Director - PKDM - Small Molecule Portfolio Strategy & Leadership

Amgen seeks a Director to lead pharmacokinetics/drug metabolism strategy and portfolio advancement for small molecule programs across discovery, development, and regulatory phases. The role combines scientific expertise with cross-functional project leadership to optimize candidate selection, support health authority interactions, and mentor scientific teams while shaping organizational capabilities.

Responsibilities

• Provide strategic PKDM-BA leadership for small molecule programs across discovery and development
• Drive cross-functional project teams through scientific innovation and risk assessment
• Lead PKDM-BA contributions to regulatory submissions with global health authorities
• Define scientific strategies for candidate selection, optimization, and registration
• Recruit, develop, and mentor scientific talent while fostering innovation culture

Requirements

• PhD, PharmD, or MD with 5+ years pharmaceutical sciences industry experience
• Master's degree with 8+ years pharmaceutical sciences industry experience
• Bachelor's degree with 10+ years pharmaceutical sciences industry experience
• Track record leading small molecule discovery and development programs
• Extensive experience supporting regulatory submissions (INDs, NDAs)
• Deep expertise in drug disposition, pharmacokinetics, translational strategies
• Direct people management and scientific team leadership experience