Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior IT Architect (Enterprise Applications / Clinical Platforms)

$133.1k - $221.9k

McKesson

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve - we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow's health today, we want to hear from you.

Role Summary

Ontadais an oncology data science and technology business dedicated to transforming the fight against cancer. We specialize in real-world data and evidence generation that accelerates life science research, clinical technologies that support community providers with precise care, and provider engagement channels that enable education and insights.

We are hiring anIT Architect to define and drive cloud-native integration architecture acrossOntadaproducts and partner ecosystems. This role owns solution and platform architecture for API-led connectivity, event-driven integration, and secure data exchange-ensuring our systems are scalable, reliable, observable, and straightforward to evolve. Familiarity with healthcare interoperability standards (HL7/FHIR, including SMART on FHIR) is a plus for certain partner pathways, but the primary focus is strong enterprise-architecture fundamentals applied to modern cloud-native integration models.

Success in this role is measured by the clarity and adoption of your reference architectures and standards, the reliability and scalability of the integration ecosystem you enable, and your ability to influence decisions across multiple initiatives while mentoring and elevating engineering teams. Familiarity with AI/ML and NLP capabilities used in products (e.g., LLM-enabled workflows, retrieval patterns, evaluation, and governance) is a plus asOntadaexpands intelligentexperiences, butis not the core requirement.

Technical Environment

Cloud-Native Integration: API-led connectivity, event-driven architecture, pub/sub, schema management, idempotency, retries, backpressure
APIs: RESTful services,OpenAPI/Swagger, API gateways, versioning and contract-first design
Messaging: Kafka (or equivalent), queues/streams, event schema design
Platform Patterns: Microservices, containerization (Docker), service discovery, configuration management; service mesh (where applicable)
Data & Performance: Oracle and relational databases; Redis (caching); Elasticsearch; analytics/pipelines (e.g., Databricks)
Interoperability (nice to have): HL7v2, FHIR (R4+), SMART on FHIR, OAuth2/OIDC, C-CDA
Observability: Logging, metrics, distributed tracing (e.g., Dynatrace)
Cloud & Platforms: Azure, AWS, GCP, Cloud Foundry
Engineering Practices: CI/CD, automated testing, code reviews, architecture documentation

Key Responsibilities

Architecture Leadership & Strategy

  • Drive architecture for interoperability and integration capabilities across systems, services, and product offerings.

  • Partner with Product Owners, Sales, Business Analysts, Quality Assurance, and Project Management to translate functional and non-functional requirements into target architectures and delivery plans.

  • Define architecture standards, reference implementations, and guardrails for APIs, integration patterns, security, and operational readiness.

  • Evaluate solution options and drive alignment across stakeholders; communicate tradeoffs, risks, and recommendations to technical and non-technical audiences.

  • Providetechnical guidance to coach, motivate, and develop engineers and architects.

Cloud-Native Integration Architecture

  • Define and governintegrationreference architectures across APIs, events, and asynchronous workflows (request/response, pub/sub, choreography vs. orchestration).

  • Establish platform patterns and guardrails for API gateways, service-to-service communication, schema/version management, and contract testing.

  • Design for resiliency and performance using proven patterns (timeouts, retries, circuit breakers, bulkheads, idempotency, caching) andalignto SLOs/SLAs.

  • Guideevent-driven integration (e.g., Kafka or equivalent) with well-defined event schemas, lifecycle management, and operational controls.

  • Collaborate with security and platform teams to ensure secure-by-default integration approaches (OAuth2/OIDC, least privilege,secretsmanagement, threat modeling).

Healthcare Interoperability (Optional) & Partner Integrations

  • When applicable, drive design for healthcare data exchange leveraging HL7v2 and/or FHIR (R4+), including SMART on FHIR, to enable integrations with EMRs and partner systems.

  • Partner with domain SMEs and external stakeholders to define interoperability expectations (security, conformance, and onboarding) and ensure integrations are scalable and supportable.

  • Define API contracts, versioning strategy, and error taxonomy to enable predictable integrations for internal and external consumers.

  • Partner with engineering teams to implement and evolve reusable integration components, adapters, and accelerators that reduce time-to-integrate.

Operational Excellence & Production Ownership

  • Collaborate with engineering in release, sprint, and project planning to ensure delivery commitments are tracked and met across the SDLC.

  • Demonstrate strong architectural ownership in production operations to address customer needs for support, issue analysis, enhancements, and corrective actions.

  • Evolve software systems, infrastructure, and architecture to support growth, SLAs, availability, and continued operation.

  • Drive operational readiness practices including observability, runbooks, incident response, and post-incident improvements.

  • Resolve technical problems, issues, and escalations across delivery teams and project activities.

AI Enablement (Preferred)

  • Partner with product and engineering teams toidentifyand deliver AI-enabled capabilities, from discovery and design through deployment, monitoring, and continuous improvement.

  • Guide architecture patterns for integrating model services into cloud-native systems (APIs, events, data pipelines) withappropriate security, privacy, and compliance controls.

  • PromoteMLOps/LLMOpspractices (versioning, CI/CD, automated testing, observability, rollback) and responsible AI governance.

  • Collaborate on evaluation approaches to ensure AI features are reliable and safe for production use.

Minimum Requirement

Degree or equivalent and typically requires 7+ years of relevant experience.

Education

Bachelor's degree in computer science, Software Engineering, Information Systems, or equivalent practical experience.

Critical Skills

  • 7+ years of software engineering experience, including 4+ yearsinarchitecture (solution, platform, or enterprise) with ownership across multiple systems.

  • Strong enterprise integration architecture skills across REST APIs, event-driven messaging, and secure data exchange patterns.

  • Strong technical fundamentals in cloud-native architecture (microservices, containers, resiliency patterns, observability) on Azure, AWS, or GCP.

  • Experience designing andoperatinglarge-scale, multi-tenant services with reliability, scalability, and security best practices.

  • Ability to drive cross-functional technical decisions, mentor engineers/architects, and communicate clearly through documentation and design reviews.

  • Strong communicationand stakeholder-management skills, witha track recordof influencing cross-team decisions through documentation and design reviews.

  • Nice tohave:familiarity with HL7/FHIR and/or willingness to learn quickly as needed for partner integrations.

Preferred Skills

  • Optional/nice tohave:hands-on experience with FHIR (profiles, implementation guides, SMART on FHIR) and/or HL7v2, including conformance and integration testing.

  • Experience integrating with multiple EMRs and partner ecosystems; familiarity with common healthcare workflows and data exchange constraints.

  • Hands-on experience with microservices frameworks (e.g.,Springor equivalent) and API management practices.

  • Experience with messaging and integration platforms (Kafka, service bus/queues, stream processing) and caching technologies (e.g., Redis).

  • Experience with platform engineering patterns such as service mesh, policy-as-code, and automated architecture validation in CI/CD.

  • Experience with observability platforms (e.g., Dynatrace) and production operations best practices.

  • AI/ML product delivery experience (LLM-enabled workflows, evaluation, and responsible AI governance).

  • Experience with Elasticsearch and/or analytics platforms (e.g., Databricks).

What Success Looks Like

At 6 Months

  • You haveestablishedand socialized a target-state cloud-native integration architecture, with clear standards for APIs, events, resiliency, and security.

  • You have delivered at least one end-to-end initiative (design through production) for a key integration capability (e.g., event streaming, API modernization, partner onboarding accelerator).

  • Teams are adopting your reference patterns and documentation with reduced integration friction and faster delivery.

  • You are actively supporting production operations through improved observability, incident learnings, and reliability improvements.

At 12 Months

  • You own and continuously improve the integration architecture across multiple products and partner pathways, with measurable gains in reliability, scalability, and onboarding speed.

  • You have matured governance forintegrationassets (API standards, event schemas, implementation guides where applicable, and conformance testing) and created a repeatable delivery playbook across the SDLC.

  • You are a trusted technical leader influencing roadmaps, investment decisions, and cross-team alignment.

  • You have helped teams incorporate intelligent capabilities responsibly (where applicable) through clear evaluation, monitoring, and risk controls.

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, pleaseclick here.

Our Base Pay Range for this position

$133,100 - $221,900

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson's (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:

McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.


McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: careers.mckesson.com.

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson's full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) View email address on click.appcast.io or (Canada) View email address on click.appcast.io. Resumes or CVs submitted to this email box will not be accepted.

Join us at McKesson!

Vacancy posted 1 day ago
Similar jobs that could be interesting for youBased on the Senior IT Architect (Enterprise Applications / Clinical Platforms) in Irving, TX vacancy
  •  ...Description Summary: The IT Architect II is responsible for...  ..., system security, application architecture,...  ...management. Provides enterprise architectural framework...  ...to evaluate planned platform growth, increasingly...  ...understanding of assigned clinical/business operations,... 
    Platform
    Application
    Full time
    Work at office
    Local area
    Flexible hours
    Shift work

    Christus Health

    Irving, TX
    17 hours ago
  •  ...About the Role We are seeking a Senior AI Architect - Enterprise Integrations to join our growing AI...  ...systems including CRMs, ERPs, data platforms, and third-party APIs Establish...  ...Experience ~8+ years of experience in application or solution architecture, with at... 
    Platform
    Application
    Senior
    Worldwide

    IBM

    Dallas, TX
    7 days ago
  • $150k

     ...Senior IT Architect Locations: Atlanta | Austin | Boston | Brooklyn | Chicago | Dallas |...  ...Cybersecurity, Digital Transformation, Enterprise Application and Risk functions. We balance...  ...transforming strategies into leading-edge tech platforms, at scale. Senior IT Architects... 
    Platform
    Application
    Senior
    Work at office

    Boston Consulting Group

    Dallas, TX
    3 days ago
  • $93k - $189k

    Description As a Senior IT Business Architect , you will play a critical role in...  ...business capabilities with enterprise goals. You will serve as a...  ...will be pivotal in driving application modernization , digital...  ...strategies, and adoption of modern platforms (e.g., microservices, APIs... 
    Platform
    Application
    Senior
    Work at office

    Huntington Bancshares, Inc.

    Dallas, TX
    17 hours ago
  • Ernst & Young Oman is hiring a Senior ServiceNow Developer in Dallas to drive enterprise-scale transformations. The candidate...  ...solutions on the ServiceNow platform, ensuring scalability and high...  ...include custom application development, mentoring team members... 
    Platform
    Application
    Senior
    Flexible hours

    Ernst & Young Oman

    Dallas, TX
    1 day ago
  • $250k - $290k

     ...Technology - Health – Enterprise Architect – Senior Director The...  ...focusing on Health IT, you will lead high-...  ...optimize enterprise IT platforms and optimize...  ...emerging technologies (Clinical and revenue cycle management...  ...-office and admin application platforms... 
    Platform
    Application
    Senior
    Work experience placement
    Summer holiday
    Work at office
    Flexible hours

    EY

    Dallas, TX
    1 day ago
  •  ...: operating systems, database systems, applications, and other technologies. Troubleshoots...  ...vulnerabilities in relation to the enterprise environment. Assists with responses...  ...Support M365 services relevant to Windows platforms, including OneDrive integration Mentor... 
    Platform
    Application
    Senior
    Work at office
    Weekend work

    Talent Groups

    Dallas, TX
    3 days ago
  •  ...WHAT YOU WILL DO As a Senior Architect at Credera, you will...  ...to date on the latest application development...  ...middle tier, and database platforms You are well-versed in...  ...volume, mission-critical enterprise solutions that are...  ...software engineering; it's a powerful accelerator... 
    Platform
    Application
    Senior
    H1b
    Remote work
    Worldwide
    Flexible hours
    2 days per week

    Cedera

    Dallas, TX
    2 days ago
  • Ardurra is hiring a Solutions Architect for its Enterprise Applications team in Dallas, TX. This role involves defining the architecture across the company...  ...applications and strong skills in integration platforms and data architecture. Ardurra promotes a family-like... 
    Platform
    Application
    Senior
    Remote job

    Ardurra

    Dallas, TX
    1 day ago
  •  ...Position Summary Senior Software Full Stack Engineer...  ...Software Engineers, Architects, Engineering Managers,...  ...every phase of the application development lifecycle...  ...comprehensive knowledge of enterprise data flow. Key...  ...the Senior Manager of Clinical Software Engineering,... 
    Application
    Senior
    Flexible hours
    Afternoon shift

    Caris Life Sciences

    Irving, TX
    2 days ago
  •  ...Job Description Summary: The Cloud Platform Engineer is responsible for designing, engineering, and operating enterprise compute platforms across a hybrid environment...  ...management. Partner with middleware, application, and DevOps teams to align infrastructure... 
    Platform
    Application
    Work at office

    ADT

    Irving, TX
    17 hours ago
  •  ...Summary: The Windows Platform Engineer is...  ...engineering, and operating enterprise Windows-based compute...  ...enterprise compute, and application hosting platforms....  ...cloud-to-cloud). Architect and support Active Directory...  ...skills across IT engineering domains.... 
    Platform
    Application
    Work at office

    ADT

    Irving, TX
    1 day ago
  • $80.46k - $142.72k

     ...GIS Senior Analyst Arcadis is the world...  ...MSSQL, Postgres) and enterprise Geographic...  ...mobile solutions, web applications, and visualization tools and cloud platforms. This role will...  ...and SQL Server. Architect workflows and processes...  ...Computer Science, IT, Environmental... 
    Platform
    Application
    Senior
    Full time
    Part time
    Flexible hours

    ARCADIS

    Dallas, TX
    3 days ago
  •  ...using Cisco technologies, architecting high availability and redundancy...  ...to support Tier 0/1 applications and improve security posture...  ...and routers (Nexus, Catalyst platforms). Design Layer 2 and Layer...  ..., and throughput across enterprise environments. Lead capacity... 
    Platform
    Application
    Senior

    Prophecy Technologies

    Irving, TX
    1 day ago
  • $158.3k - $263.9k

     ...from you. The Enterprise Architect Lead, Digital Solutions...  ...partners closely with senior leaders, business stakeholders, clinical teams, and technology...  ...digital initiatives and platforms. Advise senior...  ...be compliant with any applicable regulations. In addition... 
    Platform
    Application
    Remote work

    McKesson

    Irving, TX
    17 hours ago
  • $125k - $153k

     ...Hybrid Oppty! Join our Data Platform & Analytics team as a Sr...  ...Sick Leave Job Details Senior Business Analyst - Enterprise Data & Analytics (...  ...meetings with developers, architects, and business stakeholders...  ...Scrum Master, PMI-PBA) Application Interested in hearing more... 
    Platform
    Application
    Senior
    Work experience placement
    Local area

    Jobot Consulting

    Coppell, TX
    17 hours ago
  •  ...Systems Engineer - III/Sr BI Developer/Architect America Networks is a leading sensor...  ...solution and push the data on the best cloud platform to fit your needs, including your own....  ...business processes and transform into application level requirements; Ability to make... 
    Platform
    Application
    Senior
    Work experience placement

    America Networks

    Irving, TX
    3 days ago
  • $102.4k - $179k

     ...data integration platforms, and DevOps practices...  ...high-performing applications. You will...  ...continuous evolution of enterprise technology...  ...product owners, architects, analysts, and engineering...  ...accelerate their clinical and operational...  ...home health and senior living Apexus - The... 
    Platform
    Application
    Senior
    Full time
    For contractors

    Vizient

    Irving, TX
    4 days ago
  • $64 - $67 per hour

     ...Senior Java Developer Global Financial Firm located...  ...Utilize knowledge of applications development...  ...experience developing and architecting integrated solutions...  ...MSSQL, Oracle) or NoSQL platforms. ~ Ability and...  ...understanding of Standard, Enterprise Design Patterns, and... 
    Platform
    Application
    Senior
    Contract work
    Immediate start

    Axelon

    Irving, TX
    2 days ago
  •  ...Enterprise Engineer I Job Category: Administrative Requisition Number: ENTER002271...  ...operations across hybrid infrastructure platforms, including Azure, VMware, and Hyper-V....  ...troubleshooting skills across WinRM, GPO/application of policy, networking, and virtualization... 
    Platform
    Application
    Full time
    Work at office
    Flexible hours

    TAMKO

    Irving, TX
    17 hours ago
  •  ...Senior Java developer Location: Plano TX, Pennington,...  ...Good exposure to Angular application development. Min. 5 years...  ...Hands on experience in Enterprise Integration Patterns (EIP);...  ...development through global platforms & local academy. Career... 
    Platform
    Application
    Senior
    Full time
    Local area

    SARIAN Co

    Irving, TX
    3 days ago
  •  ...Senior Network Engineer As a Senior Network...  ..., service-based enterprise environment, we'd...  ...cloud security, and platform teams to ensure...  ...security groups, Web Application Firewalls (AWS WAF...  ...(AWS Solutions Architect/Advanced Networking...  ...AI/ML to enhance IT operations and client... 
    Platform
    Application
    Senior

    MSLGROUP

    Irving, TX
    17 hours ago
  •  ...Job Title: Senior Software Developer - Dynamics Location: Irving, TX - 3 days hybrid Position...  ...end-to-end CRM solutions, integrating with enterprise applications, and optimizing business processes through the Power Platform. The ideal candidate has strong... 
    Platform
    Application
    Senior

    Jobs via Dice

    Irving, TX
    2 days ago
  •  ...Center Technician III is primarily a senior server administrator with project...  .... Administer and support enterprise server environments. Lead troubleshooting...  ...monitoring and observability platforms. Own assigned systems, applications, or operational responsibilities.... 
    Platform
    Application
    Senior

    NeerInfo Solutions

    Irving, TX
    1 day ago
  •  ...among the leaders in areas like application development and AI/ML, and...  ...We are looking for a Senior Application Security Engineer...  ...Native Application Protection Platforms ( CNAPP ) such as Wiz ;...  ...clients, including Fortune 500 enterprises and leading product brands.... 
    Platform
    Application
    Senior
    Flexible hours

    AgileEngine

    Irving, TX
    3 days ago
  •  ...Engineer We are seeking a highly skilled Senior Java Engineer to design, develop, and maintain scalable, high-performance enterprise applications. The ideal candidate will have deep...  ...architecture Exposure to cloud platforms (AWS, Azure, or GCP) Experience with... 
    Platform
    Application
    Senior

    Virtusa

    Irving, TX
    1 day ago
  • $43.59 - $51.59 per hour

     ...Genesis10 is currently seeking a Senior Information Security...  ...with a strong foundation in enterprise firewall technologies, particularly...  ...cloud, infrastructure, and application teams) to integrate security...  ...enterprise-grade firewall platforms and secure network... 
    Platform
    Application
    Senior
    Hourly pay
    Permanent employment
    Contract work
    Work experience placement

    Genesis10

    Irving, TX
    1 day ago
  •  ...cluster, memory management) Experience working with enterprise technology platforms. Possess a strong technical background Strong experience...  ...to a wide range of technologies including enterprise application integration, database design and configuration, web... 
    Platform
    Application
    Senior
    Contract work

    Anagh Technology

    Irving, TX
    3 days ago
  • $101k - $120k

     ...total talent solutions companies? It takes trailblazers, innovators, and...  ...Diego, CA - 3 days a week onsite A Senior Specialist, Enterprise IT Applications is an advanced technology role focused...  ..., or custom-built in house platforms. Professionals in this function bridge... 
    Platform
    Application
    Senior
    Full time
    Work experience placement
    Work at office
    Home office
    3 days per week

    AMN Healthcare

    Dallas, TX
    4 days ago
  • $203.75k - $280.16k

     ...Transforming the Future of Enterprise Planning At o9, our mission...  ...be the Most Value-Creating Platform for enterprises by...  ...optimize their supply chains. Senior AI Architect o9 is restructuring...  ...Explore the practical application of this paradigm in Davos Insights... 
    Platform
    Application
    Senior
    Shift work

    o9 Solutions

    Dallas, TX
    17 hours ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior IT Architect (Enterprise Applications / Clinical Platforms). Be the first to apply!