Research Associate/Senior Research Associate, Cell Science

Research Associate Or Senior Research Associate – Cell Science

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials, SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.

We are seeking a Research Associate or Senior Research Associate – Cell Science to support cell line development through hands-on cell biology, CHO cell line development, and functional assay execution. This role is lab-based and requires deep experience with CHO cell culture and mammalian expression systems. You will work cross-functionally with Protein Engineering and Process Development teams to generate and characterize stable cell lines, support expression of antibody and multi-specific formats, and deliver high-quality data to advance pipeline programs. This role requires full-time onsite presence in our Redmond, WA office, with a planned relocation to our new Bothell, WA facility in fall 2026.

Key Responsibilities

• Maintain mammalian cell cultures
• Generate and maintain stable CHO cell lines for antibody expression
• Perform transfection, clone selection, single-cell cloning, and productivity screening
• Support cell banking activities and maintain detailed documentation
• Perform expression vector construction, plasmid preparation, and NGS sequencing

Data Analysis & Documentation

• Analyze and interpret experimental data
• Maintain accurate electronic lab notebook records
• Present findings clearly to cross-functional teams

Cross-Functional Collaboration

• Contribute to troubleshooting, assay development, and process improvements
• Operate effectively in a fast-paced, early-stage R&D environment

Qualifications

• BS or MS in Cell Biology, Molecular Biology, Biochemistry, or related field
• Research Associate I: 1+ years of industry experience in biologics or antibody discovery
• Senior Research Associate: 4+ years of industry experience in biologics or antibody discovery
• Strong background in mammalian cell biology and expression systems
• Demonstrated hands-on expertise in CHO cell culture and stable cell line development
• Ability to thrive in a fast-paced team environment and deliver complex objectives under tight deadlines
• Availability of working weekend and holiday shifts as needed

Required Technical Skills

• CHO suspension culture and clone screening
• Stable transfection methods
• Cell Biology and Molecular Biology laboratory skills
• Familiarity with antibody or multi-specific biologics preferred
• Strong experimental design and troubleshooting skills

Compensation and Benefits: The expected base salary range for this position is $60,000 - $85,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate's level qualifications, experience, and skills. While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role. SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE. SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.