Senior Director, Patient Reported Outcomes

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.

General Description:

The Senior Director, Patient Reported Outcomes (PRO), is a senior scientific and strategic leader accountable for developing and executing integrated evidence-generation strategies that demonstrate the humanistic value of BeOne Medicines therapies. The role provides enterprise-level PRO leadership across one or more assets, indications, therapeutic areas, or regions and ensures that high-priority evidence needs are represented in integrated evidence plans, medical strategies, clinical development plans, and value and access strategies. The Senior Director influences portfolio and asset decisions, leads complex global humanistic programs, governs scientific quality and investment, and builds organizational capability through people leadership, matrix leadership, and external scientific engagement.

Working across Clinical Development, Medical Affairs, Global Value, Access and Pricing, Biostatistics, Data Science, Patient-Reported Outcomes, Regulatory, Safety, Publications, Legal, Compliance, Privacy, and regional teams, the incumbent translates evidence gaps into prioritized, feasible research programs. The role is accountable for strategic alignment, scientific rigor, compliant execution, timely delivery, budget stewardship, and effective communication of PRO evidence to internal decision-makers and appropriate external stakeholders.

Essential Functions of the Job:

Strategy and Portfolio Leadership

• Own and provide senior leadership for global or regional PRO strategy across assigned assets, programs, therapeutic areas, or portfolios throughout the product lifecycle.
• Shape integrated evidence plans by identifying, prioritizing, and revisiting evidence gaps in collaboration with cross-functional leadership and evidence-generating functions.
• Ensure PRO perspectives are incorporated into asset strategy, clinical development plans, medical plans, lifecycle planning, launch preparation, reimbursement strategy, and annual operating and budget processes.
• Advise senior leaders and governance bodies on PRO evidence priorities, investment trade-offs, methodological options, feasibility, timing, and risk.
• Anticipate changes in healthcare systems, payer and health technology assessment expectations, data availability, methodological standards, and the competitive landscape, and translate those changes into strategic recommendations.

Scientific and Methodological Leadership

• Provide executive scientific oversight for PRO real-world evidence, observational research, comparative effectiveness and safety research, burden-of-illness studies, patient preference research, health economic models, indirect treatment comparisons, evidence syntheses, and value communication deliverables.
• Guide the selection and implementation of fit-for-purpose patient-reported outcome and other clinical outcome assessment strategies in partnership with PRO and Clinical Development experts.
• Ensure research questions, protocols, analysis plans, models, and interpretations are scientifically rigorous, reproducible, transparent, and aligned with intended decision needs.
• Provide senior review and approval, within delegated authority, of concepts, protocols, statistical analysis plans, technical reports, models, publications, and executive presentations.
• Sponsor innovation in PRO, analytical, and data-science methods while ensuring appropriate validation, governance, and business relevance.

Program Governance and Execution

• Lead a portfolio of complex, high-impact evidence-generation programs from concept through results dissemination and project closure.
• Set priorities, decision rights, milestones, quality expectations, and escalation pathways for internal teams and external research partners.
• Oversee project budgets, forecasts, contracts, vendor performance, timelines, risks, and resource allocation, and take timely corrective action when objectives are at risk.
• Ensure appropriate cross-functional review and compliance with applicable legal, ethical, privacy, safety, regulatory, publication, data-governance, and company requirements.
• Establish fit-for-purpose quality controls and independent technical review for complex analyses, models, and high-impact deliverables.
• Ensure balanced interpretation of findings, including uncertainty, missingness, bias, confounding, generalizability, sensitivity analyses, and study limitations.

Cross-Functional and Executive Influence

• Serve as the senior PRO partner to asset teams, medical and development leadership, access teams, governance committees, and regional stakeholders.
• Build alignment across functions and geographies when priorities, evidence needs, timelines, or methodological perspectives differ.
• Translate complex scientific and economic evidence into clear implications and recommendations for executive, clinical, payer, regulatory, and nontechnical audiences.
• Facilitate timely decisions by framing options, trade-offs, dependencies, risks, and recommended actions.
• Contribute to business development, due diligence, portfolio assessment, and external partnership evaluations, as assigned.
• Lead or oversee publication and scientific communication strategies for assigned PRO programs in partnership with Publications and cross-functional stakeholders.
• Represent BeOne Medicines at scientific congresses, professional associations, advisory forums, and other appropriate external engagements.
• Build credible relationships with researchers, clinicians, payers, health economists, patient organizations, and other external experts in accordance with company policies.
• Advance the company’s scientific reputation through high-quality research, peer-reviewed publications, presentations, and responsible methodological leadership.

People and Organizational Leadership

• Lead, coach, and develop direct reports and provide matrix leadership to cross-functional colleagues, contractors, and external research teams.
• Set clear objectives, provide actionable feedback, support development planning, and create an inclusive environment that promotes accountability, collaboration, and scientific challenge.
• Assess capability and capacity needs and recommend hiring, external support, training, tools, standards, and operating-model improvements.
• Promote consistent PRO practices, knowledge sharing, reusable resources, and continuous improvement across global and regional teams.
• Demonstrate sound judgment, integrity, financial stewardship, and accountability for decisions and commitments.

Supervisory Responsibilities

• Manages and develops one or more employees, as assigned, and provides senior functional direction to matrix teams, contractors, and external research partners.
• Accountable for goal setting, performance and development discussions, workload prioritization, succession and capability planning, and a respectful, inclusive team environment.

Education Required:

• Advanced degree in health economics, outcomes research, epidemiology, biostatistics, public health, psychometrics, pharmacy, medicine, or a related quantitative or clinical discipline, or equivalent education and relevant experience.

Required Qualifications:

• Advanced Degree (Masters, PhD, PharmD, PhD, MD) with 10 or more years of progressively responsible experience in PRO, RWE, outcomes research, epidemiology, market access evidence, medical affairs, clinical research, or a related field, including substantial biopharmaceutical or healthcare-sector experience.
• Demonstrated success defining and executing evidence strategies for complex assets, therapeutic areas, or portfolios in a global or multi-regional environment.
• Deep expertise in several relevant methods, including observational study design, causal inference, comparative effectiveness, economic modeling, indirect treatment comparisons, evidence synthesis, PRO/COA methods, patient preference research, or analysis of claims, electronic health records, registries, or clinical-trial data.
• Proven ability to influence senior leaders, governance bodies, and cross-functional teams without relying solely on formal authority.
• Demonstrated leadership of complex programs, budgets, vendors, risks, competing priorities, people, and matrix teams.
• Strong scientific communication record and excellent written, verbal, presentation, negotiation, and stakeholder-management skills.
• Working knowledge of applicable research, privacy, safety, publication, compliance, and data-governance expectations.

Preferred Qualifications:

• Doctoral degree in a relevant discipline.
• Significant oncology and hematology experience.
• Experience with health technology assessment, reimbursement, regulatory, or value communication strategies across major global markets.
• Demonstrated publication record and external scientific presence in PRO, epidemiology, health economics, or related methods.
• Experience establishing functional standards, governance, centers of excellence, or enterprise-wide evidence-generation capabilities.
• Experience with statistical or analytical software and critical review of code outputs, models, data specifications, tables, and figures.

Computer Skills:

• PC, including MS Office Suite and MS Teams.
• Proficiency with productivity, collaboration, presentation, project-management, and document-management platforms.
• Familiarity with analytical tools, real-world data sources, economic-modeling applications, literature-review platforms, or regulated content systems is preferred.

Travel:

• Approximately 25–30%, including domestic and international travel as business needs require.
• Ability to participate in meetings across time zones and respond flexibly to critical business needs.
• Ability to perform the essential functions of the role with or without reasonable accommodation.

Additional Position Information:

• Reports to the Vice President, Integrative Evidence Generation and Health Economics, Global Medical Affairs.
• Work location: Remote.
• People-manager role with direct reports and/or matrix leadership, as assigned.

Global Competencies

When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.

• Fosters Teamwork
• Provides and Solicits Honest and Actionable Feedback
• Self-Awareness
• Acts Inclusively
• Demonstrates Initiative
• Entrepreneurial Mindset
• Continuous Learning
• Embraces Change
• Results-Oriented
• Analytical Thinking/Data Analysis
• Financial Excellence
• Communicates with Clarity

Salary Range: $222,000.00 - $292,000.00 annually

BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness.

We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact View email address on aiapply.co.