiences. Evaluate and implement new bioinformatics tools, statistical methods, and computational approaches based on current literature and research needs. Provide training and technical guidance to staff on bioinformatics tools, pipelines, and data analysis techniques. Maintain detailed documentation, laboratory records, and progress reports; present findings at meetings and contribute to publications. Support interdisciplinary collaborations and contribute to advancing research objectives aligned with organizational mission. Must be able to obtain and maintain a Federal or DoD “public trust”; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred.What You Will Need:Master’s degree in bioinformatics, biostatistics, computational biology or biological/life science. At least TWO (2) years of data analysis experience. Advanced proficiency in disciplines such as statistical modeling, machine learning, and integrative analysis to extract biologically meaningful insights from complex cellular systems. Knowledgeable with a variety of next gen sequencing techniques. Experience working with analytical tools, software and platforms such as, but not limited to, R, Python, MATLAB, SAS, PERL, Java, Shell, Bash, Seurat / Scanpy, Linux, Unix, Bioconductor, Cloud computing, High-Performance Computing (HPC). Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must obtain approved adjudication of their public trust prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferredWhat Would Be Nice To Have:PhD preferred Strong verbal and written communication skills Familiar with multiple next gen sequencing techniques Ability to collaborate closely with investigators and multidisciplinary teams to design analytical strategies, ensure data quality, interpret results, and translate findings into actionable scientific conclusions. What We Offer:Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.Benefits include:Medical, Rx, Dental & Vision InsurancePersonal and Family Sick Time & Company Paid HolidaysParental Leave401(k) Retirement PlanGroup Term Life and Travel AssistanceVoluntary Life and AD&D InsuranceHealth Savings Account, Health Care & Dependent Care Flexible Spending AccountsTransit and Parking Commuter BenefitsShort-Term & Long-Term DisabilityTuition Reimbursement, Personal Development, Certifications & Learning OpportunitiesEmployee Referral ProgramCorporate Sponsored Events & Community OutreachCare.com annual membershipEmployee Assistance ProgramSupplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)Position may be eligible for a discretionary variable incentive bonusAbout GuidehouseGuidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at View phone number on click.appcast.io or via email at View email address on click.appcast.io. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or View email address on click.appcast.io. Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse. Note that Guidehouse will never charge a fee or require a money transfer at any stage of the recruitment process and does not collect fees from educational institutions for participation in a recruitment event. Never provide your banking information to a third party purporting to need that information to proceed in the hiring process.If any person or organization demands money related to a job opportunity with Guidehouse, please report the matter to Guidehouse’s Ethics Hotline. If you want to check the validity of correspondence you have received, please contact View email address on click.appcast.io. Guidehouse is not responsible for losses incurred (monetary or otherwise) from an applicant’s dealings with unauthorized third parties.Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.SummaryLocation: US - NC, DurhamType: Full time