Scientist II - 30950

Job Description

Job Description

BEPC is actively looking for a Scientist II – Cell Therapy Research in South San Francisco, CA area!

W2 Contract – 12 months, with possible extensions!

Benefits include medical, dental, vision, and life insurance.

Pay Rate: $59.94 – $62.94/hour – Determined based on experience. (Paid weekly)

Work Model: Laboratory-based, onsite position

Work Schedule: Monday–Friday, 9:00 AM–5:00 PM

Work Location: South San Francisco, CA 94080

Interview Process: Initial phone screening followed by an in-person panel interview.

Note: This is a W2 only role — C2C, C2H will not be considered.

Summary of the Position

BEPC is seeking a highly motivated Scientist II to join our client’s site in South San Francisco, CA. This role will support in vivo cell therapy research through hands-on laboratory activities focused on research-scale lentiviral vector production, vector characterization, and analytical assay development.

The Scientist II will be responsible for developing and optimizing lentiviral vector production workflows, performing molecular and cell-based analytical assays, and supporting research programs involving gene delivery and cell engineering. The role may also involve generating and characterizing materials for preclinical in vivo studies conducted by collaborating teams; however, this position does not involve conducting animal studies.

The ideal candidate will demonstrate strong experimental judgment, technical expertise in lentiviral vector production and cell-based analytics, scientific curiosity, and the ability to independently troubleshoot experiments while collaborating effectively with multidisciplinary research teams.

Main Duties and Responsibilities

• Execute and optimize research-scale lentiviral vector production workflows, including approaches that increase production capacity and support the transition to suspension culture.
• Produce and characterize research-grade lentiviral vectors for in vitro evaluation and, as needed, to support preclinical in vivo studies.
• Develop, optimize, and execute molecular and cell-based analytical assays to assess vector quality, titer, gene delivery, CAR expression, and functional activity.
• Perform primary human cell culture and engineering studies to evaluate delivery platforms for in vivo cell therapy applications.
• Apply flow cytometry techniques to assess transduction efficiency, CAR expression, and cell phenotype.
• Collaborate with project teams to define material requirements, coordinate production timelines, and provide supporting analytical data.
• Independently plan and execute experiments, troubleshoot technical challenges, and interpret results in collaboration with project team members.
• Analyze experimental findings and communicate results through clear scientific summaries and presentations at internal scientific meetings.
• Maintain accurate and timely electronic laboratory records, document experimental methods, and contribute to the development of reproducible laboratory workflows.
• Support laboratory operations, including equipment onboarding and maintenance.
• Follow applicable biosafety, laboratory safety, and training requirements.

Main Qualifications

• Education: Bachelor's or Master's degree with at least 5 years of industry experience, or a PhD in Immunology, Virology, Molecular Biology, Bioengineering, Cell Biology, or a related discipline.
• Experience: Hands-on experience with lentiviral vector production and characterization.
• Strong proficiency in aseptic mammalian cell culture techniques.
• Experience working with primary human immune cells, preferably T cells.
• Experience developing, optimizing, and troubleshooting molecular or cell-based analytical assays.
• Technical proficiency in flow cytometry.
• Experience with at least one quantitative molecular assay platform, such as qPCR or ddPCR.
• Demonstrated ability to independently design experiments, critically interpret experimental data, and resolve technical challenges.
• Strong organizational skills and attention to detail, particularly in laboratory documentation and experimental recordkeeping.
• Excellent written and verbal communication skills.
• Ability to manage concurrent experiments and collaborate effectively with multidisciplinary scientific teams.
• Self-motivated approach to laboratory research, with strong scientific curiosity and experimental judgment.

Preferred Qualifications

• Three or more years of relevant post-graduate research experience in biotechnology, pharmaceutical research, or an academic setting.
• Experience producing or characterizing gene delivery vectors for in vivo CAR T or related preclinical research programs.
• Experience with suspension-based lentiviral vector production, scale-up, or process development.
• Experience with CAR T-cell functional assays and multiparameter flow cytometry.
• Experience with nonviral delivery platforms, genome engineering, or next-generation sequencing.
• Familiarity with automation, liquid handling systems, and high-throughput analytical workflows.
• Proficiency with relevant data analysis and documentation tools, such as FlowJo, GraphPad Prism, and Benchling.

About BEPC

BEPC Inc., founded in 2007, is a 100% employee-owned company providing top-tier consulting and staffing solutions across industries like technology, engineering, manufacturing, and project management. At BEPC, we are driven by innovation and a commitment to excellence. We take pride in fostering a collaborative and innovative environment where our team members thrive. With competitive benefits, including medical, dental, vision, and life insurance, BEPC is dedicated to supporting our employees' personal and professional growth.

Apply Now!

Company Description

About BEPC

BEPC Inc., founded in 2007, is a 100% employee-owned company providing top-tier consulting and staffing solutions across industries like technology, engineering, manufacturing, and project management. At BEPC, we are driven by innovation and a commitment to excellence. We take pride in fostering a collaborative and innovative environment where our team members thrive.

With competitive benefits, including medical, dental, vision, and life insurance, BEPC is dedicated to supporting our employees' personal and professional growth.

Company Description

About BEPCBEPC Inc., founded in 2007, is a 100% employee-owned company providing top-tier consulting and staffing solutions across industries like technology, engineering, manufacturing, and project management. At BEPC, we are driven by innovation and a commitment to excellence. We take pride in fostering a collaborative and innovative environment where our team members thrive.With competitive benefits, including medical, dental, vision, and life insurance, BEPC is dedicated to supporting our employees' personal and professional growth.