Principal Applied Scientist
Siemens builds the systems the physical world runs on: factories, power grids, buildings, trains, hospitals. Industrial and physical AI is a major opportunity in applied AI, and one of the harder ones to get right. There is a generation of AI-powered products to build.
We are an applied science organization building the science behind them. The work sits at the intersection of machine learning research, real world data, and production systems running in industrial environments.
As Principal Applied Scientist, you lead the science on a major capability area inside the pod. You take ambiguous problems through hypothesis, method selection, experimentation, and into models that run in production. You are hands on with the modeling, and you are accountable for the rigor and the outcome.
This is a senior individual contributor role. You will work in close partnership with engineers and product managers who turn your work into product.
Key responsibilities
- Own one or more scientific capability areas end to end, for example perception, computer vision, language and agents, time series, control, planning, or evaluation
- Take problems from ambiguous product or system requirements through clear research questions, hypotheses, and success metrics
- Lead applied research projects: literature review, method selection, experimentation, ablation, error analysis, and productization
- Build and run the evaluation pipelines for the work you own: offline metrics, online experiments, robustness testing in industrial conditions
- Work with engineers to take models into production grade pipelines: data readiness, training infrastructure, inference, observability
- Make scientific tradeoffs in front of engineers and product managers, with evidence, and translate them into decisions the team can act on
- Identify and de-risk scaling challenges in your area: data quality, model drift, latency, throughput, cost, safety
- Raise the bar on experimentation rigor, reproducibility, and documentation across the team
- Apply responsible AI practices in your work: bias detection, model risk management, human in the loop controls
Basic qualifications
- 8+ years in applied machine learning, AI research, or data science, with models that shipped to production and made an impact
- Strong foundation in machine learning theory and practice across training, evaluation, and deployment
- Demonstrated experience taking research from a paper or prototype into a model that runs reliably in production
- Proficiency in Python and modern ML frameworks and toolchains
- Strong partnership track record with engineering teams on data, training infrastructure, and inference
- Clear written and verbal communication with engineers, product managers, and senior leaders
Preferred qualifications
- Experience applying ML in industrial or physical domains: manufacturing, automation, robotics, energy, mobility, infrastructure, healthcare
- Deep expertise in one of: multimodal ML, generative AI, retrieval augmented generation, agentic workflows, time series, control, or planning
- Scientific ML for physical systems: surrogate modeling, operator learning, physics-informed ML, geometry-aware ML, differentiable simulation, AI for semiconductor/EDA
- Hands-on experience building evaluation pipelines, running online experiments, or instrumenting production monitoring for a model you owned
- Publications, patents, open source contributions, or significant internal technology transfers
- Experience mentoring more junior scientists and engineers
- Experience working with globally distributed research, product, or engineering organizations
About the Team:
We are an early-stage engineering team solving hard technical problems at the intersection of AI, systems, and real-world interaction. We operate with high autonomy, collaborate closely across functions, and maintain high technical standards. Principal Engineers at our company are expected to lead by example, model engineering excellence, and shape both what we build and how we build it.
Our Commitment to Equity and Inclusion in our Diverse Global Workforce:
We value your unique identity and perspective. We are fully committed to providing equitable opportunities and building a workplace that reflects the diversity of society, while ensuring that we attract the best talent based on qualifications, skills, and experiences. We welcome you to bring your authentic self and transform the everyday with us.
$228.7k - $309.4k
We are looking for passionate, talented, and inventive Principal Applied Scientist with a strong machine learning background to help build industry-leading Conversational AI Systems. Our mission is to provide a delightful experience to Amazon’s customers by pushing the...PrincipalLocal areaFlexible hours$228.7k - $309.4k
...entertainment through cutting-edge AI? Prime Video’s technology teams are redefining the digital video experience at scale.As a Principal Applied Scientist at Prime Video, you will be a technical and strategic leader responsible for inventing, developing, and deploying...PrincipalTemporary workLocal areaFlexible hours$228.7k - $309.4k
AWS Agentic AI is looking for a Principal Applied Scientist who will partner with world-class scientists and engineers to pioneer the next generation of AI-driven development tools. Join the Amazon Kiro LLM-Training team and help create the most efficient coding agents...PrincipalLocal areaWorldwideFlexible hours$228.7k - $309.4k
We are looking for a Principal Applied Scientist to drive the research and development of real-time multimodal conversational AI. You will operate across two focus areas: advancing foundation models for speech and audio, and building the post-training systems (reward modeling...PrincipalLocal areaFlexible hours$126.2k - $264.1k
The IC4 Applied Scientist for Robotics, Perception, and Embodied AI will serve as a senior technical leader responsible for defining, prototyping, and delivering AI capabilities for commercially viable robotic systems. This role partners across science, software engineering...PrincipalTemporary workFlexible hoursShift work$206.3k - $388k
...understand intent and creative content. We're hiring a Principal Scientist to define how structured knowledge and foundation models work... ...listed as a hiring location, no specific application window applies, and the posting may close at any time based on hiring needs...PrincipalTemporary workLocal areaWorldwide$158.3k - $355.4k
...the scientific process (e.g., including modeling approaches, evaluation techniques, data collections).-Identifies opportunities to apply delivered solutions across product and/or business problems.Solution Development - Applied Research:-Ensures research proofs-of-concept...PrincipalTemporary workFlexible hoursShift work$276.1k - $350k
This is a Sr. Principal Applied Scientist role within the Advertising Full Funnel Agentic Intelligence and Models team, designed to drive foundational model innovation for Amazon Ads. The team is building next-generation agentic AI systems for advertising. This hire will...PrincipalLocal areaFlexible hours$179k
...pushing the boundaries of what's possible with AI, join us in shaping the future of advertising. Key job responsibilitiesThe Principal Applied Scientist in Advertiser Guidance team will lead 50+ builders in pioneering a new generation of agentic AI applications for Amazon...PrincipalLocal area$228.7k - $309.4k
As a Principal Applied Scientist for Full-Funnel Campaign optimization, you will invent the models that jointly allocate budget across sponsored ad products to maximize advertiser outcomes and long-term customer value.This is a rare charter to build foundational optimization...PrincipalLocal areaFlexible hoursDay shift$228.7k - $309.4k
...of Amazon's overall business strategy. You will be the Gen AI applied science leader that will determine what products and ads show... ...and translate it into actionable plans for our team of applied scientists and engineers.Key job responsibilitiesYou will play a pivotal...PrincipalLocal areaFlexible hours$276.1k - $350k
...process, including support for the interview or onboarding process, please visit for more information. If the country/region you’re applying in isn’t listed, please contact your Recruiting Partner.The base salary range for this position is listed below. Your Amazon...PrincipalLocal areaFlexible hours$224k
...loyalty and traveler satisfaction.We are looking for a Principal Machine Learning Scientist to join our growing Travel Search & Discovery team. This... ...domain is @expediagroup.com. The official place to find and apply for roles is .Equal OpportunityExpedia is committed to...PrincipalFull time$224k
...inform the team's technical directionMentor senior ML engineers and scientists, providing technical guidance on agentic design patterns, LLM... ...domain is @expediagroup.com. The official place to find and apply for roles is .Equal OpportunityExpedia is committed to creating...PrincipalFull timeWorldwide$192k - $304.75k
We are now looking for an Applied Deep Learning Research Scientist, Efficiency!Join our ADLR - Efficiency team to make deep learning faster and consume less energy! Our team influences the next-generation hardware to make AI more efficient; we work on the Nemotron series...Full time$192k - $304.75k
...with deep quantum computing domain expertise to path-find the future. As a Senior Quantum Error Correction Research Scientist for Quantum Computing Applied Research, you'll focus on technical pathfinding, helping to develop innovative technologies that advance the state...Full time$192k - $304.75k
...approach to accelerated computing. We're looking for a passionate scientist at the intersection of quantum device physics and advanced... ...help accelerate the entire quantum ecosystem. As a Sr. Quantum Applied Research Scientist, you will help design and build high-fidelity...Full timeRemote work$168k - $264.5k
...foundation models for life sciences. We are seeking senior research scientists and engineers to push the frontier of large-scale foundation... ...in the combination of modern machine learning techniques as applied to drug discovery, genomics, proteomics, or medical chemistry....Full time$192k - $304.75k
...approach to accelerated computing. We're looking for a passionate scientist at the intersection of quantum device physics, quantum... ...help accelerate the entire quantum ecosystem. As a Sr. Quantum Applied Research Scientist, you will help design and build real-time models...Full timeRemote work$192.2k - $260k
The Artificial General Intelligence (AGI) Customization Team is seeking a highly skilled and experienced Applied Scientist in the medical imaging domain foundation models. The role focuses on medical imaging domain to develop state-of-the-art services and tools for model...Local areaFlexible hours$192.2k - $260k
We are seeking a Sr. Applied Scientist to focus on Robot Navigation. In this role, you'll research and develop advanced navigation systems that enable robots to move reliably and safely through complex, dynamic environments. You'll work across a broad spectrum of navigation...Local areaFlexible hours$192.2k - $260k
The Foundational AI (FAI) team is looking for a passionate, talented, and inventive Applied Scientist with a strong deep learning background, to build industry-leading Generative Artificial Intelligence (GenAI) technology with Large Language Models (LLMs).Key job responsibilitiesAs...Local areaFlexible hours$184k - $287.5k
...support applications such as disease progression modeling, treatment response prediction, and precision medicine.You will join an applied research team that develops medical AI algorithms, foundation models, datasets, and workflows. Our work combines publication-quality...Full time$192.2k - $260k
...requires strong background in combinatorial optimization, algorithms, algorithm engineering, and data structures, particularly as it applies to vehicle routing and related problems. Familiarity with Data Science and Machine Learning techniques is a plus.You will also play...Local areaFlexible hours$224k - $356.5k
...work. Come join the team and see how you can make a lasting impact on the world.NVIDIA’s Curator team is seeking a Senior Applied Research Scientist with experience researching, developing, and deploying deep learning models at scale across a range of modalities. You’ll...Full timeWork at officeRemote workFlexible hours$192.2k - $260k
...technologists, you can decide where a career Prime Video Tech takes you!We are looking for a self-motivated, passionate and resourceful Applied Scientist to bring diverse perspectives, ideas, and skill-sets to make Prime Video even better for our customers. You will spend your...Local areaWorldwideFlexible hours$142.7k - $270.95k
...all. New ideas can come from anywhere in our organization, including from you. Adobe Firefly’s Applied Science & Machine Learning (ASML) group invites an Applied Scientist / Machine Learning Engineer passionate about post-training and distillation of large generative...Full timeTemporary workLocal areaWorldwide$192.2k - $260k
We're seeking a Senior Applied Scientist to pioneer sensor-based algorithms that power next-generation experiences across Amazon's device ecosystem, including Echo, Kindle, Fire TV, and Fire Tablets. Working with multidisciplinary teams of scientists and engineers, you'...Local areaWorldwideFlexible hours$192.2k - $260k
...creation and growth of countless new businesses, and is a positive force for good. Our customers bring problems that will give Applied Scientists like you endless opportunities to see your research have a positive and immediate impact in the world. You will have the...Local areaImmediate startWorldwideFlexible hours$192.2k - $260k
Amazon is looking for a passionate, talented, and inventive Applied Scientist with a strong machine learning background to help build industry-leading technology in generative AI and foundational models.As part of our AI team in Amazon AWS, you will work alongside internationally...Local areaWorldwideFlexible hours
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Principal Applied Scientist. Be the first to apply!
- molecular biology scientist Santa Clara, CA
- water quality scientist Santa Clara, CA
- machine learning scientist Santa Clara, CA
- image scientist Santa Clara, CA
- machine learning research scientist Santa Clara, CA
- materials scientist Santa Clara, CA
- health scientist Santa Clara, CA
- scientist Santa Clara, CA
- quality control scientist Santa Clara, CA
- scientist biology Santa Clara, CA

