Vice President, Global Commercial Strategy Lead, Inflammation & Immunology + Rare Disease

Position Overview

The Vice President, Global Commercial Strategy Lead for Inflammation & Immunology (I&I) and Rare Disease is responsible for driving long-range commercial strategy, portfolio management, and commercial success across both pipeline and inline brands. This role serves as the single, authoritative commercial voice to R&D, Business Development, and US & International Commercial Regions , establishing clear commercial leadership to improve portfolio decision-making and trade-offs, ensure optimal launch and brand marketing strategies, and maximize global patient impact and enterprise value realization for our I&I and Rare Disease portfolio.

Reporting to the Global Commercial Strategy Lead, this leader shapes decisions on I&I and Rare Disease portfolio prioritization, lifecycle value optimization, and global marketing strategy. The position partners closely with R&D, Medical Affairs, Global Access & Value, and Regional Commercial teams to deliver breakthrough therapies addressing autoimmune, inflammatory, and rare diseases.

Success in this role requires a senior commercial strategist who combines scientific depth with decisive enterprise leadership. This leader must confidently engage in complex scientific and clinical discussions, synthesize insights across R&D, Access, and Commercial teams, and convert them into clear portfolio priorities and differentiated global strategies. With full accountability for value creation, the role requires strong P&L acumen and the ability to make disciplined trade‑offs that optimize lifecycle value, launch success, and long‑term portfolio performance.

The I&I and Rare Disease portfolio represents significant strategic value to realizing Pfizer's vision to achieve leadership via breakthroughs in prioritized diseases and biological axes to generate highly differentiated, multi-indication mega-blockbusters. Today, the portfolio delivers more than $10B globally with 22 ongoing clinical studies underway to significantly expand our product portfolio over the next several years.

Role Responsibilities

1. Long-Range Strategic Planning & Portfolio Management

• Develop and execute comprehensive long-range commercial and marketing strategies for I&I and Rare Disease portfolios, encompassing pipeline assets from early development to in-line assets through commercial maturity.
• Serve as single, authoritative commercial voice to R&D, Commercial Regions, and Business Development strengthening commercial input from early development through launch via participation in I&I Strategy Governance Team to influence clinical development plans and investment decisions.
• Lead development of business cases for new product launches and lifecycle management investments.

2. Launch Excellence & Commercialization Strategy

• Lead integrated global launch and marketing strategies coordinating cross-functional teams across R&D, Commercial Regions, Medical, Regulatory, Market Access, and Supply.
• Drive new product and indication launch readiness planning including market development activities, brand positioning, competitive assessments, and HCP/patient unmet need analysis.
• Own commercial asset lifecycle strategy for I&I and Rare Disease including implications of new indications and competitive dynamics

3. Commercial Excellence & Brand Strategy

• Raise the bar on marketing impact, quality, and brand performance by establishing consistently higher, impact-driven standards for strategic outputs and creative excellence
• Lead proactive market shaping in moments that matter, anticipating and addressing threats with pre-emptive strategies.
• Steer Commercial prioritization of evidence generation strategies across lifecycle and Regions to enable sharper cross-functional decisions and portfolio value maximization.

4. Cross-Functional Leadership & Governance

• Provide global strategic direction for in-line assets while enabling regional adaptation and tactical alignment.
• Own global brand strategy, launch plans, lifecycle management, and core content packages
• Partner with Global Access & Value (GAV) teams to develop pricing, contracting, and market access strategies that maximize global value of our portfolio.

5. Organizational Leadership & Talent Development

• Build and lead high-performing Global Commercial Strategy organization of 50+ highly engaged colleagues.
• Embed culture of cross-functional collaboration ensuring coordinated internal and external stakeholder engagement.
• Develop future commercial leaders with the capability to operate across full span of commercial development, launch, and in‑line commercialization.

Qualifications & Experience

Education

• Bachelor's degree in Life Sciences, Business, Marketing, or related field required
• MBA or other advanced degree (PhD, MD, PharmD) strongly preferred

Professional Experience

• Minimum 15+ years of successful, progressive marketing, commercial, and/or development experience in pharmaceutical or biotechnology industry
• Minimum 8-10 years in commercial leadership roles including Global/US/International marketing, commercial development/strategy
• Experience in both pipeline (pre-launch) and inline (post-launch) brand management spanning early development through commercialization

Therapeutic Area & Functional Expertise

• Brand management experience developing product strategies, positioning programs, and go-to-market plans
• Product launch experience including global launch planning and execution
• Portfolio management and strategic planning expertise across multiple therapeutic areas and development stages
• Demonstrated ability to influence complex development decisions and engage deeply in scientific dialogue.

Leadership & Organizational Capabilities

• Second-line leadership experience with accountability for developing and managing senior leaders
• Demonstrated ability to lead cross-functional teams and influencing without direct authority while managing complex stakeholder environments
• Track record of building and developing high-performing teams

Strategic & Business Acumen

• Strategic thinking and vision-setting capabilities with ability to translate into executable plans
• Financial and business acumen including forecasting, business case development, and investment prioritization
• Understanding of market access dynamics , payer strategies, and value demonstration
• Strong enterprise mindset, with proven P&L leadership capability and executive presence

Location

• New York, Collegeville, Cambridge; other global Pfizer Commercial locations considered on a case-by-case basis

Physical/Mental Requirements

• Comfort working in a fast-paced environment and making complex decisions quickly
• Ability to leverage AI models, synthesize and analyze complex data, and understand trends and mathematical calculations
• Ability to travel domestically and internationally as needed for congresses, sales meetings and customer interactions

Non-standard Work Schedule Travel or Environment Requirements

• Pending Pfizer policies, travel is required: Domestic or International travel of up to 25%

Other Job Details:
Last Day to Apply: May 31, 2026

Location : Selected Candidate must be onsite 2.5x weekly, travel to NYHQ & Cambridge on a regular basis.

The annual base salary for this position ranges from $313,100.00 to $521,900.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 35.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

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