Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Head of Core AI [Remote]

Full-time

psi

Boston, MA
  • Remote job

Overview

Physical Superintelligence is a startup with roots at Google, NVIDIA, Harvard, Meta, MIT, Oxford, Johns Hopkins, Cambridge, and the Perimeter Institute building AI systems to discover new physics at scale.

Our mission is to discover and commercialize transformative physics breakthroughs at scale with artificial superintelligence, safely, verifiably, and for broad public benefit.

The last century's golden age of physics gave us transistors, lasers, and nuclear energy. We believe artificial superintelligence will unlock the next one. We're creating the infrastructure to industrialize scientific discovery and usher in this new era.

We have one product: new physics, at scale.

Role

We are seeking a Head of Core AI to lead Core AI: the team that builds the models, agents, and training systems that do physics. This is applied work in service of a product. Everything Core AI builds exists to make PSI's AI-for-physics capability better.

Responsibilities

  • Lead Core AI, the organization that builds the models, agents and training systems that do physics: own the people, the delivery and the hiring.

  • Set the roadmap and own the research portfolio against one goal, making PSI's AI systems better at real physics: set direction, kill weak lines, double down on what works.

  • Hold the work to one bar, physics a real physicist would trust, and own the training and evaluation infrastructure the company depends on to get there.

  • Partner with Applied AI, which turns Core AI's work into products, and Physics, which supplies the problems and the verification; build on the platform Engineering runs.

  • Stay technical: carry individual work, review code, and set the bar in person.

What We're Looking For

  • Eight or more years of AI research work and a track record of leading AI research teams that shipped: you have run an industrial AI research group at a frontier lab, a fast-moving AI company, or equivalent, and the work made it into production systems or into results the field recognizes. At least three years of direct people management: hiring, performance reviews, and career development for the people who reported to you.

  • Research vision on a portfolio. You pick the question and design the experiment that settles it, state the result that would kill a line and stop it when that result arrives, know when a benchmark is being gamed, and trade elegance for something that ships this quarter.

  • Deep fluency across modern ML, with depth in one of the following and a working floor on the rest. You have personally built and trained systems that beat non-trivial baselines, and you can still do so.

    • Reinforcement learning and post-training: policy optimization, reward design, RLHF, RLVR, GRPO, RL for language models and for control.

    • Agents, evaluation and verification: tool use, long-horizon reasoning, memory and harnesses, evals, verifiers, reward models, instrumentation that separates reasoning from gaming.

    • Model architectures and training methods: transformers, state-space and graph models, neural operator and surrogate architectures for physical fields and meshes, scaling laws, optimization, training dynamics.

    • Scientific and generative modeling: learning from simulators, physics-informed and conservation-aware models, out-of-distribution behaviour, diffusion and generative models, code generation with checkable results.

Motivation for this specific job is assessed at the first conversation: why this over a frontier lab.

Nice to Have

  • Publications and standing at top ML venues, or an AI research artifact the community has adopted.

  • Enough physics or mathematics to hold a substantive conversation with domain scientists.

  • Hands-on experience applying agents or RL to science, mathematics, code, or other complex-reasoning domains.

  • Experience scaling an AI research organization through rapid growth: hiring, leveling, performance management.

  • AI-for-science experience: simulators, verification, scientific tool use.

How We Work

We hold a high technical bar and give people full ownership of their work, from spec to ship to on-call. We write contracts before logic, test against real systems instead of mocks, and favor simple designs that ship over clever ones that do not. Our development process is AI-native: we work with agentic coding tools daily, write specs that are legible to humans and agents alike, and lead with leverage.

Location and Compensation

This role is hybrid, three days a week in person in our Cambridge, MA office. We offer competitive compensation including salary, benefits, and meaningful early-stage equity. We evaluate on AI research judgment, technical depth, leadership track record, and shipping velocity. We are an equal opportunity employer and value diverse perspectives in building platforms for AI-driven discovery.

Work Authorization: Candidates must be authorized to work in the United States. PSI is not able to sponsor or take over sponsorship of employment visas for this role, now or in the future.

Export Controls. PSI's work involves technology that may be subject to U.S. export control laws. To comply with those laws, PSI may require that the person in this role be a U.S. person, meaning a U.S. citizen or national, a lawful permanent resident, or an individual granted refugee or asylum status in the United States, or be eligible to receive any required U.S. government export authorization. PSI will confirm eligibility with each candidate in the same way, and only to the extent export control laws require.

Equal Opportunity. PSI is an equal opportunity employer and does not discriminate on the basis of citizenship status, national origin, or any other characteristic protected by law.

Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the Head of Core AI [Remote] in Boston, MA vacancy
  •  ...Head of AI About the Company AI-native fintech building document intelligence SaaS for private market investors Industry Financial Services Type Privately Held, VC-backed About the Role The Company is seeking a Head of AI to lead its AI function... 
    Suggested

    Confidential

    Boston, MA
    4 days ago
  •  ...Head of Applied AI About the Company Innovative telehealth platform specializing in no-code software for DTC telehealth businesses Industry Internet Type Privately Held Founded 2021 Employees 51-200 About the Role The Company is seeking... 
    Suggested

    Confidential

    Boston, MA
    3 days ago
  • $175k - $250k

     ...Head of Government & Defense At WHOOP, we're on a mission to unlock human performance and healthspan. WHOOP empowers members to perform...  ..., and consistent pay practices that reflect our mission and core values. At WHOOP, we view total compensation as the combination... 
    Suggested
    Full time
    Work at office
    Local area
    Relocation

    Venturefizz Product Management Community

    Boston, MA
    3 days ago
  • $272.2k

     ...The Role: Moderna is seeking an enterprise-minded Head of Translational Medicine to lead and integrate translational medicine, translational...  ...and regulatory success. This is a senior leadership role at the core of Moderna’s ability to translate its mRNA platform into... 
    Suggested
    Permanent employment
    Full time
    Work at office
    Work from home

    Moderna

    Cambridge, MA
    10 days ago
  •  ...Alamos National Laboratory, and the Perimeter Institute building AI systems to discover new physics at scale. Our mission is to discover...  .... Close the loop between simulation and hardware: work with Core AI and Applied AI so that models are checked against real... 
    Suggested
    Permanent employment
    Full time
    Work at office
    Remote work
    3 days per week

    psi

    Boston, MA
    2 days ago
  •  ...will create a fully automated, closed loop, AI-integrated, drug discovery platform. As part of this build, we are seeking a Head of Small Molecule In Vitro Pharmacology. This...  ...with Takeda’s enterprise R&D priorities. Core responsibilities ~ Global strategy for in... 

    Takeda Pharmaceutical

    Boston, MA
    2 days ago
  • ## Head of Drug Substance & Analytical DevelopmentApplylocations: Cambridgetime type: Full...  ...this culture.Making bonds is at the core of everything we do. From discovering and...  ...platform that leverages advanced data-driven and AI/ML approaches, Zealand Pharma aims to lead... 
    Local area
    Immediate start

    Zealand Pharma

    Cambridge, MA
    4 days ago
  • $389.59k

     ...life-threatening diseases. Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you...  ...possibilities of what we can do together. How You Will Achieve More:The Head of Medical Affairs, reporting to the EVP, Chief Medical Officer,... 
    Full time
    Local area
    Shift work

    Intellia Therapeutics

    Cambridge, MA
    3 days ago
  • $100 per hour

    Director, Head of Incentive Compensation & Execution Excellence United Sates, Cambridge, MA Overview: The Director of Sales Execution...  ...deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency... 
    Full time
    Contract work
    Temporary work
    For contractors
    Work at office
    Local area
    Flexible hours
    Night shift

    Alnylam Pharmaceuticals, Inc.

    Cambridge, MA
    5 days ago
  • $155.37k - $255.26k

    The Head of Operational Excellence and Enablement will drive strategic initiatives to enhance...  ...and continuous improvement as a core mindset across the underwriting organization...  ...Guardian may use artificial intelligence tools (“AI Tools") to automate the sorting and... 
    Full time
    H1b
    Work at office
    Remote work
    Visa sponsorship
    Work visa
    Flexible hours
    3 days per week

    Guardian Life Insurance

    Boston, MA
    1 day ago
  • $212k - $333.19k

     ...will create a fully automated, closed loop, AI-integrated, drug discovery platform. As part of this build, we are seeking a Head of Small Molecule In Vitro Pharmacology. This...  ...alignment with Takeda’s enterprise R&D priorities.Core responsibilitiesGlobal strategy for in vitro... 
    Minimum wage
    Local area
    Remote work

    Takeda

    Boston, MA
    3 days ago
  • $212k - $333.19k

     ...company that will inspire you and empower you to shine? Join us as a Head of Characterization Small Molecules in our Cambridge office.At...  ...through publications, conferences, and thought leadership.CORE ELEMENTS RELATED TO THIS ROLE:Set enterprise strategy for extended... 
    Minimum wage
    Work at office
    Local area
    Remote work

    Takeda

    Boston, MA
    2 days ago
  •  ...product lifecycle and the patient’s journey. Purpose: Reporting to the Global Head of Neuroscience Pipeline, this role provides strategic medical and scientific leadership for core medical affairs activities in AbbVie’s Neuroimmunology Pipeline Portfolio. This includes... 
    Full time
    Local area
    3 days per week

    AbbVie Inc.

    Boston, MA
    a month ago
  •  ...Head of Investor Relations, Credit Fund About the Company Globally-recognized provider of billing, distribution, & marketing solutions...  ...similar areas. An established network of LP relationships is a core requirement, and direct experience with private credit or first-... 
    Local area

    Confidential

    Boston, MA
    1 day ago
  • $59.54k - $66.76k

    The Opportunity Lesley University is seeking a Head Coach of Men’s & Women’s Cross Country/Track & Field; Academic Liaison (Head Coach)...  ...Equal Opportunity. Base Pay Range $59,536 - $66,761 annually At our core, we are a caring and compassionate community bound together by... 
    Work at office
    Night shift
    Weekend work

    Lesley University

    Cambridge, MA
    4 days ago
  •  ...Head of Acquisition About the Company Innovative tech company focusing on cryptocurrency portfolios Industry Financial Services...  ...data, managing external agencies and partners, and using AI tools to accelerate research, creative development, analysis, and... 

    Confidential

    Boston, MA
    3 days ago
  •  ...Head of US Government Affairs About the Company Top developer of anti-money laundering software for Bitcoin-run businesses Industry Computer Software Type Privately Held, VC-backed Founded 2014 Employees 501-1000 Funding $200+ million... 

    Confidential

    Boston, MA
    3 days ago
  •  ...Head of Structures About the Company Building an orbital-class launch vehicle designed for reuse Industry Defense & Space Type Privately Held, VC-backed About the Role The Company is seeking a Head of Structures to take on a pivotal role in the... 

    Confidential

    Boston, MA
    3 days ago
  •  ...Head of Privacy About the Company Innovative organization designing, engineering, & selling home security equipment Industry...  ...also guide contract negotiations involving personal data, support AI governance, and lead legal analysis of notification obligations related... 
    Contract work

    Confidential

    Boston, MA
    3 days ago
  •  ...Global Head of Channel About the Company Innovative cybersecurity company specializing in malware analysis & threat detection solutions Industry Computer & Network Security Type Privately Held, VC-backed Founded 2013 Employees 51-200 Funding... 

    Confidential

    Boston, MA
    1 day ago
  •  ...Head of Marketplace About the Company Special Operations-inspired cognitive performance coaching for law enforcement professionals Industry Professional Training & Coaching Type Privately Held, VC-backed Founded 2023 Employees 11-50 Funding... 

    Confidential

    Boston, MA
    1 day ago
  •  ...Head of Dynamics 365 About the Company Established API CDMO operating in a validated, GxP manufacturing environment Industry...  ...reporting frameworks, and analytics, and familiar with applying AI in ERP and analytics contexts. Experience with warehouse devices... 

    Confidential

    Boston, MA
    2 days ago
  •  ...Head of Funnel Conversion About the Company Innovative provider of weight loss & health products Industry Information Technology...  ...role in its mission to become the world's first full-stack AI doctor. The successful candidate will be responsible for the end-... 
    Full time
    Remote work

    Confidential

    Boston, MA
    1 day ago
  •  ...Head of Actuarial About the Company Health insurer seeking actuarial leader to drive strategy, modeling, and C-suite insights. Industry Insurance Type Privately Held About the Role The Company is seeking a Head of Actuarial to play a pivotal role... 

    Confidential

    Boston, MA
    3 days ago
  •  ...Head of Credit & Fraud About the Company Expanding financial technology (FinTech) & wealth management platform Industry Internet Type Privately Held, VC-backed Founded 2009 Employees 51-200 Funding $101-$200 million Categories Internet... 

    Confidential

    Boston, MA
    1 day ago
  •  ...Head of Channel About the Company Innovative provider of AI security solutions Industry Computer & Network Security Type Privately Held, VC-backed Founded 2022 Employees 51-200 Specialties security for ai cyber security gen ai security... 

    Confidential

    Boston, MA
    1 day ago
  •  ...Head of Treasury & Capital Management About the Company Life and annuity insurer focused on treasury, capital management, and strategic growth Industry Insurance Type Privately Held About the Role The Company is seeking a Head of Treasury & Capital... 

    Confidential

    Boston, MA
    3 days ago
  •  ...Head of Dynamics 365 About the Company Established API contract development and manufacturing organization in a regulated GxP environment...  ..., hands-on experience in configuring D365, familiarity with AI applications in ERP and analytics, and exposure to label-printing... 
    Contract work

    Confidential

    Boston, MA
    3 days ago
  •  ...Head of Propulsion About the Company Startup building an orbital-class reusable launch vehicle with strong institutional backing Industry Aviation & Aerospace Type Privately Held About the Role The Company is seeking a Head of Propulsion to join... 

    Confidential

    Boston, MA
    3 days ago
  •  ...Head of Ocean Marine About the Company Established specialty MGA with capacity to launch and grow marine cargo business Industry Insurance Type Privately Held About the Role The Company is seeking a Head of Ocean Marine to build and lead its marine... 

    Confidential

    Boston, MA
    3 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Head of Core AI [Remote]. Be the first to apply!