Pharmaceutical Scientist (R2-R4)

Eli Lilly and Company seeks a Pharmaceutical Scientist (R2-R4) to develop nucleic acid-based formulations for therapeutic candidates. Design, implement, and troubleshoot laboratory experiments for lipid nanoparticle (LNP) formulations from small scale to mid-scale. Perform daily characterization of LNPs, assessing stability using particle sizing, Ribogreen assay, and osmometry. Optimize current formulation methods and processes for delivery of nucleic acids. Screen optimal process to enable midscale production which supports large animal studies. Develop comprehensive standard operating procedures (SOPs) and generate test method documentation. Interpret and analyze data and maintain comprehensive records of multiple laboratory projects. Support downstream processing of nucleic acid-based formulations. Position requires a Master’s degree in Chemistry, Pharmaceutical Science, or a related scientific field, and 1 year of experience with researching nucleic acid formulation and characterization or 1 year of experience with polymeric nanoparticles formulation and characterization. Experience must include a minimum of: 1 year of experience with analytical techniques for characterizing nanoparticles, including Dynamic Light scattering, Zeta potential, and Ribogreen; 1 year of experience with preparation of nanoparticle-based formulations at scales sufficient to support in vitro and in vivo studies; 1 year of experience with wet lab biology techniques; 1 year of experience with designing formulation methods, composition, and process parameters. Up to 10% domestic and international travel required. Job location: Boston, MA Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $101,026.00 - $122,845.00 per year Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities). Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. #J-18808-Ljbffr Lilly