Manager, Accounting

About SpyGlass Pharma: At SpyGlass Pharma (NASDAQ: SGP), we are focused on improving and preserving the vision of patients living with chronic eye diseases, while minimizing the burden treatment can place on their daily lives. We are advancing innovative long-term ophthalmic drug delivery technologies designed to provide sustained therapy through cataract surgery and help improve patient outcomes. We have built a highly collaborative team with deep expertise across ophthalmology, drug delivery, pharmaceuticals, and medical devices. Our scientists, engineers, and clinical leaders bring decades of experience developing and commercializing breakthrough technologies, united by a shared commitment to patients and our guiding principle: “We create for patients.” That mindset shapes how we build our products, our teams, and our culture. Backed by strong clinical progress, significant funding, and a growing organization, SpyGlass Pharma is entering an exciting stage of growth as we advance our lead program, the SpyGlass BIM-IOL, through Phase 3 clinical development. Summary: We are seeking an Accounting Manager to join our growing Finance & Accounting team at SpyGlass Pharma. Reporting to the Assistant Controller, this role will be responsible for managing core accounting functions, including payroll, general ledger maintenance, accounts payable/receivable, month-end close, and budget oversight. As SpyGlass scales, this position will play a key role in refining financial processes to support growth. This is a high-impact, hands-on role in a pre-revenue, R&D-focused environment, ideal for someone who thrives in fast-paced startups and is excited about working in a dynamic, evolving finance function. Essential Duties & Responsibilities: Oversee payroll administration, ensuring accurate and timely payroll processing, compliance with tax regulations, and benefits accounting. Oversee and manage travel & entertainment program administration including employee expense reporting, approval, and reimbursement. Manage day-to-day accounting operations, including general ledger maintenance, reconciliations, and financial statement preparation. Lead the month-end and year-end close processes, including journal entries, accruals, and financial reporting. Oversee accounts payable, accounts receivable, and cash management, ensuring efficient processes for vendor payments and expense tracking. Maintain and refine internal controls, accounting policies, and procedures to ensure compliance and scalability. Assist with budgeting, forecasting, and financial modeling, partnering closely with the VP of Finance. Prepare financial reports and investor updates, supporting fundraising and equity-related accounting. Support audit and tax compliance, including coordination with external auditors and tax advisors. Implement and optimize financial systems and automation tools to improve efficiency. Qualifications Required For Position: Bachelor’s degree in Accounting, Finance, or a related field; CPA preferred. 5-8+ years of accounting experience, ideally in startups, biotech, or life sciences. Strong understanding of GAAP, payroll processing, and pre-revenue financial reporting. Experience with venture-backed startups, investor reporting, and fund tracking is a plus. Public company experience related to supporting audits, SOX compliance and internal controls preferred. Hands-on experience with AP, AR, payroll, tax compliance, and financial statement preparation. Familiarity with stock-based compensation and equity accounting. Proficiency with NetSuite, QuickBooks, or other accounting software. Advanced Microsoft Excel skills Strong analytical and problem-solving skills, with the ability to work independently in a fast-moving environment. Excellent communication and collaboration skills, with a proactive and adaptable mindset. Why SpyGlass Pharma? We are offering a range of $140,000 - $160,000 based on experience and qualifications, along with an Annual Bonus opportunity. Share in our success with stock options, giving you a stake in the company’s future. Comprehensive health, dental, and vision insurance plans to keep you and your family healthy and happy, with a variety of plan and coverage options. Generous paid time off, including holidays, vacation days, and personal leave. SpyGlass Pharma is an Equal Opportunity Employer and participates in E-Verify. SpyGlass Pharma takes pride in maintaining a diverse environment and our policies are not to discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity, marital or veteran status, disability, or any other legally protected status. SpyGlass Pharma is also committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an email to View email address on click.appcast.io and let us know the nature of your request and your contact information. #J-18808-Ljbffr